NEK7 Proteins (NEK7)

NIMA-related kinases share high amino acid sequence identity with the gene product of the Aspergillus nidulans 'never in mitosis A' gene, which controls initiation of mitosis.[supplied by OMIM, Jul 2002].. Additionally we are shipping NEK7 Antibodies (106) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NEK7 59125 Q9ES74
NEK7 140609 Q8TDX7
NEK7 360850 D3ZBE5
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Top NEK7 Proteins at antibodies-online.com

Showing 10 out of 15 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Baculovirus infected Insect Cells Human Un-conjugated 5 μg Log in to see 2 to 3 Days
$295.00
Details
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
$407.00
Details
Baculovirus infected Insect Cells Human GST tag,His tag 50 μg Log in to see 20 to 21 Days
$272.80
Details
Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$333.33
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,803.17
Details
Insect Cells Human His-GST   100 μg Log in to see 11 to 12 Days
$1,372.00
Details
Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days
$322.08
Details

NEK7 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , , , , ,
, , , ,
Rat (Rattus)

More Proteins for NEK7 Interaction Partners

Mouse (Murine) NEK7 interaction partners

  1. NEK7 serves as a cellular switch that enforces mutual exclusivity of the inflammasome response and cell division.

  2. murine macrophages deficient in Nek7 displayed a largely blunted Nlrp3 (show NLRP3 Proteins) inflammasome response.

  3. NEK7 is an essential protein that acts downstream of potassium efflux to mediate NLRP3 (show NLRP3 Proteins) inflammasome assembly and activation

  4. results confirm Nek7 as a regulator of cell division, and reveal it as an essential component for mammalian growth and survival

  5. During early embryogenesis nek7 is expressed in the site of decidual reaction. Later in embryogenesis, nek7 is highly expressed in the dorsal thalamus.

Human NEK7 interaction partners

  1. Results demonstrate that NEK7 is involved in the timely regulation of G1 progression, S-phase entry, and procentriole formation.

  2. Signaling cascade of the NIMA-related kinases (Neks) Nek6, Nek7, and Nek9 is required for the localization and function of two kinesins essential for cytokinesis, Mklp2 and Kif14 to properly coordinate cytokinesis.

  3. TRF1 (show TERF1 Proteins) phosphorylation by Nek7 favors the binding of shelterin protein TIN2 (show TINF2 Proteins) and disfavors E3 ligase Fbx4 (show FBXO4 Proteins) interaction, thus preventing TRF1 (show TERF1 Proteins) ubiquitination and proteasome degradation to maintain telomere integrity.

  4. Studies indicate that NIMA related kinase 7 (NEK7) targets at NLRP3 (show NLRP3 Proteins) protein and involves in the activation of NLRP3 (show NLRP3 Proteins) inflammasome.

  5. Study highlights for the first time the possible role of Nek7 in HCC (show FAM126A Proteins) progression. Nek7 would be a useful biomarker that early predicts HCC (show FAM126A Proteins) patients at higher risk of poor prognosis.

  6. NEK7 serves as a cellular switch that enforces mutual exclusivity of the inflammasome response and cell division.

  7. The C-terminal domain of Nek9 (show NEK9 Proteins) activates Nek7 through promoting back-to-back dimerization.

  8. Results show that NEK7 was directly regulated by WHSC1 (show WHSC1 Proteins) through H3K36me2 and its knockdown significantly reduced cell-cycle progression, indicating that NEK7 is a key player in the molecular pathway regulated by WHSC1 (show WHSC1 Proteins).

  9. RGS2 (show RGS2 Proteins) or Nek7 depletion or even overexpression of wild-type or kinase-dead Nek7, reduced gamma-tubulin (show TUBG1 Proteins) from the mitotic spindle poles.

  10. Nek7 increased Ser (show SIGLEC1 Proteins)/Thr (show TRH Proteins) phosphorylation of Anks3 primarily within ankyrin domain.Interaction with Anks3 led to cytoplasmic retention and nuclear exclusion of Nek7.

NEK7 Protein Profile

Protein Summary

NIMA-related kinases share high amino acid sequence identity with the gene product of the Aspergillus nidulans 'never in mitosis A' gene, which controls initiation of mitosis.

Gene names and symbols associated with NEK7 Proteins (NEK7)

  • NIMA (never in mitosis gene a)-related expressed kinase 7 (Nek7)
  • NIMA-related kinase 7 (nek7)
  • NIMA related kinase 7 (NEK7)
  • NIMA-related kinase 7 S homeolog (nek7.S)
  • NIMA-related kinase 7 (Nek7)
  • 2810460C19Rik protein
  • AtNek7 protein
  • AU020186 protein
  • NIMA-related kinase 7 protein
  • wu:fj68f02 protein
  • zgc:92175 protein
  • zgc:100962 protein

Protein level used designations for NEK7 Proteins (NEK7)

NIMA-related expressed kinase 7 , NIMA-related kinase 7 , never in mitosis A-related kinase 7 , nimA-related protein kinase 7 , serine/threonine-protein kinase Nek7 , NIMA (never in mitosis gene a)-related kinase 7 , NIMA-family kinase Nek7 , NIMA (never in mitosis gene a)-related expressed kinase 7

GENE ID SPECIES
59125 Mus musculus
445223 Danio rerio
424350 Gallus gallus
480008 Canis lupus familiaris
100521742 Sus scrofa
140609 Homo sapiens
414882 Xenopus laevis
781355 Bos taurus
360850 Rattus norvegicus
820397 Arabidopsis thaliana
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