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N-ethylmaleimide-sensitive factor (NSF) and valosin-containing protein (p97) are two ATPases known to be involved in transport vesicle/target membrane fusion and fusions between membrane compartments. Additionally we are shipping NSFL1C Antibodies (18) and NSFL1C Proteins (6) and many more products for this protein.
p47 (show ING1 ELISA Kits) promotes, whereas SASK1 delays the degradation of a single ERAD substrate, alpha-TCR. Additionally, we found that SAKS1 (show UBXN1 ELISA Kits) selectively inhibits the degradation of ERAD substrates without affecting cytosolic proteasomal substrates.
The present results for the first time demonstrate that BDNF (show BDNF ELISA Kits) induces NADPH oxidase (show NOX1 ELISA Kits) -derived reactive oxygen species generation through activation of p47 phox in a TrkB (show NTRK2 ELISA Kits) receptor-dependent manner
human p37 (show CCNH ELISA Kits)/p47 (show ING1 ELISA Kits) and their C. elegans orthologue UBXN-2 regulate centrosome function in prophase by limiting the recruitment of Aurora A (show AURKA ELISA Kits)
The binding of p47 (show ING1 ELISA Kits) to polyubiquitinated NEMO (show IKBKG ELISA Kits) triggers the lysosomal degradation of NEMO (show IKBKG ELISA Kits), thereby inhibiting IKK (show CHUK ELISA Kits) activation.
Data suggest that NADPH oxidase (show NOX1 ELISA Kits)-derived cytosolic superoxide is increased in islets upon oleate exposure and leads to beta cell dysfunction; whole-body NADPH oxidase (show NOX1 ELISA Kits) inhibition (via p47 (show MFGE8 ELISA Kits) knockout) decreases superoxide and restores islet function.
that p47 (show MFGE8 ELISA Kits) ubiquitin regulatory X domain domains may act as general p97/valosin containing protein (show vcp ELISA Kits)/CDC48 (show vcp ELISA Kits) binding modules and that adaptor binding for N-ethylmaleimide sensitive factor (show NSF ELISA Kits) and p97 (show EIF4G2 ELISA Kits) might involve different binding sites
genetic ablation of components of NADPH oxidase (show NOX1 ELISA Kits) enhances susceptibility to the proinflammatory effects of CS leading to airspace enlargement and alveolar damage.
N-ethylmaleimide-sensitive factor (NSF) and valosin-containing protein (p97) are two ATPases known to be involved in transport vesicle/target membrane fusion and fusions between membrane compartments. A trimer of the protein encoded by this gene binds a hexamer of cytosolic p97 and is required for p97-mediated regrowth of Golgi cisternae from mitotic Golgi fragments. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8.
, NSFL1 cofactor p47
, NSFL1 (p97) cofactor (p47)
, p97 cofactor p47
, NSFL1 cofactor p47-like
, SHP1 homolog
, UBX domain-containing protein 2C
, XY body-associated protein XY40