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The protein encoded by NPPC is proteolytically processed to form a secreted hormone of the natriuretic peptide family. Additionally we are shipping Natriuretic Peptide Precursor C Kits (53) and Natriuretic Peptide Precursor C Antibodies (53) and many more products for this protein.
Showing 8 out of 9 products:
CNP (show CNP Proteins)/NPR-B (show NPR2 Proteins) can affect sperm motility and acrosome reaction, thus regulating the reproductive function of males
CNP (show CNP Proteins) levels rose after paroxysmal supraventricular tachycardia and continued to rise after the termination.
examined whether CNP reduces hyaluronan production and export via members of the multidrug resistance protein (MRP) and diminishes pro-inflammatory effects in chondrocytes
Plasma CNP (show CNP Proteins) might serve as a useful predictor for the therapeutic efficacy of metoprolol on postural tachycardia syndrome in children.
CNP (show CNP Proteins)/proCNP could be new markers in human prostate cancer
This case supports the concept that NPPC is overexpressed because of the loss of a specific negative regulatory control in the normal chromosomal location, and demonstrates the effectiveness of targeted resequencing in the mapping of breakpoints.
An increased level of NT-pro CNP (show CNP Proteins) is a promising non-invasive marker of hepatitis C related CLD (show SLC26A3 Proteins) complications and disease progression.
CNP (show CNP Proteins) effectively attenuated LPS (show IRF6 Proteins)-induced endothelial activation by inhibiting the NF-kappaB (show NFKB1 Proteins) and p38 (show CRK Proteins) signaling pathways.
In achondroplasia, hypochondroplasia, and thanatophoric dysplasia, elevated plasma levels of proCNP products suggest the presence of tissue resistance to CNP (show CNP Proteins).
Data indicate an important, previously neglected, role of NEP (show MME Proteins) for regulation of luminal factors in the epididymis and suggest a novel role for CNP (show CNP Proteins)/guanylyl cyclase B in the epididymal epithelium.
CNP and BNP serve as oocyte maturation inhibitor to inhibit oocyte maturation in mammals.
The first intron in the CNP sequence does not contain any additional enhancer-binding sites. However, the signal sequence is indispensable for secretion of CNP and its appropriate physiological function.
Inhibition of restenosis without compromising reendothelialization makes use of gene transfer into endothelial cells and muscle, smooth, vascular cells by administration of CNP.
Regional differences in BNP and CNP expression were observed in myocardium with sustained left ventricular dyssynchronous contraction.
Data suggest natriuretic peptide precursor C (NPPC) can regulate oogenesis/gap junction mediated communication between oocytes and cumulus cells; here, NPPC is used in non-pharmacological coordination of meiotic prophase in vitro oocyte maturation.
CNP (show CNP Proteins) activates bone turnover and remodeling in vivo and possibly accelerates fracture healing in a mouse model.
The up-to-day world-wide data about the structure, distribution, and physiological effects of the most poorly known among the natriuretic peptides--the C-type (CNP (show CNP Proteins))--are summarized in the review.
Connexin mimetics directed against connexin-43 (Cx43 (show GJA1 Proteins) CMP (show MATN1 Proteins)) overcame NPPC-mediated meiotic arrest in both isolated cumulus oocyte complexes and antral follicles.
CNP (show CNP Proteins)/NPR-C (show NPR3 Proteins) pathway has potential as a disease-modifying therapeutic target for cardiovascular disorders
Data indicate an important, previously neglected, role of NEP (show MME Proteins) for regulation of luminal factors in the epididymis and suggest a novel role for CNP (show CNP Proteins)/guanylyl cyclase B in the epididymal epithelium
CNP (show CNP Proteins) overexpression in chondrocytes can prevent endochondral growth delay and protect against cartilage damage in a mouse model of inflammatory arthritis.
Data suggest that intracerebroventricular administration of C-type natriuretic peptide (CNP-22 or CNP (show CNP Proteins)-53) has anorexigenic effect on hypothalamic neurons via activation of melanocortin/melanocortin receptor signal transduction.
CNP (show CNP Proteins)/NPR2 (show NPRL2 Proteins) signaling is essential for oocyte meiotic arrest in early antral follicles and activated LH/amphiregulin (show AREG Proteins)/EGFR (show EGFR Proteins) signaling pathway suppresses this signal by downregulating Nppc expression.
we show that CNP (show CNP Proteins) plays important region-specific roles in the GI tract of mice.
CNP (show CNP Proteins) secreted by growing follicles is capable of stimulating preantral and antral follicle growth
The protein encoded by this gene is proteolytically processed to form a secreted hormone of the natriuretic peptide family. The encoded hormone regulates the growth and differentiation of cartilaginous growth plate chondrocytes and may also be vasoactive and natriuretic.
C-type natriuretic peptide
, natriuretic peptide precursor C
, natriuretic peptide precursor type C
, C-type natriuretic peptide 3