anti-NLR Family, CARD Domain Containing 5 (NLRC5) Antibodies

NLRC5 encodes a member of the caspase recruitment domain-containing NLR family.

list all antibodies Gene Name GeneID UniProt
NLRC5 84166 Q86WI3
NLRC5 434341 C3VPR6
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Top anti-NLRC5 Antibodies at antibodies-online.com

Showing 10 out of 16 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IF, WB   0.1 mg Log in to see 10 to 12 Days
$375.38
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
$451.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IF, ELISA, WB   100 μg Log in to see 15 to 19 Days
$466.62
Details
Human Rabbit Un-conjugated ICC, ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$340.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated ICC, IF Immunocytochemistry/Immunofluorescence: NLRC5 Antibody  - Staining of human cell line SiHa shows localization to centrosome. 100 μL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated WB   50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, ICC, WB   100 μg Log in to see 11 to 12 Days
$324.80
Details
Human Rabbit Un-conjugated ELISA, WB   0.1 mg Log in to see 2 to 6 Days
$327.00
Details

NLRC5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human ,


Mouse (Murine)


More Antibodies against NLRC5 Interaction Partners

Pig (Porcine) NLR Family, CARD Domain Containing 5 (NLRC5) interaction partners

  1. The NLRC5 transcript in pigs is relatively conservative among mammals and may play a vital role in immune reaction, which provides a basis for further studies on the NLRC5 function in the pig immune system and the role in comparative immunity.

Human NLR Family, CARD Domain Containing 5 (NLRC5) interaction partners

  1. NLRC5 interacts with miR (show MLXIP Antibodies)-34a.NLRC5 role in HPV16 persistence.

  2. These results demonstrate that NLRC5 promotes hepatocellular carcinoma progression via the AKT (show AKT1 Antibodies)/VEGF-A (show VEGFA Antibodies) signaling pathway

  3. NLRC5 not only positively correlates with the increase of beta-catenin (show CTNNB1 Antibodies) but also coordinates the activation of downstream Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling pathway, regulating cell proliferation, migration and invasion in hepatocellular carcinoma.

  4. silencing NLRC5 reduced extracellular matrix expression in keloid fibroblasts through inhibiting the TGF-beta1 (show TGFB1 Antibodies)/Smad (show SMAD1 Antibodies) signaling pathway.

  5. CITA/NLRC5 and CIITA are transcriptional regulators that orchestrate the concerted expression of critical components in the MHC class I and class II pathways, respectively. [review]

  6. NLRC5 expression was significantly associated with the activation of CD8 (show CD8A Antibodies)(+) cytotoxic T cells and patient survival in multiple cancer types. Thus, NLRC5 constitutes a novel prognostic biomarker and potential therapeutic target of cancers.

  7. NLRC5 regulates TGFB1 (show TGFB1 Antibodies)-induced proliferation and activation of hepatic stellate cells during hepatic fibrosis.

  8. In a transformed cell line, NLRC5 plays a significant role in IL-6 (show IL6 Antibodies) and IL-1Beta (show IL1B Antibodies) secretion.

  9. NLRC5 function is shaped by reversible ubiquitination, which modulates the NF-kappaB (show NFKB1 Antibodies) activation switch

  10. RSV infection of lung epithelial cells induces expression of RIG-I, NLRC5, and subsequent upregulation of HLA-A, HLA-B and HLA-C.

Mouse (Murine) NLR Family, CARD Domain Containing 5 (NLRC5) interaction partners

  1. NLRC5 knockout in mice exhibited greater hepatic injury after hepatic ischemia/reperfusion (I/R) injury.

  2. The observed increases in viral titers in NLRC5-deficient mice correlated with impaired effector CD8 (show CD8A Antibodies)(+) T cell responses. Although NLRC5-deficient mice were defective at clearing the virus, they did not show an increase in morbidity or mortality following influenza virus infection because of other compensatory immune mechanisms.

  3. NLRC5 regulates TGFB1 (show TGFB1 Antibodies)-induced proliferation and activation of hepatic stellate cells during hepatic fibrosis.

  4. NLRC5 is differentially expressed in hepatic tissues and hepatic stellate cells during hepatic fibrosis and its reversal

  5. NLRC5 expression in T cells is required to protect them from NK-cell-mediated elimination upon inflammation.

  6. NLRC5 and CIITA (show CIITA Antibodies) thus emerge as paradigms for a novel class of transcriptional regulators dedicated for transactivating extremely few, phylogenetically related genes.

  7. Unusual structural features revealed by the solution NMR structure of the NLRC5 caspase (show CASP3 Antibodies) recruitment domain.

  8. Data conclude that Nlrc5 is important in the regulation of MHC-I expression by reducing H3K27me3 on MHC-I promoter and joins CIITA as an NLR subfamily that controls MHC gene transcription.

  9. NLRC5 is required for both constitutive and inducible histocompatibility class I gene expression and host defense.

  10. NLRC5 ablation reduces MHC class I expression, and enhances IKK (show CHUK Antibodies) and IRF3 (show IRF3 Antibodies) phosphorylation in response to TLR stimulation or viral infection.

NLRC5 Antigen Profile

Protein Summary

This gene encodes a member of the caspase recruitment domain-containing NLR family. This gene plays a role in cytokine response and antiviral immunity through its inhibition of NF-kappa-B activation and negative regulation of type I interferon signaling pathways.

Gene names and symbols associated with NLRC5

  • NLR family, CARD domain containing 5 (NLRC5) antibody
  • NLR family, CARD domain containing 5 (nlrc5) antibody
  • NLR family, CARD domain containing 5 (Nlrc5) antibody
  • AI451557 antibody
  • AK220210 antibody
  • CLR16.1 antibody
  • NOD4 antibody
  • NOD27 antibody

Protein level used designations for NLRC5

NLR family, CARD domain containing 5 , protein NLRC5 , NOD-like receptor C5 , caterpiller protein 16.1 , nucleotide-binding oligomerization domain protein 4 , nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 5 , nucleotide-binding oligomerization domains 27

GENE ID SPECIES
487268 Canis lupus familiaris
703437 Macaca mulatta
782441 Bos taurus
100021163 Monodelphis domestica
100052017 Equus caballus
100135667 Sus scrofa
100303710 Ictalurus punctatus
100476937 Ailuropoda melanoleuca
84166 Homo sapiens
434341 Mus musculus
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