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NFKB Activating Protein Proteins (NKAP)

NKAP encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. Additionally we are shipping NKAP Antibodies (23) and NKAP Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NKAP 79576 Q8N5F7
NKAP 67050 Q9D0F4
NKAP 298342 Q4V7C9
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Top NKAP Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,153.33
Details

NKAP Proteins by Origin and Source

Origin Expressed in Conjugate
Human

Mouse (Murine)

Rat (Rattus)

More Proteins for NFKB Activating Protein (NKAP) Interaction Partners

Human NFKB Activating Protein (NKAP) interaction partners

  1. NKAP is required for T cell maturation and the acquisition of functional competency

  2. NKAP is a novel nuclear regulator of TNF (show TNF Proteins)- and IL-1 (show IL1A Proteins)-induced NF-kappaB (show NFKB1 Proteins) activation

  3. NKAP functions as a transcriptional repressor, acting on Notch (show NOTCH1 Proteins) target genes, and is required for alphabeta T cell development.

Mouse (Murine) NFKB Activating Protein (NKAP) interaction partners

  1. we provide first evidence for the expression of NKAP in neurogenic cells of the adult mammalian brain

  2. Transcriptional repressor NKAP is required for invariant natural killer T cell but not conventional T cell development.

  3. NKAP is required for T cell maturation and the acquisition of functional competency

  4. Inducible deletion of NKAP in adult mice leads to lethality within 2 weeks, at which point hematopoiesis in the bone marrow has halted and hematopoietic stem cells have disappeared.

  5. NKAP is a novel nuclear regulator of TNF (show TNF Proteins)- and IL-1 (show IL1A Proteins)-induced NF-kappaB (show NFKB1 Proteins) activation

  6. NKAP functions as a transcriptional repressor, acting on Notch (show NOTCH1 Proteins) target genes, and is required for alphabeta T cell development.

NKAP Protein Profile

Protein Summary

This gene encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6.

Gene names and symbols associated with NFKB Activating Protein Proteins (NKAP)

  • NFKB activating protein (NKAP)
  • NFKB activating protein (Nkap)
  • 2610020o08rik protein
  • AA987160 protein
  • AI849147 protein
  • AL024236 protein

Protein level used designations for NFKB Activating Protein Proteins (NKAP)

NF-kappa-B-activating protein , NF-kappaB activating protein , nuclear NF-kappaB activating protein

GENE ID SPECIES
79576 Homo sapiens
67050 Mus musculus
298342 Rattus norvegicus
492098 Canis lupus familiaris
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