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Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation (By similarity). Additionally we are shipping NKIRAS2 Proteins (9) and NKIRAS2 Kits (3) and many more products for this protein.
Showing 10 out of 57 products:
Human Polyclonal NKIRAS2 Primary Antibody for ELISA, WB - ABIN1002701
Chen, Wu, Ghosh: KappaB-Ras binds to the unique insert within the ankyrin repeat domain of IkappaBbeta and regulates cytoplasmic retention of IkappaBbeta x NF-kappaB complexes. in The Journal of biological chemistry 2003
Show all 2 Pubmed References
Human Monoclonal NKIRAS2 Primary Antibody for IHC (p), ELISA - ABIN565391
Murphy, Guyre, Pioli: Estradiol suppresses NF-kappa B activation through coordinated regulation of let-7a and miR-125b in primary human macrophages. in Journal of immunology (Baltimore, Md. : 1950) 2010
GBM cells overexpressing TNFAIP3 (show TNFAIP3 Antibodies) and NKIRAS2 were refractory to miR (show MLXIP Antibodies)-125b-induced apoptosis resistance as well as TMZ resistance, indicating that both genes are relevant targets of miR (show MLXIP Antibodies)-125b.
KappaB-Ras2 is a nuclear-cytoplasmic small GTPase (show RACGAP1 Antibodies) that inhibits NF-kappaB (show NFKB1 Antibodies) activation through the suppression of transcriptional activation of p65/RelA (show NFkBP65 Antibodies).
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation (By similarity).
NFKB inhibitor interacting Ras-like 2
, I-kappa-B-interacting Ras-like protein 2
, NF-kappa-B inhibitor-interacting Ras-like protein 2
, kappa B-Ras protein 2
, NFKB inhibitor interacting Ras-like protein 2