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NK3 Homeobox 2 Proteins (NKX3-2)

NKX3-2 encodes a member of the NK family of homeobox-containing proteins. Additionally we are shipping NK3 Homeobox 2 Antibodies (51) and NK3 Homeobox 2 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NKX3-2 579 P78367
NKX3-2 12020 P97503
Rat NKX3-2 NKX3-2 682329  
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Top NK3 Homeobox 2 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,887.50
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

NKX3-2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for NK3 Homeobox 2 (NKX3-2) Interaction Partners

Zebrafish NK3 Homeobox 2 (NKX3-2) interaction partners

  1. Bapx1-endothelin 1 (show EDN1 Proteins) effector, patterns jaw joint

Human NK3 Homeobox 2 (NKX3-2) interaction partners

  1. PI3K (show PIK3CA Proteins)-mediated suppression of Nkx3.2 in chondrocytes plays a role in the control of cartilage hypertrophy during skeletal development in vertebrates.

  2. Our findings indicate that BAPX-1/NKX-3.2 is a molecular switch that is involved in controlling the hypertrophic phenotype of the postdevelopmental (OA) articular chondrocyte.

  3. Ihh (show IHH Proteins)-induced Nkx3.2 degradation requires Wnt5a (show WNT5A Proteins), which is capable of triggering Nkx3.2 degradation

  4. Data show that IkappaB kinase (show CHUK Proteins) beta (IKKbeta (show IKBKB Proteins)) can be activated in the nucleus by Nkx3.2 in the absence of exogenous IKK (show CHUK Proteins)-activating signals, allowing constitutive nuclear degradation of IkappaB-alpha (show NFKBIA Proteins).

  5. NKX3-2 plays an important role in endochondral ossification of both the axial and appendicular skeleton in humans

  6. Data show that Meox1 (show MEOX1 Proteins) activates the Bapx1 promoter in a dose-dependent manner and that this activity is enhanced in the presence of Pax1 (show PAX1 Proteins) and/or Pax9 (show PAX9 Proteins).

Mouse (Murine) NK3 Homeobox 2 (NKX3-2) interaction partners

  1. Nkx3.2 promotes primary chondrogenesis by two mechanisms: Direct and Sox9 (show SOX9 Proteins)-independent upregulation of Col2a1 (show COL2A1 Proteins) transcription and upregulation of Sox9 (show SOX9 Proteins) mRNA expression under positive feedback system.

  2. the balance of Pax3 (show PAX3 Proteins), Nkx3.2 and Sox9 (show SOX9 Proteins) may act as a molecular switch during the chondrogenic differentiation of muscle progenitor cells, which may be important for fracture healing.

  3. These results demonstrated that Nkx3.2-dependent suppression of Runx2 (show RUNX2 Proteins) was a crucial factor in hypoxia-dependent maintenance of chondrocyte identity.

  4. Data show that IkappaB kinase (show CHUK Proteins) beta (IKKbeta (show IKBKB Proteins)) can be activated in the nucleus by Nkx3.2 in the absence of exogenous IKK (show CHUK Proteins)-activating signals, allowing constitutive nuclear degradation of IkappaB-alpha (show NFKBIA Proteins).

  5. Targeted disruption of the Nkx3.2 (Bapx1) gene in mice results in limited defects of chondrocranial bones and the axial skeleton, particularly pronounced in cervical vertebrae.

  6. Pax1 (show PAX1 Proteins) and Pax9 (show PAX9 Proteins) can transactivate regulatory sequences in the Bapx1 promoter to induce chondrogenic differentiation in the sclerotome.

  7. Nkx3.2 has a critical role in the induction of somitic chondrogenesis

  8. Data show that Meox1 (show MEOX1 Proteins) activates the Bapx1 promoter in a dose-dependent manner and that this activity is enhanced in the presence of Pax1 (show PAX1 Proteins) and/or Pax9 (show PAX9 Proteins).

  9. in the Bapx1 mutant embryo, Fgf10 (show FGF10 Proteins) expression is downregulated and the dorsal pancreas remains at the midline

  10. Nkx3.2 represses expression of the chondrocyte maturation factor Runx2 (show RUNX2 Proteins), and Runx2 (show RUNX2 Proteins) mis (show AMH Proteins)-expression can rescue the Nkx3.2-induced blockade of chondrocyte maturation.

NK3 Homeobox 2 (NKX3-2) Protein Profile

Protein Summary

This gene encodes a member of the NK family of homeobox-containing proteins. The encoded protein may play a role in skeletal development.

Gene names and symbols associated with NK3 Homeobox 2 Proteins (NKX3-2)

  • NK3 homeobox 2 (LOC100220828)
  • NK3 homeobox 2 (LOC100344387)
  • NK3 homeobox 2 (nkx3.2)
  • NK3 homeobox 2 (nkx3-2)
  • NK3 homeobox 2 (NKX3-2)
  • NK3 homeobox 2 (Nkx3-2)
  • Bapx1 protein
  • bapx1-A protein
  • Nkx-3.2 protein
  • NKX3.2 protein
  • NKX3B protein
  • SMMD protein
  • Xbap protein

Protein level used designations for NK3 Homeobox 2 Proteins (NKX3-2)

NK3 homeobox 2 , bagpipe homeobox homolog 1 , homeobox protein Nkx-3.2 , bagpipe homeobox protein homolog 1 , NK class homeoprotein Nkx-3.2 , homeobox protein NK-3 homolog B , bagpipe homeobox gene 1 homolog , homeodomain protein Nkx-3.2

GENE ID SPECIES
100220828 Taeniopygia guttata
100344387 Oryctolagus cuniculus
337865 Danio rerio
378569 Xenopus laevis
373932 Gallus gallus
579 Homo sapiens
488822 Canis lupus familiaris
12020 Mus musculus
616907 Bos taurus
682329 Rattus norvegicus
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