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NKRF encodes a transcriptional repressor that interacts with specific negative regulatory elements to mediate transcriptional repression of certain nuclear factor kappa B responsive genes. Additionally we are shipping NFKB Repressing Factor Kits (7) and NFKB Repressing Factor Proteins (6) and many more products for this protein.
Showing 10 out of 42 products:
Human Polyclonal NKRF Primary Antibody for IHC (p), WB - ABIN390606
Ho, Lee, Chan, Kuo, Ito, Adcock, Chen, Sheu, Lin, Kuo: Neutrophil elastase represses IL-8/CXCL8 synthesis in human airway smooth muscle cells through induction of NF-kappa B repressing factor. in Journal of immunology (Baltimore, Md. : 1950) 2009
Show all 2 references for ABIN390606
Human Polyclonal NKRF Primary Antibody for EIA, WB - ABIN453224
Glanz, Albrecht, Heinemann, Fleckenstein, Isakov, Biesinger: NF-kappaB activation by the viral oncoprotein StpC enhances IFN-gamma production in T cells. in Immunology and cell biology 2008
Show all 2 references for ABIN453224
Cow (Bovine) Polyclonal NKRF Primary Antibody for WB - ABIN2774943
Reboll, Oumard, Gazdag, Renger, Ritter, Schwarzer, Hauser, Wood, Yamada, Resch, Nourbakhsh: NRF IRES activity is mediated by RNA binding protein JKTBP1 and a 14-nt RNA element. in RNA (New York, N.Y.) 2007
vitamin E supplementation affords protection by decreasing MMP-1 (show MMP1 Antibodies) and increasing PPARg (show PPARG Antibodies), GSTa (show GSTa2 Antibodies), and ABCA1 (show ABCA1 Antibodies) levels in aortae of rabbits fed a cholesterol-rich diet
MIR29 targets and reduces expression of CLDN1 (show CLDN1 Antibodies) and NKRF to increase intestinal permeability in inflammatory bowel disease.
The data of this study show that JKTBP1 and the 14-nt element act independently to mediate NRF internal ribosome entry segment activity.
NF-kappaB-repressing factor (NKRF) phosphorylation modulates promoter-proximal transcription elongation of NF-kappaB (show NFKB1 Antibodies)/NKRF-regulated genes via direct interactions with elongation complex in response to specific stimuli
The up-regulated NKRF serves as an endogenous repressor for IP-10 (show CXCL10 Antibodies) and IL-8 (show IL8 Antibodies) synthesis to hinder host from robust response to MTb (show NCAPG2 Antibodies) infection.
NRF may serve as an endogenous repressor to prevent robust increase in IP-10/CXCL10 (show CXCL10 Antibodies) and IL-8/CXCL8 (show IL8 Antibodies) when TB bacterial load is high.
The expression of NKRF is decreased in PBMCs of patients with stable COPD (show ARCN1 Antibodies). The downregulation of NKRF was found to be closely related to enhanced IL-8 (show IL8 Antibodies) production from these peripheral blood cells through de-repression of the IL-8 (show IL8 Antibodies) promoter.
The results indicate that JKTBP1 regulates the level of NRF protein expression by binding to both NRF 5' and 3' UTRs.
role of NF-kappa B-repressing factor (NRF) in basal repression of the hiNOS gene
cDNA is 3247 bp long, contains three exons and maps to human chromosome Xq24. NRF is widely expressed in human tissues.
Full-length NRF is highly enriched in nucleoli and only a small fraction of NRF is found in the nucleoplasm and cytoplasm
NRF interrupts the regulatory coupling of LTR binding factors and transcription elongation events; this inhibitory mechanism might contribute to transcriptional quiescence of integrated HIV-1 provirus
GRK5 overexpression causes nuclear accumulation of IkappaB alpha, leading to the inhibition of NFkappaB transcriptional activity.
This gene encodes a transcriptional repressor that interacts with specific negative regulatory elements to mediate transcriptional repression of certain nuclear factor kappa B responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm. Alternate splicing results in multiple transcript variants.
NFKB repressing factor
, transcription factor NRF
, NF-kappaB repressing factor
, nkrf (NF-kappaB repressing factor)
, NF-kappa-B-repressing factor-like
, NF-kappa-B-repressing factor
, NFkB-repressing factor