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N-ethylmaleimide-sensitive factor (NSF) and valosin-containing protein (p97) are two ATPases known to be involved in transport vesicle/target membrane fusion and fusions between membrane compartments. Additionally we are shipping NSFL1C Antibodies (12) and many more products for this protein.
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The present results for the first time demonstrate that BDNF (show BDNF Proteins) induces NADPH oxidase (show NOX1 Proteins) -derived reactive oxygen species generation through activation of p47 phox in a TrkB (show NTRK2 Proteins) receptor-dependent manner
human p37 (show CCNH Proteins)/p47 (show ING1 Proteins) and their C. elegans orthologue UBXN-2 regulate centrosome function in prophase by limiting the recruitment of Aurora A (show AURKA Proteins)
The binding of p47 (show ING1 Proteins) to polyubiquitinated NEMO (show IKBKG Proteins) triggers the lysosomal degradation of NEMO (show IKBKG Proteins), thereby inhibiting IKK (show CHUK Proteins) activation.
Data suggest that NADPH oxidase (show NOX1 Proteins)-derived cytosolic superoxide is increased in islets upon oleate exposure and leads to beta cell dysfunction; whole-body NADPH oxidase (show NOX1 Proteins) inhibition (via p47 (show MFGE8 Proteins) knockout) decreases superoxide and restores islet function.
that p47 (show MFGE8 Proteins) ubiquitin regulatory X domain domains may act as general p97/valosin containing protein (show vcp Proteins)/CDC48 (show vcp Proteins) binding modules and that adaptor binding for N-ethylmaleimide sensitive factor (show NSF Proteins) and p97 (show EIF4G2 Proteins) might involve different binding sites
genetic ablation of components of NADPH oxidase (show NOX1 Proteins) enhances susceptibility to the proinflammatory effects of CS leading to airspace enlargement and alveolar damage.
N-ethylmaleimide-sensitive factor (NSF) and valosin-containing protein (p97) are two ATPases known to be involved in transport vesicle/target membrane fusion and fusions between membrane compartments. A trimer of the protein encoded by this gene binds a hexamer of cytosolic p97 and is required for p97-mediated regrowth of Golgi cisternae from mitotic Golgi fragments. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8.
, NSFL1 cofactor p47
, NSFL1 (p97) cofactor (p47)
, p97 cofactor p47
, NSFL1 cofactor p47-like
, SHP1 homolog
, UBX domain-containing protein 2C
, XY body-associated protein XY40