You are viewing an incomplete version of our website. Please click to reload the website as full version.

Nebulette Proteins (NEBL)

NEBL encodes a nebulin like protein that is abundantly expressed in cardiac muscle. Additionally we are shipping Nebulette Antibodies (28) and Nebulette Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat NEBL NEBL 307189  
NEBL 10529 O76041
NEBL 74103 Q9DC07
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Nebulette Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

NEBL Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

More Proteins for Nebulette (NEBL) Interaction Partners

Human Nebulette (NEBL) interaction partners

  1. predisposition to multibacillary leprosy in Vietnam is associated with CUBN (show CUBN Proteins) and NEBL common variants in the chromosome 10p13 linkage region

  2. We identify the SH3 domains of nebulin and nebulette as novel ligands of proline-rich regions of Xin and XIRP2

  3. Data indicate that lasp-2 interacts with the focal adhesion proteins vinculin (show VCL Proteins) and paxillin (show PXN Proteins).

  4. Report oncogenic potential of MLL (show MLL Proteins)-NEBL and NEBL-MLL (show MLL Proteins) fusion genes in acute myeloid leukemia (show BCL11A Proteins).

  5. Different mutations in nebulette transgene trigger a pathological cascade leading to endocardial fibroelastosis and dilated cardiomyopathy in mutant embryonic mouse hearts.

  6. our data demonstrate the importance of this cardiac-specific nebulin isoform in myofibril organization and function. Our data demonstrate that nebulette plays a significant role in the structure and stability of the cardiac Z-line.

  7. LIM-nebulette, Lasp-1 (show LASP1 Proteins), and zyxin (show ZYX Proteins) may play an important role in the organization of focal adhesions

  8. filamin-C (show FLNC Proteins), a known component of striated (show NSDHL Proteins) muscle Z-lines, interacts with nebulette modules

  9. the importance of the nebulette-TPM (show TPMT Proteins) interactions in the maintenance and stability of the thin filaments.

Mouse (Murine) Nebulette (NEBL) interaction partners

  1. the nebulette disease causing mutations have dominant gain-of-function effects

  2. This study showed distinct effects of NEBL mutations on sarcomere ultrastructure, cellular contractile function, and calcium homeostasis in preclinical DCM in vivo.

  3. Actin filament binding activity may be a major contributor to the subcellular localization of lasp-2 to filopodia but is not crucial for lasp-2 recruitment to focal adhesions [lasp-2]

  4. LIM-nebulette, Lasp-1 (show LASP1 Proteins), and zyxin (show ZYX Proteins) may play an important role in the organization of focal adhesions [LIM-nebulette]

Nebulette (NEBL) Protein Profile

Protein Summary

This gene encodes a nebulin like protein that is abundantly expressed in cardiac muscle. The encoded protein binds actin and interacts with thin filaments and Z-line associated proteins in striated muscle. This protein may be involved in cardiac myofibril assembly. A shorter isoform of this protein termed LIM nebulette is expressed in non-muscle cells and may function as a component of focal adhesion complexes. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with Nebulette Proteins (NEBL)

  • nebulette (Nebl)
  • nebulette (NEBL)
  • nebulette (nebl)
  • 1200007O21Rik protein
  • A630080F05Rik protein
  • BB140644 protein
  • D830029A09Rik protein
  • LASP-2 protein
  • LASP2 protein
  • Lnebl protein
  • zgc:113144 protein

Protein level used designations for Nebulette Proteins (NEBL)

LIM and SH3 protein , nebulette , LIM-nebulette , actin-binding Z-disk protein

GENE ID SPECIES
307189 Rattus norvegicus
395148 Gallus gallus
517987 Bos taurus
541446 Danio rerio
702764 Macaca mulatta
740056 Pan troglodytes
100019946 Monodelphis domestica
100055848 Equus caballus
100078834 Ornithorhynchus anatinus
100127275 Xenopus laevis
100343234 Oryctolagus cuniculus
100414047 Callithrix jacchus
100454212 Pongo abelii
100463626 Ailuropoda melanoleuca
100496676 Xenopus (Silurana) tropicalis
100522395 Sus scrofa
100551611 Anolis carolinensis
100582784 Nomascus leucogenys
10529 Homo sapiens
74103 Mus musculus
477974 Canis lupus familiaris
Selected quality suppliers for Nebulette Proteins (NEBL)
Did you look for something else?