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anti-NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2) Antibodies

NAB2 encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. Additionally we are shipping NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) Proteins (5) and NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NAB2 17937 Q61127
NAB2 314910  
NAB2 4665 Q15742
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Top anti-NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) Antibodies at antibodies-online.com

Showing 10 out of 92 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of NAB2 antibody (Center) (ABIN391957) in A375 c... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from HT-29/RAW264.7 cells, using NAB... Immunohistochemistry analysis of paraffin-embedded human brain tissue,... 100 μg Log in to see 2 to 3 Days
$275.00
Details
Mouse Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-NAB2 Antibody Titration: 1.25ug/mlELISA Titer: 1:156... WB Suggested Anti-NAB2  Antibody Titration: 1.25 µg/mL ELISA Titer: 1:... 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated ICC, IF, IP, IHC (p), WB ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed HeL... WB Image Sample (30 ug of whole cell lysate) A: A431 7.5% SDS PAGE ant... 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB 50 μL Log in to see 8 to 10 Days
$451.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of NAB2 staining in human breast cancer f... Western blot analysis of NAB2 expression in HepG2 (A), HeLa (B), Raw26... 200 μL Log in to see 9 Days
$487.50
Details

NAB2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine) , , , ,

Rat (Rattus) , , , ,

Human , , , ,
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Top referenced anti-NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) Antibodies

  1. Human Polyclonal NAB2 Primary Antibody for WB - ABIN391957 : Srinivasan, Mager, Ward, Mayer, Svaren: NAB2 represses transcription by interacting with the CHD4 subunit of the nucleosome remodeling and deacetylase (NuRD) complex. in The Journal of biological chemistry 2006 (PubMed)
    Show all 3 references for ABIN391957

  2. Human Polyclonal NAB2 Primary Antibody for IHC, ELISA - ABIN1533922 : Kirsch, Korradi, Johnson: Mader: a novel nuclear protein over expressed in human melanomas. in Oncogene 1996 (PubMed)
    Show all 2 references for ABIN1533922

  3. Cow (Bovine) Polyclonal NAB2 Primary Antibody for WB - ABIN2780731 : Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006 (PubMed)

More Antibodies against NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) Interaction Partners

Mouse (Murine) NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2) interaction partners

  1. Data suggest that histone deacetylase (show HDAC1 Antibodies) inhibitors inhibit the induction of NGF1A-binding protein (show NAB1 Antibodies) Nab2 by brain derived neurotrophic factor (BDNF (show BDNF Antibodies)), and thereby the relative induction of dopamine and cyclic AMP-regulated phosphoprotein (show ARPP21 Antibodies), 32 kDa (DARPP-32 (show PPP1R1B Antibodies)).

  2. Nab2 is a novel endogenous negative regulator of Egr-1 (show EGR1 Antibodies)-dependent TGF-beta (show TGFB1 Antibodies) signaling responsible for setting the intensity of fibrotic responses

  3. Nab1 and Nab2 proteins are necessary for Schwann cells to exit the cell cycle, downregulate suppressed cAMP-inducible protein (SCIP) expression and upregulate expression of critical myelination genes.

  4. repression of the endogenous Rad (show RRAD Antibodies) gene by NAB2 involves interaction with the CHD4 (chromodomain helicase DNA-binding protein 4 (show CHD4 Antibodies)) subunit of the NuRD (nucleosome remodeling and deacetylase) chromatin remodeling complex

  5. NAB2 enhances IL-2 (show IL2 Antibodies) transcription by acting as a coactivator for Egr-1 (show EGR1 Antibodies).NAB2 is recruited to the Egr-1 (show EGR1 Antibodies) binding site of the IL-2 (show IL2 Antibodies) promoter.

  6. We report here, that FGF23 (show FGF23 Antibodies) induces not only Egr-1 (show EGR1 Antibodies) but also two isoforms of NAB2, which are specific co-repressors of Egr-1 (show EGR1 Antibodies).

Human NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2) interaction partners

  1. We delineate the common and rare NAB2-STAT6 (show STAT6 Antibodies) fusion variants in solitary fibrous tumors

  2. This study confirms that meningeal Meningeal solitary fibrous tumor and hemangiopericytoma represent a histopathologic continuum linked by STAT6 (show STAT6 Antibodies) nuclear expression and NAB2-STAT6 (show STAT6 Antibodies) fusion similar to their soft tissue counterparts.

  3. This study validated the existence of the NAB2-STAT6 (show STAT6 Antibodies) fusion gene in solitary fibrous tumors and examined its relation with pathological features.

  4. also identified NAB2-STAT6 (show STAT6 Antibodies) fusions in two hemangiopericytomas diagnosed in the past with a common variant of NAB2ex6-STAT6ex16/17

  5. There was no association between solitary fibrous tumors with either NAB2 exon 4-STAT6 (show STAT6 Antibodies) exon 2 or 3 fusion and tumors with other fusions regarding the frequency of mutations in the examined genes (P = .201).

  6. reverse transcriptase PCR analysis identified a nerve growth factor inducible-A binding protein 2-STAT6 (show STAT6 Antibodies) gene fusion. Our case supports the utility of STAT6 (show STAT6 Antibodies) immunohistochemistry as an adjunct in the diagnosis of soft-tissue SFT (show UBE2D1 Antibodies) with loss of CD34 (show CD34 Antibodies) positivity

  7. 44 SFTs were studied to identify pathogenetically important genetic rearrangements. RT-PCR analysis identified a NAB2/STAT6 (show STAT6 Antibodies) fusion in 37/41 cases.

  8. Meningeal hemangiopericytoma and solitary fibrous tumors carry the NAB2-STAT6 (show STAT6 Antibodies) fusion

  9. NAB2 and EGR-1 (show EGR1 Antibodies) exert opposite roles in regulating TRAIL expression in human Natural Killer cells.

  10. A gene fusion of the transcriptional repressor NAB2 with the transcriptional activator STAT6 (show STAT6 Antibodies) is the defining driver mutation of solitary fibrous tumor.

NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2) Antigen Profile

Protein Summary

This gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Gene names and symbols associated with NAB2

  • NGFI-A binding protein 2 (EGR1 binding protein 2) (nab2) antibody
  • Ngfi-A binding protein 2 (Nab2) antibody
  • NGFI-A binding protein 2 (EGR1 binding protein 2) (NAB2) antibody
  • AI451907 antibody
  • MADER antibody

Protein level used designations for NAB2

NGFI-A binding protein 2 (EGR1 binding protein 2) , EGR-1-binding protein 2 , NGFI-A binding protein 2 (EGR-1 binding protein 2) , NGFI-A-binding protein 2 , EGR1 binding protein 2 , melanoma-associated delayed early response protein

GENE ID SPECIES
100145178 Xenopus (Silurana) tropicalis
17937 Mus musculus
314910 Rattus norvegicus
4665 Homo sapiens
504755 Bos taurus
481122 Canis lupus familiaris
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