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anti-Natriuretic Peptide Receptor A/guanylate Cyclase A (Atrionatriuretic Peptide Receptor A) (NPR1) Antibodies

Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms (Garbers and Lowe, 1994 [PubMed 7982997]). Additionally we are shipping NPR1 Kits (15) and NPR1 Proteins (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NPR1 18160 P18293
NPR1 4881 P16066
NPR1 24603 P18910
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Top anti-NPR1 Antibodies at antibodies-online.com

Showing 10 out of 82 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p) Immunofluorescence confocal photomicrograph of vertical sections of the rat retina, stained with anti-ANPA (NPR-A), ABIN392702. IF data courtesy of Dr. Essam Abdelalim, Shiga University of Medical Science. IF Immunostaining with anti-ANP and anti-human lamin antibodies revealed the presence of lamin-positive human ES cell derived-cardiomyocytes (Fig. 4A). (Stem Cells 2007 Sep 01.25(9):2200-2205) 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IF 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$588.50
Details
Mouse Rabbit Un-conjugated IHC (p), WB Mouse Npr1 Antibody (N-term) (ABIN657994) western blot analysis in mouse heart tissue lysates (35 µg/lane). This demonstrates the Npr1 antibody detected the Npr1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Biotin ICC, IHC, ELISA   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB   20 μL Log in to see 4 to 5 Days
$221.47
Details
Human Rabbit Un-conjugated IHC 400 μL Log in to see 6 Days
$457.14
Details
Human Mouse Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated IHC (p), WB   20 μL Log in to see 8 to 10 Days
$566.50
Details

NPR1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-NPR1 Antibodies

  1. Human Polyclonal NPR1 Primary Antibody for IHC (p) - ABIN392702 : Takahashi, Nakayama, Soma, Izumi, Kanmatsuse: Organization of the human natriuretic peptide receptor A gene. in Biochemical and biophysical research communications 1998 (PubMed)
    Show all 4 references for ABIN392702

  2. Human Polyclonal NPR1 Primary Antibody for EIA, IF - ABIN360587 : Dams, Van Acker, Gustin, Vereycken, Bunkens, Holemans, Smeulders, Clayton, Ohagen, Hertogs: A time-resolved fluorescence assay to identify small-molecule inhibitors of HIV-1 fusion. in Journal of biomolecular screening 2007 (PubMed)
    Show all 2 references for ABIN360587

  3. Human Polyclonal NPR1 Primary Antibody for IF, IHC (p) - ABIN191702 : Hirsch, Kruhøffer, Adermann, Heitland, Maronde, Meyer, Forssmann, Herter, Plenz, Schlatter: Cellular localization, membrane distribution, and possible function of guanylyl cyclases A and 1 in collecting ducts of rat. in Cardiovascular research 2001 (PubMed)

More Antibodies against NPR1 Interaction Partners

Mouse (Murine) Natriuretic Peptide Receptor A/guanylate Cyclase A (Atrionatriuretic Peptide Receptor A) (NPR1) interaction partners

  1. Conclude that postnatal cardiac hyperplasia in mice with global GC-A (show GUCA1A Antibodies) inactivation is provoked by systemic alterations rather than direct regulation of cardiac myocyte proliferation.

  2. Data (including data from studies in knockout mice) suggest expression of ANP (show NPPA Antibodies)/BNP (show BNC2 Antibodies)/GC-A (show GUCA1A Antibodies) (atrial natriuretic peptide (show NPPA Antibodies), brain natriuretic peptide (show BNP Antibodies), and guanylyl cyclase-A) is important in embryonic neovascularization and organogenesis.

  3. Suggest that the FQQI motif is essential for the internalization and subcellular trafficking of NPRA during the hormone signaling process in intact mesangial cells.

  4. Data suggest activation of skeletal muscle (SM) Npra is important for maintenance of long-ter (show INS Antibodies)m insulin sensitivity; up-regulation of Npra signal transduction in SM (that was reduced by obesity) prevents glucose intolerance and diabetes type 2.

  5. these findings define a novel epigenetic regulatory mechanism that governs Npr1 gene transcription.

  6. Npr1 represses the expression of cardiac proinflammatory mediators, hypertrophic markers, and NF-kappaB/AP-1-mediated mechanisms, which seem to be associated in an Npr1 gene-dose-dependent manner

  7. ANP (show NPPA Antibodies) is capable of attenuating agonist-induced lung edema in the absence of NPR-A.

  8. These results demonstrate that a high-salt diet aggravates cardiac ANG II, aldosterone and pro-inflammatory cytokine levels in Npr1 gene-disrupted 1-copy mice, whereas, in Npr1 gene-duplicated (3-copy and 4-copy) mice, high salt did not render such elevation, suggesting the potential roles of Npr1 against salt loading.

  9. ANP (show NPPA Antibodies)-NPRA system exerts an inhibitory effect on MAPKs and down-stream effector molecules, AP-1 (show JUN Antibodies), and CREB (show CREB1 Antibodies), critical for cell growth and proliferation.

  10. Natriuretic peptide receptor guanylyl cyclase-A protects podocytes from aldosterone-induced glomerular injury.

Human Natriuretic Peptide Receptor A/guanylate Cyclase A (Atrionatriuretic Peptide Receptor A) (NPR1) interaction partners

  1. After ligand binding, NPRA is rapidly internalized and trafficked from the cell surface into endosomes, Res and lysosomes, with concurrent generation of intracellular cyclic GMP (show NT5C2 Antibodies) in HEK (show EPHA3 Antibodies)-293 cells.

  2. Data suggest up-regulation of NPRA in skeletal muscle (SM) correlates with whole-body insulin (show INS Antibodies) sensitivity; NPRA is down-regulated in SM in obese subjects compared to normal controls; NPRA in SM is up-regulated in response to diet-induced weight loss.

  3. In this review we highlight the mechanisms by which NPR-A affects signaling pathways involved in inflammation and cancer, and we discuss its potential as a novel target in inflammation, cancer, and cancer-related inflammation

  4. NPRA was detected in E11.5 cardiac progenitor cells.

  5. Cardiac fibrosis and the endogenous natriuretic peptide system were evaluated in end-stage heart failure to assess the anti-fibrotic actions of the dual GC-A/-B activator.

  6. High NPR1 expression is associated with esophageal squamous cell carcinomas.

  7. Molecular dynamics analysis indicated decreases in the values of Van (show TNIP1 Antibodies) der (show GDF3 Antibodies) Waals, electrostatic energy and potential energy of NPRB (show NPR2 Antibodies)/Vasonatrin peptide compared to NPRA/Vasonatrin peptide.

  8. ACNP stimulated both human natriuretic peptide receptors (NPRs), NPRA and NPRB (show NPR2 Antibodies), as potent as their native ligands in receptor transfected cells.

  9. human ventricular cardiomyocytes express low levels of GC-A and GC-A in cardiomyocytes from failing human hearts is refractory to ANP (show NPPA Antibodies) stimulation.

  10. Results demonstrate the opposite effects of NPR-A and NPR-C (show NPR3 Antibodies) in LPS (show IRF6 Antibodies)-mediated endothelial permeability and lung injury.

NPR1 Antigen Profile

Protein Summary

Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms (Garbers and Lowe, 1994

Gene names and symbols associated with NPR1

  • natriuretic peptide receptor 1a (npr1a) antibody
  • natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) (NPR1) antibody
  • natriuretic peptide receptor 1 (Npr1) antibody
  • natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) (Npr1) antibody
  • AI893888 antibody
  • ANPa antibody
  • Anpra antibody
  • GC-A antibody
  • Gca antibody
  • GUC2A antibody
  • GUCY2A antibody
  • NPR-A antibody
  • Npra antibody
  • Pndr antibody
  • sGC antibody
  • si:dkey-27c15.1 antibody

Protein level used designations for NPR1

aatriuretic peptide receptor A , atrial natriuretic peptide receptor 1 , guanylyl cyclase beta 1, soluable , natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) , natriuretic peptide receptor 1 , ANP-A , ANPR-A , Nppa receptor , atrial natriuretic peptide receptor type A , guanylate cyclase A , guanylyl cyclase-A , GC-A , NPR-A , atrionatriuretic peptide receptor A , natriuretic peptide A type receptor , natriuretic peptide receptor A , atrial natriuretic peptide A-type receptor , atrial natriuretic peptide receptor A

GENE ID SPECIES
560653 Danio rerio
100343663 Oryctolagus cuniculus
18160 Mus musculus
4881 Homo sapiens
24603 Rattus norvegicus
Selected quality suppliers for anti-NPR1 (NPR1) Antibodies
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