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Natriuretic Peptide Receptor A/guanylate Cyclase A (Atrionatriuretic Peptide Receptor A) Proteins (NPR1)

Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms (Garbers and Lowe, 1994 [PubMed 7982997]). Additionally we are shipping NPR1 Antibodies (82) and NPR1 Kits (15) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NPR1 18160 P18293
NPR1 4881 P16066
NPR1 24603 P18910
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Top NPR1 Proteins at antibodies-online.com

Showing 10 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 69 to 74 Days
$9,050.32
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 69 to 74 Days
$12,906.52
Details
Yeast Human His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,234.00
Details
HOST_Baculovirus infected Insect Cells Human GST tag   50 μg Log in to see 10 to 12 Days
$570.24
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

NPR1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , , , , ,
, , ,
Rat (Rattus)

More Proteins for Natriuretic Peptide Receptor A/guanylate Cyclase A (Atrionatriuretic Peptide Receptor A) (NPR1) Interaction Partners

Mouse (Murine) Natriuretic Peptide Receptor A/guanylate Cyclase A (Atrionatriuretic Peptide Receptor A) (NPR1) interaction partners

  1. Conclude that postnatal cardiac hyperplasia in mice with global GC-A (show GUCA1A Proteins) inactivation is provoked by systemic alterations rather than direct regulation of cardiac myocyte proliferation.

  2. Data (including data from studies in knockout mice) suggest expression of ANP (show NPPA Proteins)/BNP/GC-A (show GUCA1A Proteins) (atrial natriuretic peptide (show NPPA Proteins), brain natriuretic peptide (show BNP Proteins), and guanylyl cyclase-A) is important in embryonic neovascularization and organogenesis.

  3. Suggest that the FQQI motif is essential for the internalization and subcellular trafficking of NPRA during the hormone signaling process in intact mesangial cells.

  4. Data suggest activation of skeletal muscle (SM) Npra is important for maintenance of long-ter (show INS Proteins)m insulin sensitivity; up-regulation of Npra signal transduction in SM (that was reduced by obesity) prevents glucose intolerance and diabetes type 2.

  5. these findings define a novel epigenetic regulatory mechanism that governs Npr1 gene transcription.

  6. Npr1 represses the expression of cardiac proinflammatory mediators, hypertrophic markers, and NF-kappaB/AP-1-mediated mechanisms, which seem to be associated in an Npr1 gene-dose-dependent manner

  7. ANP (show NPPA Proteins) is capable of attenuating agonist-induced lung edema in the absence of NPR-A.

  8. These results demonstrate that a high-salt diet aggravates cardiac ANG II, aldosterone and pro-inflammatory cytokine levels in Npr1 gene-disrupted 1-copy mice, whereas, in Npr1 gene-duplicated (3-copy and 4-copy) mice, high salt did not render such elevation, suggesting the potential roles of Npr1 against salt loading.

  9. ANP (show NPPA Proteins)-NPRA system exerts an inhibitory effect on MAPKs and down-stream effector molecules, AP-1 (show JUN Proteins), and CREB (show CREB1 Proteins), critical for cell growth and proliferation.

  10. Natriuretic peptide receptor guanylyl cyclase-A protects podocytes from aldosterone-induced glomerular injury.

Human Natriuretic Peptide Receptor A/guanylate Cyclase A (Atrionatriuretic Peptide Receptor A) (NPR1) interaction partners

  1. After ligand binding, NPRA is rapidly internalized and trafficked from the cell surface into endosomes, Res and lysosomes, with concurrent generation of intracellular cyclic GMP (show NT5C2 Proteins) in HEK (show EPHA3 Proteins)-293 cells.

  2. Data suggest up-regulation of NPRA in skeletal muscle (SM) correlates with whole-body insulin (show INS Proteins) sensitivity; NPRA is down-regulated in SM in obese subjects compared to normal controls; NPRA in SM is up-regulated in response to diet-induced weight loss.

  3. In this review we highlight the mechanisms by which NPR-A affects signaling pathways involved in inflammation and cancer, and we discuss its potential as a novel target in inflammation, cancer, and cancer-related inflammation

  4. NPRA was detected in E11.5 cardiac progenitor cells.

  5. Cardiac fibrosis and the endogenous natriuretic peptide system were evaluated in end-stage heart failure to assess the anti-fibrotic actions of the dual GC-A/-B activator.

  6. High NPR1 expression is associated with esophageal squamous cell carcinomas.

  7. Molecular dynamics analysis indicated decreases in the values of Van (show TNIP1 Proteins) der (show GDF3 Proteins) Waals, electrostatic energy and potential energy of NPRB (show NPR2 Proteins)/Vasonatrin peptide compared to NPRA/Vasonatrin peptide.

  8. ACNP stimulated both human natriuretic peptide receptors (NPRs), NPRA and NPRB (show NPR2 Proteins), as potent as their native ligands in receptor transfected cells.

  9. human ventricular cardiomyocytes express low levels of GC-A and GC-A in cardiomyocytes from failing human hearts is refractory to ANP (show NPPA Proteins) stimulation.

  10. Results demonstrate the opposite effects of NPR-A and NPR-C (show NPR3 Proteins) in LPS (show IRF6 Proteins)-mediated endothelial permeability and lung injury.

NPR1 Protein Profile

Protein Summary

Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms (Garbers and Lowe, 1994

Gene names and symbols associated with NPR1

  • natriuretic peptide receptor 1a (npr1a)
  • natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) (NPR1)
  • natriuretic peptide receptor 1 (Npr1)
  • natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) (Npr1)
  • AI893888 protein
  • ANPa protein
  • Anpra protein
  • GC-A protein
  • Gca protein
  • GUC2A protein
  • GUCY2A protein
  • NPR-A protein
  • Npra protein
  • Pndr protein
  • sGC protein
  • si:dkey-27c15.1 protein

Protein level used designations for NPR1

aatriuretic peptide receptor A , atrial natriuretic peptide receptor 1 , guanylyl cyclase beta 1, soluable , natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) , natriuretic peptide receptor 1 , ANP-A , ANPR-A , Nppa receptor , atrial natriuretic peptide receptor type A , guanylate cyclase A , guanylyl cyclase-A , GC-A , NPR-A , atrionatriuretic peptide receptor A , natriuretic peptide A type receptor , natriuretic peptide receptor A , atrial natriuretic peptide A-type receptor , atrial natriuretic peptide receptor A

GENE ID SPECIES
560653 Danio rerio
100343663 Oryctolagus cuniculus
18160 Mus musculus
4881 Homo sapiens
24603 Rattus norvegicus
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