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Naf1 Proteins (TNIP1)

RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis.

list all proteins Gene Name GeneID UniProt
Mouse TNIP1 TNIP1 234344 Q3UMQ8
Human TNIP1 TNIP1 92345 Q96HR8
Rat TNIP1 TNIP1 306387 Q52KK4
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More Proteins for Naf1 (TNIP1) Interaction Partners

Mouse (Murine) Naf1 (TNIP1) interaction partners

  1. NAF-1, a BCL-2 (show BCL2 Proteins)-associated autophagy regulator, is required for homeostatic maintenance of skeletal muscle

Human Naf1 (TNIP1) interaction partners

  1. provides the first structural information, to our knowledge, for future targeting of the NAF-1-Bcl-2 (show BCL2 Proteins) complex in the regulation of apoptosis/autophagy in cancer biology

  2. NAF-1 as a previously unidentified cell target of anti-diabetes thiazolidinedione drugs.

  3. NAF-1 is a BCL-2 (show BCL2 Proteins)-associated co-factor that targets BCL-2 (show BCL2 Proteins) for antagonism of the autophagy pathway at the endoplasmic reticulum.

Naf1 (TNIP1) Protein Profile

Protein Summary

RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by NOLA1/GAR1 to yield mature H/ACA snoRNPs complex. Probably competes with NOLA1/GAR1 for binding with DKC1/NOLA4 (By similarity).

Gene names and symbols associated with Naf1 Proteins (TNIP1)

  • nuclear assembly factor 1 homolog (S. cerevisiae) (Naf1)
  • nuclear assembly factor 1 ribonucleoprotein (NAF1)
  • nuclear assembly factor 1 ribonucleoprotein (Naf1)
  • Gm174 protein
  • RGD1306802 protein

Protein level used designations for Naf1 Proteins (TNIP1)

H/ACA ribonucleoprotein complex non-core subunit NAF1 , nuclear assembly factor 1 homolog

GENE ID SPECIES
234344 Mus musculus
92345 Homo sapiens
306387 Rattus norvegicus
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