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anti-NK2 Homeobox 5 (NKX2-5) Antibodies

NKX2-5 encodes a homeobox-containing transcription factor. Additionally we are shipping NK2 Homeobox 5 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NKX2-5 1482 P52952
NKX2-5 18091 P42582
NKX2-5 114109 O35767
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Top anti-NK2 Homeobox 5 Antibodies at antibodies-online.com

Showing 10 out of 116 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Nkx2-5 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Goat Un-conjugated EIA, WB Anti-CSX1 (0.3µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated ELISA, WB Figure 1: Western blot analysis using NKX2.5 mouse mAb against full-length NKX2.5 (aa1-324) -hIgGFc transfected HEK293 cell lysate (1) . 100 μL Log in to see 3 to 4 Days
$393.80
Details
Human Rabbit Un-conjugated WB Anti- NKX2 Picoband antibody, Western blotting All lanes: Anti NKX2  at 0.5ug/ml Lane 1: Mouse Spleen Tissue Lysate at 50ug Lane 2: Mouse Cardiac Muscle Tissue Lysate at 50ug Lane 3: HELA Whole Cell Lysate at 40ug Predicted bind size: 35KD Observed bind size: 35KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated ELISA, WB NKX2-5 monoclonal antibody (M01), clone 1E4-G5. Western Blot analysis of NKX2-5 expression in human thyroid(diffuse hyperplasia). NKX2-5 monoclonal antibody (M01), clone 1E4-G5 Western Blot analysis of NKX2-5 expression in HeLa . 100 μg Log in to see 9 Days
$430.00
Details
Human Goat Un-conjugated IHC (p), ELISA, WB Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB NKX2-5 Antibody (Center)  western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the NKX2-5 antibody detected the NKX2-5 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ICC, IF, WB ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed mouse ESC D3, using Nkx2.5, antibody at 1:200 dilution. ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using NKX2-5, antibody at 1:200 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Mouse Un-conjugated WB Western Blot analysis of NKX2-5 expression in transfected 293T cell line by NKX2-5 monoclonal antibody (M01), clone 1E4-G5. Lane 1: NKX2-5 transfected lysate(34.9 KDa). Lane 2: Non-transfected lysate. NKX2-5 monoclonal antibody (M01), clone 1E4-G5. Western Blot analysis of NKX2-5 expression in human thyroid(diffuse hyperplasia). 0.1 mg Log in to see 8 to 11 Days
$450.00
Details

NKX2-5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-NK2 Homeobox 5 Antibodies

  1. Human Monoclonal NKX2-5 Primary Antibody for ELISA, WB - ABIN560515 : Yadava, Frenzel-McCardell, Yu, Srinivasan, Tucker, Puymirat, Thornton, Prall, Harvey, Mahadevan: RNA toxicity in myotonic muscular dystrophy induces NKX2-5 expression. in Nature genetics 2007 (PubMed)
    Show all 2 references for ABIN560515

  2. Human Monoclonal NKX2-5 Primary Antibody for ELISA, WB - ABIN969487 : Ikeda, Hiroi, Hosoda, Utsunomiya, Matsuo, Ito, Inoue, Sumiyoshi, Takano, Nagai, Komuro: Novel point mutation in the cardiac transcription factor CSX/NKX2.5 associated with congenital heart disease. in Circulation journal : official journal of the Japanese Circulation Society 2002 (PubMed)
    Show all 2 references for ABIN969487

  3. Cow (Bovine) Polyclonal NKX2-5 Primary Antibody for EIA, WB - ABIN615913 : Briggs, Takeda, Cuadra, Wakimoto, Marks, Walker, Seki, Oh, Lu, Sumners, Raizada, Horikoshi, Weinberg, Yasui, Ikeda, Chien, Kasahara: Perinatal loss of Nkx2-5 results in rapid conduction and contraction defects. in Circulation research 2008 (PubMed)

  4. Cow (Bovine) Polyclonal NKX2-5 Primary Antibody for WB - ABIN2779388 : Nagel, Meyer, Quentmeier, Kaufmann, Drexler, MacLeod: MEF2C is activated by multiple mechanisms in a subset of T-acute lymphoblastic leukemia cell lines. in Leukemia 2008 (PubMed)

More Antibodies against NK2 Homeobox 5 Interaction Partners

Human NK2 Homeobox 5 (NKX2-5) interaction partners

  1. the frequency of NKX2.5 gene mutations among the patient with Atrial septal defect: in 80% of the affected individuals two polymorphic sites are located at position 487 and 495.

  2. The crystal structure and binding domains were identified in cardiac NKX2.5.

  3. We describe in this study the mutational and expression analysis of the NKX2.5 gene in nonsyndromic CHD (show CHDH Antibodies) patients

  4. NKX2.5 mutations were not found. The c.63A>G polymorphism might be associated with thyroid hypoplasia.

  5. Our findings demonstrate that somatic NKX2-5 mutations do not represent an important aetiologic pathway in Chinese children with congenital heart disease.

  6. Combined expression of NKX2-5, HAND1 (show HAND1 Antibodies), and NOTCH1 (show NOTCH1 Antibodies) coordinately contribute to cardiac malformations in Hhypoplastic left heart syndrome.

  7. The novel DSV (1500G>C) of NKX2-5 gene (show GPD1 Antibodies) may contribute to a small number of VSD, and rs2277923 SNP may contribute to the risk of sporadic ASD (show ARSD Antibodies) in Chinese Yunnan population.

  8. Nkx2-5 (and Isl1 (show ISL1 Antibodies)) regulate the specification of cardiac progenitor cells and acquisition of cardiomyocyte subtype identity.

  9. Germline mutations in the NKX2-5, GATA4 (show GATA4 Antibodies), and CRELD1 (show CRELD1 Antibodies) genes do not appear to be associated with CHD (show CHDH Antibodies) in Mexican DS patients.

  10. NKX2-5 is thus responsible for dominant familial ASD (show ARSD Antibodies) even in consanguineous populations, and a wide genetic and phenotypic diversity is characteristic of NKX2-5 mutations in the Lebanese population.

Mouse (Murine) NK2 Homeobox 5 (NKX2-5) interaction partners

  1. Study reports extensive and complex interdependent genomic occupancy of TBX5 (show TBX5 Antibodies), NKX2-5, and the zinc finger TF GATA4 (show GATA4 Antibodies) coordinately controlling cardiac gene expression, differentiation, and morphogenesis.

  2. Sequential binding of MEIS1 (show MEIS1 Antibodies) and NKX2-5 on the Popdc2 (show POPDC2 Antibodies) gene demonstrate a mechanism for spatiotemporal regulation of enhancers during cardiogenesis.

  3. The model proposed will help to elucidate the molecular basis for disease causing mutations in GATA4 and NKX2-5 and may be relevant to other members of the GATA and NK classes of transcription factors.

  4. MSCs thus form a 'mechanical memory' of rigidity by progressively suppressing NKX2.5, thereby elevating SMA (show SMN1 Antibodies) in a scar-like state.

  5. the Shox2 (show SHOX2 Antibodies)-Nkx2-5 antagonistic mechanism primes the pacemaker cell fate in the pulmonary vein myocardium and sinoatrial node

  6. Findings implicate a novel, temporal-specific role of Mzf1 (show ZSCAN1 Antibodies) in embryonic heart development and show that Mzf1 (show ZSCAN1 Antibodies) bounds directly to the Nkx2.5 during murine embryonic stem cell differentiation.

  7. A heterozygous Nkx2-5 missense mutation in the homeodomain demonstrates a high penetrance of diverse cardiac anomalies, similar to or more profound than those observed in human patients.

  8. our findings reveal a novel mechanism for regulation of SCFFbox25-dependent Nkx2-5 and Tbx5 (show TBX5 Antibodies) ubiquitination in cardiac development and provide a new insight into the regulatory mechanism of Nkx2-5 and Tbx5 (show TBX5 Antibodies) transcriptional activity.

  9. Results show that NKX2-5 mRNA levels correlate with muscle histopathology in mice and humans and find that NKX2-5 levels modify disease phenotypes in mice with RNA toxicity.

  10. role for Nkx2-5 and Gata3 (show GATA3 Antibodies) in the ontogeny of the smooth muscle gastric ligaments; gastric ligaments coexpress Gata3 (show GATA3 Antibodies), Nkx2-5 and Sox9 (show SOX9 Antibodies); germline loss of Gata3 (show GATA3 Antibodies) or conditional deletion of Nkx2-5 abrogates Sox9 (show SOX9 Antibodies) expression and impairs gastric ligament smooth muscle development

NK2 Homeobox 5 (NKX2-5) Antigen Profile

Protein Summary

This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with anti-NK2 Homeobox 5 (NKX2-5) Antibodies

  • NK2 transcription factor related, locus 5 (Drosophila) (NKX2-5) antibody
  • Nkx2.5 protein (nkx2.5) antibody
  • NK2 transcription factor related, locus 5 (nkx2-5) antibody
  • NK2 homeobox 5 (NKX2-5) antibody
  • NK2 homeobox 5 (Nkx2-5) antibody
  • Nkx-2.5 homeobox protein (NKX-2.5) antibody
  • CHNG5 antibody
  • CNKX-2.5 antibody
  • Csx antibody
  • CSX1 antibody
  • HLHS2 antibody
  • NKX-2.5 antibody
  • Nkx2-5 antibody
  • NKX2.5 antibody
  • NKX2E antibody
  • NKX4-1 antibody
  • tinman antibody
  • VSD3 antibody
  • XNkx-2.5 antibody
  • XNkx2-5 antibody

Protein level used designations for anti-NK2 Homeobox 5 (NKX2-5) Antibodies

NK2 transcription factor related, locus 5 (Drosophila) , NK2 transcription factor locus 5-like , Nkx2.5 protein , NK2 transcription factor related, locus 5 , cardiac-specific homeobox 1 , homeobox protein CSX , homeobox protein NK-2 homolog E , homeobox protein Nkx-2.5 , tinman paralog , transcription factor NKX2.5 , Drosophila NK2 transcription factor related, locus 5 , cardiac-specific homeobox , rNKx-2.5

GENE ID SPECIES
462273 Pan troglodytes
703795 Macaca mulatta
100026700 Monodelphis domestica
100125478 Oryzias latipes
100144646 Xenopus (Silurana) tropicalis
1482 Homo sapiens
489113 Canis lupus familiaris
538870 Bos taurus
18091 Mus musculus
114109 Rattus norvegicus
396073 Gallus gallus
100009490 Oryctolagus cuniculus
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