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NFU1 Iron-Sulfur Cluster Scaffold Homolog (S. Cerevisiae) (NFU1) ELISA Kits

NFU1 encodes a protein that is localized to mitochondria and plays a critical role in iron-sulfur cluster biogenesis. Additionally we are shipping NFU1 Iron-Sulfur Cluster Scaffold Homolog (S. Cerevisiae) Antibodies (4) and NFU1 Iron-Sulfur Cluster Scaffold Homolog (S. Cerevisiae) Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human NFU1 NFU1 27247 Q9UMS0
Anti-Mouse NFU1 NFU1 56748 Q9QZ23
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More ELISA Kits for NFU1 Iron-Sulfur Cluster Scaffold Homolog (S. Cerevisiae) Interaction Partners

Human NFU1 Iron-Sulfur Cluster Scaffold Homolog (S. Cerevisiae) (NFU1) interaction partners

  1. A new NFU1 mutation is reported in a patient presenting with a milder phenotype characterized by a later onset, a slowly progressive spastic paraparesis with relapsing-remitting episodes, mild cognitive impairment and a long survival.

  2. This study provides new insights into the molecular bases of NFU1 disease.

  3. A fatal mitochondrial disease is associated with defective NFU1 function in the maturation of a subset of mitochondrial Fe-S proteins

  4. Mutations in iron-sulfur cluster scaffold genes NFU1 and BOLA3 (show BOLA3 ELISA Kits) cause a fatal deficiency of multiple respiratory chain and 2-oxoacid dehydrogenase enzymes [case report]

  5. Analyses of genomic DNA, transcripts, and translation products indicate that alternative splicing of a common pre-mRNA results in synthesis of two Nfu isoforms with distinct subcellular localizations.

  6. Laforin (show EPM2A ELISA Kits) interacts with HIRIP5.

  7. NFU binds to NifS and reduces the persulfide bond on activated NifS (following formation of the persulfide bond by abstraction of S from the Cys amino acid), yielding inorganic sulfide on a time frame that is compatible with Fe-S cluster assembly.

  8. NFU is a functionally competent reducing agent for cysteinyl persulfide bond cleavage, releasing inorganic sulfide for incorporation into the iron-sulfur-bound [2Fe-2S] cluster, a reactivity that may be facilitated by flexibility of the C-terminal domain.

NFU1 Iron-Sulfur Cluster Scaffold Homolog (S. Cerevisiae) (NFU1) Antigen Profile

Antigen Summary

This gene encodes a protein that is localized to mitochondria and plays a critical role in iron-sulfur cluster biogenesis. The encoded protein assembles and transfers 4Fe-4S clusters to target apoproteins including succinate dehydrogenase and lipoic acid synthase. Mutations in this gene are a cause of multiple mitochondrial dysfunctions syndrome-1, and pseudogenes of this gene are located on the short arms of chromosomes 1 and 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with NFU1

  • NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae) (NFU1) antibody
  • NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae) (Nfu1) antibody
  • 0610006G17Rik antibody
  • CGI-33 antibody
  • HIRIP antibody
  • Hirip5 antibody
  • MMDS1 antibody
  • Nfu antibody
  • NifU antibody
  • NIFUC antibody

Protein level used designations for NFU1

HIRA-interacting protein 5 , NFU1 iron-sulfur cluster scaffold homolog, mitochondrial , NifU-like C-terminal domain containing , iron-sulfur cluster scaffold protein , histone cell cycle regulation defective interacting protein 5 , mHIRIP5

GENE ID SPECIES
27247 Homo sapiens
56748 Mus musculus
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