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NOBOX Oogenesis Homeobox Proteins (NOBOX)

This homeobox gene encodes a transcription factor that is thought to play a role in oogenesis. Additionally we are shipping NOBOX Antibodies (28) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NOBOX 135935 O60393
NOBOX 18291 Q8VIH1
Rat NOBOX NOBOX 502759  
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Top NOBOX Proteins at

Showing 2 out of 2 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 39 to 44 Days

NOBOX Proteins by Origin and Source

Origin Expressed in Conjugate

Mouse (Murine)

More Proteins for NOBOX Oogenesis Homeobox (NOBOX) Interaction Partners

Human NOBOX Oogenesis Homeobox (NOBOX) interaction partners

  1. High prevalence of the association between the NOBOX rare variants and Primary ovarian insufficiency.

  2. both NOBOX and FOXL2 (show FOXL2 Proteins) are expressed in human follicle granulosa cells and their interaction plays an inhibitory role in the transcriptional response of these promoters.

  3. The very high 6.2% prevalence of these new mutations in POI patients suggest considering NOBOX as the first autosomal candidate gene involved in this syndrome.

  4. Mutations of the homeobox (show Lbx1 Proteins) region of the NOBOX gene are uncommon in Japanese patients with premature ovarian failure.

  5. NOBOX expression within adult human tissues is limited to the testis, pancreas and oocyte specific in ovary.

  6. These findings demonstrate that NOBOX mutations can cause premature ovarian failure.

  7. Mutations in the homeobox (show Lbx1 Proteins) domain of NOBOX are not common explanations for POF (show POF1B Proteins) in Chinese women.

Mouse (Murine) NOBOX Oogenesis Homeobox (NOBOX) interaction partners

  1. The NOBOX protein is expressed throughout oocyte growth in the nucleus of ovarian Non Surrounded Nucleolus and in MII(Non Surrounded Nucleolus) oocytes; beginning with Surrounded Nucleolus oocytes of 61-70 microm, it becomes almost undetectable.

  2. These results indicate that premature ovarian failure syndrome in Nobox deficient mice results from the faulty signaling between somatic and germ line components during embryonic development.

  3. identified one Nobox DNA-binding element within the Pad6 promoter. findings indicate that Nobox is a critical regulator that orchestrates oocyte-specific genes such as Pad6 during folliculogenesis.

  4. Nobox is critical for specifying an oocyte-restricted gene expression pattern essential for postnatal follicle development

  5. NOBOX directly regulates the transcription of Pou5f1 (show POU5F1 Proteins) and Gdf9 (show GDF9 Proteins) in oocytes during early folliculogenesis

  6. findings indicate that Nobox is likely an activator of oocyte-specific gene expression

  7. RT-PCR data shows an increase in oogenesis specific gene transcripts (Nobox, Oct4 (show POU5F1 Proteins), Bmp15 (show BMP15 Proteins), Gdf9 (show GDF9 Proteins), Oogenesin1 and Oogenesin2) between the primordial until the preantral stages, with the exception of the Oogenesin1 transcripts under gonadotropin-induction.

Pig (Porcine) NOBOX Oogenesis Homeobox (NOBOX) interaction partners

  1. The expression levels of this gene in heart, kidney and oocytes are higher than that in other tissues, which suggested that the NOBOX protein might play an important role in those tissues.

Cow (Bovine) NOBOX Oogenesis Homeobox (NOBOX) interaction partners

  1. Results demonstrate that miR (show MYLIP Proteins)-196a is a bona fide negative regulator of NOBOX during bovine early embryogenesis.

  2. This study demonstrates that NOBOX is an essential maternal-derived transcription factor during bovine early embryogenesis, which functions in regulation of embryonic genome activation, pluripotency gene expression, and blastocyst cell allocation.

NOBOX Protein Profile

Protein Summary

This homeobox gene encodes a transcription factor that is thought to play a role in oogenesis. In mice, it is essential for folliculogenesis and regulation of oocyte-specific genes. Defects in this gene result in premature ovarian failure type 5.

Gene names and symbols associated with NOBOX

  • NOBOX oogenesis homeobox (NOBOX)
  • NOBOX oogenesis homeobox (Nobox)
  • OG-2 protein
  • OG2 protein
  • Og2x protein
  • POF5 protein
  • RGD1563929 protein
  • TCAG_12042 protein

Protein level used designations for NOBOX

NOBOX oogenesis homeobox , homeobox protein NOBOX-like , homeobox protein NOBOX , newborn ovary homeobox-encoding , OG2 homeobox , homeodomain-containing protein OG-2 , newborn ovary homeobox protein , oocyte-specific homeobox protein

472575 Pan troglodytes
706128 Macaca mulatta
100058413 Equus caballus
100438747 Pongo abelii
100606571 Nomascus leucogenys
135935 Homo sapiens
18291 Mus musculus
482717 Canis lupus familiaris
100499552 Sus scrofa
528414 Bos taurus
502759 Rattus norvegicus
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