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Stress-activated kinase involved in tolerance to glucose starvation. Additionally we are shipping NUAK Family, SNF1-Like Kinase, 2 Antibodies (72) and NUAK Family, SNF1-Like Kinase, 2 Proteins (6) and many more products for this protein.
miR143 inhibited the proliferation, migration and invasion of the glioblastoma cells by degrading NUAK2 in glioblastoma.
Sucrose non-fermenting AMPK (show PRKAA1 ELISA Kits) related kinase/Pentraxin 3 (show PTX3 ELISA Kits) combined role in immunometabolic signaling and DNA damage response is proposed to accelerate cardiovascular complications in systemic lupus erythematosus patients
NUAK2 silencing and inactivation of the PI3K pathway efficiently controlled CDK2 expression, whereas CDK2 inactivation specifically abrogated the growth of NUAK2-amplified and PTEN-deficient melanoma cells.
The AMPK (show PRKAA1 ELISA Kits)-related kinase SNARK regulates hepatitis C virus replication and pathogenesis through enhancement of TGF-beta (show TGFB1 ELISA Kits) signaling.
Activation of AMP-activated protein kinase (show PRKAA2 ELISA Kits) protects the integrity of the blood-brain barrier by suppressing the induction of NADPH oxidase (show NOX1 ELISA Kits)-derived superoxide anions.
Considers possible roles of NUAK2 in tumorigenesis in general and suggest that NUAK2 has pivotal roles in acral melanomagenesis.
MLCP (myosin light chain phosphatase) activation is counteracted by a previously unrecognized association between MRIP (myosin phosphatase Rho-interacting protein (show MPRIP ELISA Kits)) and the inducible kinase NUAK2
This study further supports the importance of NUAK2 in cancer development and tumor progression, while AMPK (show PRKAA1 ELISA Kits) has antioncogenic properties.
Data show that SNARK is activated by muscle contraction and is a unique mediator of contraction-stimulated glucose transport in skeletal muscle.
SNARK is an NF-kappaB (show NFKB1 ELISA Kits)-regulated anti-apoptotic gene that contributes to the tumor-promoting activity of CD95 (show FAS ELISA Kits) in apoptosis-resistant tumor cells
These findings reveal a critical role for SNARK in myocyte survival and the maintenance of muscle mass with age.
NUAK1 and NUAK2 complementarily function in the apical constriction and apico-basal elongation that associate with the dorsolateral hinge point formation in cephalic neural plate during the 5- to 10-somite stages.
Obesity was a risk factor for colorectal tumorigenesis in Snark(+/-) mice model.
Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95- activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1 (By similarity).
NUAK family SNF1-like kinase 2
, SNF1/AMP activated protein kinase
, SNF1/AMP kinase-related kinase
, omphalocele kinase 2
, SNF1/AMP-activated protein kinase