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anti-Neighbor of BRCA1 Gene 1 (NBR1) Antibodies

The protein encoded by NBR1 was originally identified as an ovarian tumor antigen monitored in ovarian cancer. Additionally we are shipping Neighbor of BRCA1 Gene 1 Kits (4) and Neighbor of BRCA1 Gene 1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NBR1 4077 Q14596
NBR1 17966 P97432
NBR1 303554 Q501R9
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Top anti-Neighbor of BRCA1 Gene 1 Antibodies at antibodies-online.com

Showing 10 out of 39 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated WB NBR1 monoclonal antibody (M01), clone 6B11. Western Blot analysis of NBR1 expression in PC-12. Detection limit for recombinant GST tagged NBR1 is approximately 0.1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-Nbr1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Mouse Spleen WB Suggested Anti-Nbr1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: Mouse Spleen 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged NBR1 is approximately 0.1ng/ml as a capture antibody. Western Blot detection against Immunogen (36.19 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (36.56 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Mouse Un-conjugated WB Western Blot analysis of NBR1 expression in transfected 293T cell line by NBR1 MaxPab polyclonal antibody.Lane 1: NBR1 transfected lysate(106.26 KDa).Lane 2: Non-transfected lysate. 50 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IF, WB 100 μL Log in to see 14 Days
$527.15
Details
Human Rabbit Un-conjugated WB Western Blot analysis of NBR1 expression in transfected 293T cell line by NBR1 MaxPab polyclonal antibody.Lane 1: NBR1 transfected lysate(107.40 KDa).Lane 2: Non-transfected lysate. 100 μL Log in to see 9 Days
$418.57
Details
Human Mouse Un-conjugated RNAi, ELISA, WB Western blot analysis of NBR1 over-expressed 293 cell line, cotransfected with NBR1 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with NBR1 monoclonal antibody (M05), clone 5C3. GAPDH ( 36.1 kDa ) used as specificity and loading control. Detection limit for recombinant GST tagged NBR1 is approximately 0.03ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB Nbr1 antibody used at 0.2-1 ug/ml to detect target protein. 50 μg Log in to see 7 to 9 Days
$473.93
Details
Human Rabbit Un-conjugated IHC   50 μL Log in to see 8 to 10 Days
$463.83
Details

NBR1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
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Mouse (Murine) ,


Rat (Rattus)


Top referenced anti-Neighbor of BRCA1 Gene 1 Antibodies

  1. Human Monoclonal NBR1 Primary Antibody for ELISA, WB - ABIN517601 : Mardakheh, Yekezare, Machesky, Heath: Spred2 interaction with the late endosomal protein NBR1 down-regulates fibroblast growth factor receptor signaling. in The Journal of cell biology 2009 (PubMed)
    Show all 7 references for ABIN517601

  2. Human Monoclonal NBR1 Primary Antibody for WB - ABIN396674 : Rose, Behm, Drgon, Johnson, Uhl: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. in Molecular medicine (Cambridge, Mass.) 2010 (PubMed)
    Show all 5 references for ABIN396674

  3. Human Polyclonal NBR1 Primary Antibody for WB - ABIN517599 : Kuo, Chen, Baron, Onder, Loewer, Almeida, Weismann, Xu, Houghton, Gao, Daley, Doxsey: Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity. in Nature cell biology 2011 (PubMed)
    Show all 2 references for ABIN517599

  4. Human Polyclonal NBR1 Primary Antibody for ELISA, WB - ABIN517598 : Mostowy, Sancho-Shimizu, Hamon, Simeone, Brosch, Johansen, Cossart: p62 and NDP52 proteins target intracytosolic Shigella and Listeria to different autophagy pathways. in The Journal of biological chemistry 2011 (PubMed)

More Antibodies against Neighbor of BRCA1 Gene 1 Interaction Partners

Human Neighbor of BRCA1 Gene 1 (NBR1) interaction partners

  1. NBR1 is not required for PARK2 (show PARK2 Antibodies)-dependent mitophagy.

  2. The NBR1 depletion impairs FA turnover and decreases targeting of autophagosomes to FAs (show FAS Antibodies), whereas ectopic expression of autophagy-competent, but not autophagy-defective, NBR1 enhances FA disassembly and reduces FA lifetime during migration.

  3. NBR1 positively correlates with adipose inflammation in human obese patients. (show MAP3K3 Antibodies)

  4. Analysis of muscle biopsies (show GSK3b Antibodies)of sporadic inclusion body myositis (sIBM) patients revealed a strong decrease of NBR1 phosphorylation in muscles of sIBM patients that directly correlated with the severity of protein aggregation.

  5. The C-terminal fragments of SQSTM1 and NBR1 exhibited a dominant-negative effect against native SQSTM1/NBR1, probably by competing for LC3 and ubiquitin chain binding.

  6. structure of the ubiquitin-associated (UBA) domain of human autophagy receptor NBR1 and its interaction with ubiquitin and polyubiquitin (show UBB Antibodies)

  7. results suggest that NBR1 is the specific autophagy receptor for pexophagy.

  8. These findings suggest that NBR1 is involved in the formation of cytoplasmic inclusions in alpha-synucleinopathy.

  9. The structural ensemble representing each of the two sequential folding transition transition states of the PB1 (show SMR3A Antibodies) domain of NBR1 has been calculated using experimental Phi values and biased molecular dynamics simulations.

  10. Autophagy-related NBR1 protein is not involved in the formation/degradation of neuronal intranuclear inclusions in neurodegenerative diseases.

Mouse (Murine) Neighbor of BRCA1 Gene 1 (NBR1) interaction partners

  1. NBR1 is increased in adipose tissue macrophages in obese mice. The NBR1-MEKK3 (show MAP3K3 Antibodies) complex is important in JNK (show MAPK8 Antibodies) activation in macrophages.

  2. NBR1 phosphorylation by GSK3 (show GSK3b Antibodies) at Thr586 prevents the aggregation of ubiquitinated proteins and their selective autophagic degradation.

  3. In a mouse model of Huntington disease (show HTT Antibodies), NBR1 protein levels were decreased in all brain regions analyzed early in the disease, whereas at late stages they accumulated in the striatum and hippocampus, but not in the cortex.

  4. MURF2 (show TRIM55 Antibodies) expression parallels that of the autophagy-associated proteins LC3 (show MAP1LC3A Antibodies), p62/SQSTM1 (show SQSTM1 Antibodies) and nbr1

  5. Results define Nbr1 as a negative regulator of ligand-mediated receptor tyrosine kinase (show ERBB3 Antibodies) degradation and reveal the interplay between its various regions for protein localization and function.

  6. NBR1 is a novel PB1 (show GPR97 Antibodies) adapter in Th2 differentiation and asthma.

  7. might contribute to the metastasis of ovarian cancer to the peritoneum by initiating cell attachment to the mesothelial epithelium via binding to mesothelin (show MSLN Antibodies)

  8. The nbr1 UBA domain binds to lysine-48 and -63 linked polyubiquitin-B (show UBB Antibodies) chains. Nbr1 also binds to the autophagic effector protein LC3 (show MAP1LC3A Antibodies)-A via a novel binding site.

  9. findings suggest a critical function for NBR1 in the regulation of receptor trafficking and provide a mechanism for down-regulation of signaling by Spred2 (show SPRED2 Antibodies) via NBR1.

Neighbor of BRCA1 Gene 1 (NBR1) Antigen Profile

Protein Summary

The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled coil motif, which is present in many genes with transformation potential, but the function of this protein is unknown. This gene is located on a region of chromosome 17q21.1 that is in close proximity to tumor suppressor gene BRCA1. Three alternatively spliced variants encoding the same protein have been identified for this gene.

Gene names and symbols associated with NBR1

  • neighbor of brca1 gene 1 (nbr1) antibody
  • neighbor of BRCA1 gene 1 (nbr1) antibody
  • neighbor of BRCA1 gene 1 (NBR1) antibody
  • neighbor of BRCA1 gene 1 (LOC100354979) antibody
  • neighbor of Brca1 gene 1 (Nbr1) antibody
  • 1A1-3B antibody
  • Ca125 antibody
  • fa99f08 antibody
  • M17S2 antibody
  • MGC69008 antibody
  • mKIAA0049 antibody
  • NBR1 antibody
  • RGD1311421 antibody
  • wu:fa99f08 antibody

Protein level used designations for NBR1

neighbor of BRCA1 gene 1 , next to BRCA1 gene 1 protein , next to BRCA1 gene 1 protein-like , cell migration-inducing gene 19 protein , membrane component chromosome 17 surface marker 2 , membrane component, chromosome 17, surface marker 2 (ovarian carcinoma antigen CA125) , migration-inducing protein 19 , neighbor of BRCA1 gene 1 protein , protein 1A1-3B , membrane component chromosome 17 surface marker 2 homolog , next to the Brca1 , ovarian carcinoma antigen CA125

GENE ID SPECIES
337168 Danio rerio
379658 Xenopus laevis
420007 Gallus gallus
455047 Pan troglodytes
480509 Canis lupus familiaris
515032 Bos taurus
100051928 Equus caballus
100354979 Oryctolagus cuniculus
100393407 Callithrix jacchus
100581568 Nomascus leucogenys
100625110 Sus scrofa
4077 Homo sapiens
17966 Mus musculus
303554 Rattus norvegicus
100174370 Pongo abelii
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