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Nardilysin (N-Arginine Dibasic Convertase) (NRD1) ELISA Kits

NRD1 encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. Additionally we are shipping NRD1 Antibodies (33) and NRD1 Proteins (2) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human NRD1 NRD1 4898 O43847
Anti-Rat NRD1 NRD1 25499 P47245
Anti-Mouse NRD1 NRD1 230598 Q8BHG1
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More ELISA Kits for NRD1 Interaction Partners

Human Nardilysin (N-Arginine Dibasic Convertase) (NRD1) interaction partners

  1. MRNA expression of NRD1 was upregulated in 56% of ESCC tissue samples.

  2. This study demonistrated that alcohol-dependent reduction of nardilysin in cell culture and nervous tissue points to an implication of the enzyme in the pathophysiology of alcoholism.

  3. possible roles of nardilysin in Alzheimer disease, Down syndrome, schizophrenia, mood disorders, alcohol abuse, heroin addiction and cancer; show that nardilysin is a Janus-faced enzyme with regard to brain pathology-- probably neuropathogenic in some diseases, but neuroprotective in others [review]

  4. SH-SY5Y cells, stably transfected with green fluorescent protein-tagged-p42 (show EPB42 ELISA Kits)(IP4) show enhanced NRD (show PRDM1 ELISA Kits) protein expression already at an earlier time point after retinoic acid stimulation.

  5. NRD1 interacts with p53 (show TP53 ELISA Kits) mutant R273H

  6. These results demonstrate that gastric cancer cell growth is maintained by autonomous TNF-alpha (show TNF ELISA Kits)-NF-kappaB (show NFKB1 ELISA Kits) and IL-6 (show IL6 ELISA Kits)-STAT3 (show STAT3 ELISA Kits) signalling, and that NRDc and ADAM proteases turn on these signalling cascades by stimulating ectodomain shedding of TNF-alpha (show TNF ELISA Kits).

  7. Identification and characterization of nardilysin as a novel dimethyl H3K4-binding protein involved in transcriptional regulation.

  8. Several flanking SNPs of the top hits in the meta-analysis demonstrated borderline associations with alcohol dependence in the family sample for KIAA0040, NRD1 and THSD7B, respectively.

  9. Tubulin (show TUBB ELISA Kits) potentiates the interaction of the metalloendopeptidase (show THOP1 ELISA Kits) nardilysin with the neuronal scaffold protein (show HOMER1 ELISA Kits) p42IP4 (show ADAP1 ELISA Kits)/centaurin-alpha1 (ADAP1 (show ADAP1 ELISA Kits)).

  10. nardilysin (NRDc) is potently inhibited by heparin-binding epidermal growth factor-like growth factor (HB-EGF (show HBEGF ELISA Kits))

Mouse (Murine) Nardilysin (N-Arginine Dibasic Convertase) (NRD1) interaction partners

  1. deletion of nardilysin prevents the development of diet-induced steatohepatitis and liver fibrogenesis

  2. Identification and characterization of nardilysin as a novel dimethyl H3K4-binding protein involved in transcriptional regulation.

  3. The use of proteolysis to study the structure of nardilysin.

  4. Studies extend the range of potential substrates for nardilysin and further substantiate that nardilysin is a true peptidase.

  5. miniglucagon-generating endopeptidase is composed of NRDc and aminopeptidase B (show RNPEP ELISA Kits) acting sequentially

  6. role for nardilysin in oocyte meiosis through its dynamic translocation from cytosol to nucleus, and then to the spindle apparatus

  7. NRDc regulates axonal maturation and myelination in the nervous system, in part, through the modulation of NRG1 (show NRG1 ELISA Kits) shedding

  8. The acidic stretch of nardilysin, expressed as a fusion protein with glutathione S-transferase (show GSTa2 ELISA Kits) and compared to the native enzyme with respect to spermine binding, functions as an autonomous domain.

NRD1 Antigen Profile

Antigen Summary

This gene encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. This protein interacts with heparin-binding EGF-like growth factor and plays a role in cell migration and proliferation. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with NRD1

  • nardilysin (N-arginine dibasic convertase) (NRD1) antibody
  • nardilysin (N-arginine dibasic convertase) (nrd1) antibody
  • nardilysin (CpipJ_CPIJ002524) antibody
  • nardilysin (Tsp_03755) antibody
  • nardilysin 1 (Nrd1) antibody
  • nardilysin, N-arginine dibasic convertase, NRD convertase 1 (Nrd1) antibody
  • 2600011I06Rik antibody
  • AI875733 antibody
  • DKFZp459N143 antibody
  • hNRD1 antibody
  • hNRD2 antibody
  • Nardilysin antibody
  • NRD-C antibody
  • NRD1 antibody
  • NRDC antibody
  • si:dkey-171o17.4 antibody

Protein level used designations for NRD1

nardilysin , nardilysin (N-arginine dibasic convertase) , NRD convertase , N-arginine dibasic convertase , NRD-C , N-arginine dibasic convertase 1 , nardilysin 1 (N-arginine dibasic convertase) , nardilysin, N-arginine dibasic convertase 1 , nardilysin, N-arginine dibasic convertase, NRD convertase 1

GENE ID SPECIES
424635 Gallus gallus
456852 Pan troglodytes
475354 Canis lupus familiaris
552055 Apis mellifera
557565 Danio rerio
6033791 Culex quinquefasciatus
10910482 Trichinella spiralis
100173985 Pongo abelii
100452780 Pongo abelii
100514906 Sus scrofa
4898 Homo sapiens
25499 Rattus norvegicus
230598 Mus musculus
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