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anti-NK2 Homeobox 1 (NKX2-1) Antibodies

NKX2-1 encodes a protein initially identified as a thyroid-specific transcription factor. Additionally we are shipping NK2 Homeobox 1 Kits (21) and NK2 Homeobox 1 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NKX2-1 7080 P43699
NKX2-1 21869 P50220
NKX2-1 25628  
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Top anti-NK2 Homeobox 1 Antibodies at antibodies-online.com

Showing 10 out of 202 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p) Flow cytometric analysis of rabbit anti-TTF-1 (SP141) antibody in HeLa (green) compare to negative control of rabbit IgG (blue). 1 mL Log in to see 2 to 3 Days
$648.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, treated with EGF 200ng/ml 30', using TEBP (Ab-113) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using TEBP (Ab-113) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB Immunohistochemistry of NKX2-1 in human lung tissue with NKX2-1 antibody at 2.5 ug/mL. Western blot analysis of NKX2-1 in rat lung tissue lysate with NKX2-1 antibody at (A) 1 and (B) 2 ug/mL. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated FACS, WB NKX2-1 Antibody (N-term) (ABIN654691) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$346.50
Details
Human Rabbit Un-conjugated IHC (p) Flow cytometric analysis of rabbit anti-TTF-1 (SP141) antibody in HeLa (green) compare to negative control of rabbit IgG (blue). 7 mL Log in to see 2 to 3 Days
$367.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from NIH-3T3 cells treated with EGF 200ng/ml 30', using TEBP (Phospho-Ser113) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using TEBP (Phospho-Ser113) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated EIA, FACS, WB Flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram) using TTF1 / NKX2A  Antibody (N-term), followed by FITC-conjugated secondary antibodies. Western blot analysis in Hela cell line lysates (35ug/lane) using TTF1 / NKX2A  Antibody (N-term). This demonstrates this antibody detected the NKX2-1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated IHC (p) 1 mL Log in to see 6 to 8 Days
$665.50
Details
Human Rabbit Un-conjugated WB NKX2-1 Antibody (Center)  western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the NKX2-1 antibody detected the NKX2-1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details

NKX2-1 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-NK2 Homeobox 1 Antibodies

  1. Human Monoclonal NKX2-1 Primary Antibody for FACS, IHC (p) - ABIN1688762 : Vyberg, Nielsen: Proficiency testing in immunohistochemistry-experiences from Nordic Immunohistochemical Quality Control (NordiQC). in Virchows Archiv : an international journal of pathology 2016 (PubMed)
    Show all 5 references for ABIN1688762

  2. Human Polyclonal NKX2-1 Primary Antibody for EIA, IF - ABIN1450126 : Guazzi, Price, De Felice, Damante, Mattei, Di Lauro: Thyroid nuclear factor 1 (TTF-1) contains a homeodomain and displays a novel DNA binding specificity. in The EMBO journal 1990 (PubMed)
    Show all 4 references for ABIN1450126

  3. Human Polyclonal NKX2-1 Primary Antibody for IHC, ELISA - ABIN1532418 : Freeman, Yamamoto: Disassembly of transcriptional regulatory complexes by molecular chaperones. in Science (New York, N.Y.) 2002 (PubMed)

More Antibodies against NK2 Homeobox 1 Interaction Partners

Human NK2 Homeobox 1 (NKX2-1) interaction partners

  1. In adenocarcinomas from extrahepatic biliary tract, there was no correlation between TTF-1 expression and the clinicopathological characteristics.

  2. Suggest TTF-1 is a reliable marker in non-small cell lung carcinoma and can be used in differential diagnosis.

  3. EGFR (show EGFR Antibodies) knockdown led to upregulation of NKX2-1, suggesting a negative feedback loop. combined knockdown of NKX2-1 and EGFR (show EGFR Antibodies) in NCI-H1819 lung cancer cells reduced cell proliferation more than knockdown of either alone.

  4. TTF-1 had no prognostic value concerning OS, but may serve as a predictor for response to first line chemotherapy in small cell lung cancer.

  5. Authors suggest that NKX2-1 as a tumour suppressor or a tumour promoter in lung adenocarcinoma progression is dependent on p53 (show TP53 Antibodies) status.

  6. TTF-1 is considered to be an excellent marker of pituicytes, specialized glia of the neurohypophysis.

  7. Aberrant expression of mir (show MLXIP Antibodies)-365/TTF-1 may be involved in the tumor development in patients with non-small cell lung carcinoma.

  8. Different staining patterns can be seen with CK5 (show KRT5 Antibodies)/6 and p63 (show RPE65 Antibodies); however, if they are used together with TTF-1 they can be used in subtyping lung neoplasms.

  9. No TTF1 or EAP1 germline mutations were associated with central pubertal disorders. TTF1 and EAP1 may affect puberty by changing expression in response to other members of puberty-associated gene networks

  10. Loss of TTF-1 is associated with low response to chemotherapy in non-small-cell lung cancer.

Mouse (Murine) NK2 Homeobox 1 (NKX2-1) interaction partners

  1. Identify regulatory link between Nkx2-1, miR (show MLXIP Antibodies)-200c, and the transcription factors Nfib (show NFIB Antibodies) and Myb (show MYB Antibodies), adding new players to the regulatory mechanisms driven by Nkx2-1 in lung epithelial cells that may have implications in lung development and tumorigenesis.

  2. A population of neural stem cells in the ventral region of the adult ventricular-subventricular zone expresses the transcription factor Nkx2.1 and is derived from Nkx2.1-expressing (Nkx2.1+) embryonic precursors.

  3. We conclude that a dedicated subset of VMHVL neurons marked by ERalpha (show ESR1 Antibodies), NKX2-1, and Tac1 (show TAC1 Antibodies) regulates estrogen-dependent fluctuations in physical activity and constitutes one of several neuroendocrine modules that drive sex-specific responses.

  4. Prototypic GPe neurons derive from the medial ganglionic eminence of the embryonic subpallium and express the transcription factor Nkx2-1. These neurons fire at high rates during alert rest, and encode movements through heterogeneous firing rate changes.

  5. Molecular characterization of disseminated tumor cells indicates that downregulation of the transcription factor Nkx2-1 precedes lung adenocarcinoma dissemination.

  6. The Nkx2-1-mediated pathway in the DMH (show DST Antibodies) and LH stimulates skeletal muscle function via the sympathetic nervous system and maintains youthful physiology, contributing to the delay in aging and life span extension.

  7. MicroRNA-33a mediates the regulation of high mobility group AT-hook 2 gene (HMGA2) by thyroid transcription factor 1 (TTF-1/NKX2-1).

  8. A review of recent findings with special attention given to the role of NKX2-1 in lung development and carcinogenesis.

  9. we report the generation of transgenic mouse lines that overexpress wild-type p23 (show CDK5R1 Antibodies) or uncleavable p23 (show CDK5R1 Antibodies)

  10. Apc (show APC Antibodies) and TGF-beta (show TGFB1 Antibodies) signaling have roles in regulating the key transcriptional factor, Nkx2.1, for lung epithelial progenitor cell fate determination

NK2 Homeobox 1 (NKX2-1) Antigen Profile

Protein Summary

This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TFF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription.

Gene names and symbols associated with anti-NK2 Homeobox 1 (NKX2-1) Antibodies

  • thyroid transcription factor 1 (titf1-A) antibody
  • NK2 homeobox 1 (NKX2-1) antibody
  • thyroid transcription factor 1 (LOC100227803) antibody
  • NK2 homeobox 1 (Nkx2-1) antibody
  • prostaglandin E synthase 3 (cytosolic) (Ptges3) antibody
  • thyroid transcription factor 1-like (LOC100154384) antibody
  • 5730442A20Rik antibody
  • AV026640 antibody
  • BCH antibody
  • BHC antibody
  • cPGES antibody
  • LOC100227803 antibody
  • NK-2 antibody
  • NKX2-1 antibody
  • Nkx2.1 antibody
  • NKX2A antibody
  • p23 antibody
  • Ptges antibody
  • sid3177 antibody
  • T/EBP antibody
  • Tebp antibody
  • Titf1 antibody
  • titf1-A antibody
  • Ttf-1 antibody
  • TTF1 antibody
  • Xnkx-2.1 antibody

Protein level used designations for anti-NK2 Homeobox 1 (NKX2-1) Antibodies

thyroid transcription factor 1 , NK2 homeobox 1 , NK-2 homolog A , homeobox protein NK-2 homolog A , homeobox protein Nkx-2.1 , thyroid nuclear factor 1 , thyroid-specific enhancer-binding protein , tinman , TTF-1 , thyroid transcription factor 1 TTF-1 NK-2 , thyroid transcription factor-1 , homeodomain protein NKx2.1 , cytosolic prostaglandin E2 synthase , hsp90 co-chaperone , p23 cochaperone , progesterone receptor complex p23 , prostaglandin E synthase 3 , sid 3177 , telomerase binding protein, p23 , telomerase-binding protein p23

GENE ID SPECIES
373626 Xenopus laevis
452867 Pan troglodytes
100227803 Taeniopygia guttata
7080 Homo sapiens
21869 Mus musculus
25628 Rattus norvegicus
403940 Canis lupus familiaris
395322 Gallus gallus
56351 Mus musculus
100154384 Sus scrofa
Selected quality suppliers for anti-NK2 Homeobox 1 (NKX2-1) Antibodies
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