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anti-NLR Family, CARD Domain Containing 5 (NLRC5) Antibodies

NLRC5 encodes a member of the caspase recruitment domain-containing NLR family.

list all antibodies Gene Name GeneID UniProt
NLRC5 84166 Q86WI3
NLRC5 434341 C3VPR6
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Top anti-NLRC5 Antibodies at antibodies-online.com

Showing 10 out of 14 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IF, WB Western blot analysis of NOD4 in EL4 cell lysate with NOD4 antibody at 1 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB 50 μg Log in to see 11 to 13 Days
$541.80
Details
Human Rabbit Un-conjugated ICC, ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$330.00
Details
Human Rabbit Un-conjugated WB   50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ICC, IF, ELISA, WB   100 μg Log in to see 15 to 19 Days
$455.07
Details
Human Rabbit Un-conjugated ELISA, WB 0.1 mg Log in to see 6 to 11 Days
$535.71
Details
Human Rabbit Un-conjugated ELISA, WB   0.1 mg Log in to see 2 to 6 Days
$359.70
Details

NLRC5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human


Mouse (Murine)


Top referenced anti-NLRC5 Antibodies

  1. Human Polyclonal NLRC5 Primary Antibody for EIA, IF - ABIN783699 : Benko, Magalhaes, Philpott, Girardin: NLRC5 limits the activation of inflammatory pathways. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 2 references for ABIN783699

More Antibodies against NLRC5 Interaction Partners

Human NLR Family, CARD Domain Containing 5 (NLRC5) interaction partners

  1. NLRC5 regulates TGFB1 (show TGFB1 Antibodies)-induced proliferation and activation of hepatic stellate cells during hepatic fibrosis.

  2. In a transformed cell line, NLRC5 plays a significant role in IL-6 (show IL6 Antibodies) and IL-1Beta (show IL1B Antibodies) secretion.

  3. NLRC5 function is shaped by reversible ubiquitination, which modulates the NF-kappaB (show NFKB1 Antibodies) activation switch

  4. RSV infection of lung epithelial cells induces expression of RIG-I, NLRC5, and subsequent upregulation of HLA-A, HLA-B and HLA-C.

  5. a novel role for NLRC5 in RIG-I-mediated antiviral host responses against influenza virus infection, distinguished from the role of NLRC5 in MHC class I gene regulation.

  6. This study presents a detailed functional study of the domains of NLRC5 revealing that the N-terminal domain of human NLRC5 has intrinsic transcriptional activity.

  7. Unusual structural features revealed by the solution NMR structure of the NLRC5 caspase (show CASP3 Antibodies) recruitment domain.

  8. A model for full-length human NLRC5 was prepared and, besides the closed conformation of monomeric NLRC5, a heptameric platform was also modeled for the opened conformational NLRC5 monomers.

  9. rhinovirus ion channel protein (show TRPC3 Antibodies) 2B triggers NLRP3 (show NLRP3 Antibodies) and NLRC5 inflammasome activation and IL-1beta (show IL1B Antibodies) secretion in bronchial cells

  10. Expression of NLRC5 positively correlates with histocompatibility class I expression in human tissues.

Mouse (Murine) NLR Family, CARD Domain Containing 5 (NLRC5) interaction partners

  1. NLRC5 regulates TGFB1 (show TGFB1 Antibodies)-induced proliferation and activation of hepatic stellate cells during hepatic fibrosis.

  2. NLRC5 is differentially expressed in hepatic tissues and hepatic stellate cells during hepatic fibrosis and its reversal

  3. NLRC5 expression in T cells is required to protect them from NK-cell-mediated elimination upon inflammation.

  4. NLRC5 and CIITA (show CIITA Antibodies) thus emerge as paradigms for a novel class of transcriptional regulators dedicated for transactivating extremely few, phylogenetically related genes.

  5. Unusual structural features revealed by the solution NMR structure of the NLRC5 caspase (show CASP3 Antibodies) recruitment domain.

  6. Data conclude that Nlrc5 is important in the regulation of MHC-I expression by reducing H3K27me3 on MHC-I promoter and joins CIITA as an NLR subfamily that controls MHC gene transcription.

  7. NLRC5 is required for both constitutive and inducible histocompatibility class I gene expression and host defense.

  8. NLRC5 ablation reduces MHC class I expression, and enhances IKK (show CHUK Antibodies) and IRF3 (show IRF3 Antibodies) phosphorylation in response to TLR stimulation or viral infection.

  9. NLRC5-deficient mice showed a profound defect in the expression of MHC class I genes and a concomitant failure to activate L. monocytogenes-specific CD8 (show CD8A Antibodies)(+) T cell responses, including activation, proliferation and cytotoxicity.

  10. NLRC5 overexpression promotes interleukin (IL)-1beta (show IL1B Antibodies) production via caspase-1 (show CASP1 Antibodies) and is dispensable for cytokine induction in virus and bacterial infections under physiologic conditions.

NLRC5 Antigen Profile

Protein Summary

This gene encodes a member of the caspase recruitment domain-containing NLR family. This gene plays a role in cytokine response and antiviral immunity through its inhibition of NF-kappa-B activation and negative regulation of type I interferon signaling pathways.

Gene names and symbols associated with NLRC5

  • NLR family, CARD domain containing 5 (NLRC5) antibody
  • NLR family, CARD domain containing 5 (nlrc5) antibody
  • NLR family, CARD domain containing 5 (Nlrc5) antibody
  • AI451557 antibody
  • AK220210 antibody
  • CLR16.1 antibody
  • NOD4 antibody
  • NOD27 antibody

Protein level used designations for NLRC5

NLR family, CARD domain containing 5 , protein NLRC5 , NOD-like receptor C5 , caterpiller protein 16.1 , nucleotide-binding oligomerization domain protein 4 , nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 5 , nucleotide-binding oligomerization domains 27

GENE ID SPECIES
487268 Canis lupus familiaris
703437 Macaca mulatta
782441 Bos taurus
100021163 Monodelphis domestica
100052017 Equus caballus
100135667 Sus scrofa
100303710 Ictalurus punctatus
100476937 Ailuropoda melanoleuca
84166 Homo sapiens
434341 Mus musculus
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