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NIMA-Related Kinase 8 (NEK8) ELISA Kits

NEK8 encodes a member of the serine/threionine protein kinase family related to NIMA (never in mitosis, gene A) of Aspergillus nidulans. Additionally we are shipping NEK8 Antibodies (82) and NEK8 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse NEK8 NEK8 140859 Q91ZR4
Anti-Human NEK8 NEK8 284086 Q86SG6
Anti-Rat NEK8 NEK8 287473  
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More ELISA Kits for NEK8 Interaction Partners

Mouse (Murine) NIMA-Related Kinase 8 (NEK8) interaction partners

  1. NEK8-depleted inner medullary collecting duct cells exhibited a defective response to fluid shear.

  2. Nek8 acts downstream of Inv (show INVS ELISA Kits) function

  3. Inv (show INVS ELISA Kits) acts as a molecular anchor for Nphp3 (show NPHP3 ELISA Kits) and Nek8 in the proximal segment of primary cilia.

  4. cross-species analysis between zebrafish and mouse demonstrates taht NEK8 has a role in development of pronephric cysts

  5. Nek8 and Pkd1 (show PKD1 ELISA Kits) genes function in a common pathway to regulate cystogenesis. Moreover, compound Pkd1 (show PKD1 ELISA Kits) and Nek8 heterozygous adult mice develop a more aggressive cystic disease than animals with a mutation in either gene alone.

  6. Defects in ciliary localization of Nek8 is associated with polycystic kidney diseases

Zebrafish NIMA-Related Kinase 8 (NEK8) interaction partners

  1. requirement for Nek8 in left-right patterning is conserved

  2. Nek8 acts downstream of Inv (show INVS ELISA Kits) function

  3. cross-species analysis between zebrafish and mouse demonstrates taht NEK8 has a role in development of pronephric cysts

Human NIMA-Related Kinase 8 (NEK8) interaction partners

  1. our study demonstrates that NEK8 (show NEK9 ELISA Kits) human mutations cause major organ developmental defects due to altered ciliogenesis and cell differentiation/proliferation through deregulation of the Hippo pathway

  2. NEK8 (show NEK9 ELISA Kits) may be a new target gene of HIFs; pVHL (show VHL ELISA Kits) can down-regulate NEK8 (show NEK9 ELISA Kits) via HIFs to maintain the primary cilia structure in human renal cancer cells

  3. NEK8 (show NEK9 ELISA Kits) is essential for organ development and that the complete loss of NEK8 (show NEK9 ELISA Kits) perturbs multiple signalling pathways resulting in a severe early embryonic phenotype.

  4. Mutation in NEK8 (show NEK9 ELISA Kits) is associated with renal ciliopathies

  5. ANKS6 as a new NPHP family member that assembles a distinct module of nephronophthisis-associated proteins, encompassing NEK8 (show NEK9 ELISA Kits), INVS (show INVS ELISA Kits) and NPHP3 (show NPHP3 ELISA Kits).

  6. NPHP9 promotes signalling through the transcriptional co-activator TAZ (show TAZ ELISA Kits).

  7. study finds that induction of ciliogenesis upon cell cycle exit is accompanied by both activation and proteasomal degradation of Nek8 (show NEK9 ELISA Kits), and that activation is dependent upon phosphorylation within the catalytic domain

  8. Data demonstrate for the first time that Nek8 (show NEK9 ELISA Kits) is a novel tumor associated gene, and shares considerable sequence homology with the Nek family of protein kinases and may be involved in G(2)/M progression.

NEK8 Antigen Profile

Antigen Summary

This gene encodes a member of the serine/threionine protein kinase family related to NIMA (never in mitosis, gene A) of Aspergillus nidulans. The encoded protein may play a role in cell cycle progression from G2 to M phase. Mutations in the related mouse gene are associated with a disease phenotype that closely parallels the juvenile autosomal recessive form of polycystic kidney disease in humans.

Gene names and symbols associated with NIMA-Related Kinase 8 (NEK8) ELISA Kits

  • NIMA (never in mitosis gene a)- related kinase 8 (NEK8) antibody
  • NIMA (never in mitosis gene a)-related expressed kinase 8 (Nek8) antibody
  • NIMA (never in mitosis gene a)-related kinase 8 (nek8) antibody
  • NIMA-related kinase 8 (NEK8) antibody
  • NIMA-related kinase 8 (Nek8) antibody
  • 4632401F23Rik antibody
  • b2b1449Clo antibody
  • JCK antibody
  • NEK12A antibody
  • NPHP9 antibody

Protein level used designations for NIMA-Related Kinase 8 (NEK8) ELISA Kits

serine/threonine-protein kinase Nek8 , NIMA-related expressed kinase 8 , juvenile cystic kidney , never in mitosis A-related kinase 8 , nimA-related protein kinase 8 , NIMA-related kinase 8 , NIMA (never in mitosis gene a)- related kinase 8 , NIMA-family kinase NEK8 , NIMA-related kinase 12a , nephrocystin 9 , nima-related protein kinase 12a , serine/thrionine-protein kinase NEK8 , NIMA (never in mitosis gene a)-related expressed kinase 8

GENE ID SPECIES
417576 Gallus gallus
491171 Canis lupus familiaris
532332 Bos taurus
140859 Mus musculus
171094 Danio rerio
284086 Homo sapiens
287473 Rattus norvegicus
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