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NK2 Homeobox 6 Proteins (NKX2-6)

NKX2-6 encodes a homeobox-containing protein that belongs to the NK-2 homeobox family. Additionally we are shipping NK2 Homeobox 6 Antibodies (42) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NKX2-6 137814 A6NCS4
NKX2-6 18092 P43688
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Top NK2 Homeobox 6 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

NKX2-6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

More Proteins for NK2 Homeobox 6 (NKX2-6) Interaction Partners

Xenopus laevis NK2 Homeobox 6 (NKX2-6) interaction partners

  1. Results suggest that XNkx2-10, like XNkx2-3 and XNkx2-5, is necessary for normal Xenopus heart development.

Human NK2 Homeobox 6 (NKX2-6) interaction partners

  1. This study firstly links NKX2.6 loss-of-function mutation with increased susceptibility to isolated VSD.

  2. Data associated genetically defective NK2 homeobox 6 (NKX2-6) with enhanced susceptibility to atrial fibrillation (AF).

  3. Heterozygous mutations in Nkx2.6, p.V176M and p.K177X, were identified in 2 unrelated patients, one with tetralogy of Fallot and one with double outlet of right ventricle and ventricular septal defect. Increased vulnerability to TOF or DORV is discussed.

  4. NKX2-6 plays a role in human cardiogenesis.

  5. weakly activates transcription of a Cx40 (show GJA5 Proteins) promoter, may have role in heart development

  6. NKX2.5 (show NKX2-5 Proteins)/NKX2.6 mutations are not a common cause of isolated type 1 truncus arteriosus in a small cohort of multiethnic cases.

NK2 Homeobox 6 (NKX2-6) Protein Profile

Protein Summary

This gene encodes a homeobox-containing protein that belongs to the NK-2 homeobox family. This protein is a vertebrate homolog of Drosophila homeobox-containing protein called 'tinman', which has been shown to be essential for development of the heart-like dorsal vessel. In conjunction with related gene, NKX2-5, this gene may play a role in both pharyngeal and cardiac embryonic development. Mutations in this gene are associated with persistent truncus arteriosus.

Gene names and symbols associated with NK2 Homeobox 6 Proteins (NKX2-6)

  • NK2 transcription factor related, locus 6 (nkx2-6)
  • NK2 homeobox 6 (NKX2-6)
  • NK2 transcription factor related, locus 6 (Drosophila) (NKX2-6)
  • NK2 homeobox 6 (Nkx2-6)
  • AV044928 protein
  • CSX2 protein
  • Nkx-2.6 protein
  • nkx2-10-A protein
  • Nkx2.6 protein
  • NKX2.8 protein
  • NKX2F protein
  • NKX4-2 protein
  • tinman protein
  • Tix protein
  • Xnkx2-10 protein

Protein level used designations for NK2 Homeobox 6 Proteins (NKX2-6)

NK2 transcription factor related, locus 6 , homeodomain protein XNkx2-10 , homeobox protein Nkx-2.6 , homeobox protein Nkx-2.8 , NK2 transcription factor related, locus 6 (Drosophila) , homeobox protein NK2 homolog F , homeobox protein NKX2.6 , tinman paralog , Drosophila NK2 transcription factor related, locus 6 , homeobox protein NK-2 homolog F

GENE ID SPECIES
373736 Xenopus laevis
396037 Gallus gallus
464060 Pan troglodytes
486113 Canis lupus familiaris
100038094 Xenopus (Silurana) tropicalis
137814 Homo sapiens
18092 Mus musculus
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