NLR Family, Pyrin Domain Containing 5 (NLRP5) ELISA Kits

The protein encoded by NLRP5 belongs to the NALP protein family. Additionally we are shipping NLR Family, Pyrin Domain Containing 5 Antibodies (21) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human NLRP5 NLRP5 126206 P59047
Anti-Mouse NLRP5 NLRP5 23968 Q9R1M5
Anti-Rat NLRP5 NLRP5 308325  
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More ELISA Kits for NLR Family, Pyrin Domain Containing 5 Interaction Partners

Human NLR Family, Pyrin Domain Containing 5 (NLRP5) interaction partners

  1. PSMG4 and NLRP5 appear of particular interest as they were found to be associated with more than one clinical phenotype and are implicated in biological processes considered relevant to the pathophysiology of MS. Also, PSMG4 p.W99R and NLRP5 p.R761L were found to correlate with an earlier age of MS clinical onset. Our data suggests PSMG4 and NLPR5 as potential targets for the development of modifying therapies for MS.

  2. expression of MATER and NOX4 (show NOX4 ELISA Kits) proteins are closely related to the follicular development and ovulation with particular regard for ovarian aging

  3. NLRP5 mutation is associated with multilocus imprinting disorders and reproductive wastage.

  4. characterization of the MATER gene and its protein; this provides a basis for investigating their clinical implications in autoimmune premature ovarian failure and infertility in women

  5. NALP5 appears to be a tissue-specific autoantigen involved in hypoparathyroidism in patients with APS-1. Autoantibodies against NALP5 appear to be highly specific and may be diagnostic for this prominent component of APS-1

  6. MATER protein interacts with tPKCepsilon in cumulus cells under physiological conditions.

Mouse (Murine) NLR Family, Pyrin Domain Containing 5 (NLRP5) interaction partners

  1. The expression of Mater protein is decreased in mature oocytes from old versus young mice.

  2. MATER is part of the subcortical maternal complex (SCMC). SCMC is required for formation of the cytoplasmic F-actin meshwork that controls the central position of the spindle and ensures symmetric division.

  3. MATER is required for endoplasmic reticulum distribution and Ca2 (show CA2 ELISA Kits)+ homeostasis in oocytes, likely due to defects in lattice-mediated ER positioning and/or redistribution.

  4. It was concluded that lack of Nlrp5 in oocytes triggers premature activation of the mitochondrial pool, causing mitochondrial damage that cannot be rescued by inactivation of Bax (show BAX ELISA Kits).

  5. Transgenic expression of MATER induces antigen-specific tolerance with a significant reduction in ovarian autoimmunity.

  6. MATER co-localizes with PADI6 (show PADI6 ELISA Kits) at the oocyte cytoplasmic lattices.

  7. Mater gene transcription and protein translation are active during oogenesis, but appear inactive during early embryogenesis

  8. MATER and three similar genes are localized to mouse chromosome 7

  9. The plasticity of the FILIA-MATER complex localization may reflect the regulative nature of preimplantation mouse development.

  10. Results describe a subcortical maternal complex, containing Mater, Floped, TLE6, and Filia, that is essential for preimplantation mouse embryogenesis.

Cow (Bovine) NLR Family, Pyrin Domain Containing 5 (NLRP5) interaction partners

  1. Assignment to a QTL region for reproductive traits and preferential expression of NALP9 (show NLRP9 ELISA Kits), NALP8, and NALP5 in oocyte, germinal lineage, and gonad cells may suggest their functional relevance to reproduction and possible contribution to phenotypic variation

  2. In situ hybridization confirmed oocyte-restricted expression of MATER within the ovary, as early as preantral follicle stages.

  3. expression patterns are consistent with bovine MATER protein being an oocyte specific maternal effect factor (show ZAR1 ELISA Kits) as in mouse

NLR Family, Pyrin Domain Containing 5 (NLRP5) Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). Expression of this gene is restricted to the oocyte. A mouse gene that encodes a maternal oocyte protein, similar to this encoded protein, is required for normal early embryogenesis.

Gene names and symbols associated with NLRP5

  • NLR family, pyrin domain containing 5 (NLRP5) antibody
  • NLR family, pyrin domain containing 5 (Nlrp5) antibody
  • CLR19.8 antibody
  • Mater antibody
  • Nalp5 antibody
  • Op1 antibody
  • PAN11 antibody
  • PYPAF8 antibody

Protein level used designations for NLRP5

NACHT, LRR and PYD domains-containing protein 5 , NACHT, leucine rich repeat and PYD containing 5 , mater protein homolog , maternal antigen that embryos require , nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 5 , maternal effect , ooplasm , ooplasm-specific protein 1

126206 Homo sapiens
23968 Mus musculus
308325 Rattus norvegicus
493717 Bos taurus
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