You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Nephronophthisis 3 (Adolescent) (NPHP3) Antibodies

NPHP3 encodes a protein containing a coiled-coil (CC) domain, a tubulin-tyrosine ligase (TTL) domain, and a tetratrico peptide repeat (TPR) domain. Additionally we are shipping NPHP3 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NPHP3 27031 Q7Z494
NPHP3 74025 Q7TNH6
Anti-Rat NPHP3 NPHP3 363126  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-NPHP3 Antibodies at antibodies-online.com

Showing 10 out of 22 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB NPHP3 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of NPHP3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. NPHP3 Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35µg/lane).This demonstrates the NPHP3 antibody detected the NPHP3 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB NPHP3 Antibody (N-term)  western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the NPHP3 antibody detected the NPHP3 protein (arrow). NPHP3 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of NPHP3 Antibody (N-term) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit APC IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Mouse Un-conjugated ELISA, WB NPHP3 monoclonal antibody (M05), clone 3B1. Western Blot analysis of NPHP3 expression in HepG2. Detection limit for recombinant GST tagged NPHP3 is 3 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit HRP IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   200 μL Log in to see 11 to 16 Days
$532.71
Details
Human Rabbit FITC IHC, ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit APC IHC, ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details

NPHP3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
,
,
, , , , ,
Mouse (Murine)


Top referenced anti-NPHP3 Antibodies

  1. Human Polyclonal NPHP3 Primary Antibody for EIA, WB - ABIN953650 : Simpson, Cross, Cross, Helmuth, Crosby: Lethal cystic kidney disease in Amish neonates associated with homozygous nonsense mutation of NPHP3. in American journal of kidney diseases : the official journal of the National Kidney Foundation 2009 (PubMed)
    Show all 3 references for ABIN953650

More Antibodies against NPHP3 Interaction Partners

Human Nephronophthisis 3 (Adolescent) (NPHP3) interaction partners

  1. a rare neonatal ciliopathy presentation of NPHP3 mutations leading to severe multiorgan failure in two siblings.

  2. The known phenotype of NPHP3 mutation caused renal-hepatic-pancreatic dysplasia has been extended to include skeletal and CNS anomalies.

  3. ANKS6 (show ANKS6 Antibodies) as a new NPHP family member that assembles a distinct module of nephronophthisis-associated proteins, encompassing NEK8 (show NEK9 Antibodies), INVS (show INVS Antibodies) and NPHP3.

  4. Mutations in a novel gene, NPHP3, cause adolescent nephronophthisis, tapeto-retinal degeneration and hepatic fibrosis.

  5. In six families with nephronophthisis, there were two mutations in either NPHP1 (show NPHP1 Antibodies), NPHP3, or NPHP4 (show NPHP4 Antibodies), suggesting oligogenicity.

  6. NPHP3 mutations can cause a broad clinical spectrum of early embryonic patterning defects.

  7. screened 43 families with infantile nephronophthisis (ESRD less than 5 years of age) for NPHP2 (show INVS Antibodies) and NPHP3 mutations and determined genotype-phenotype correlations

  8. The presence of congenital malformations in the case series confirms the crucial role of NPHP3 in early embryonic development of the kidneys and urinary tract.

Mouse (Murine) Nephronophthisis 3 (Adolescent) (NPHP3) interaction partners

  1. Inv (show INVS Antibodies) acts as a molecular anchor for Nphp3 and Nek8 (show NEK8 Antibodies) in the proximal segment of primary cilia.

  2. a homozygous missense mutation in Nphp3 is probably responsible for the polycystic kidney disease (pcy) mouse phenotype

  3. The pcy mutation generates a hypomorphic Nphp3 allele that is responsible for the cystic kidney disease phenotype, whereas complete loss of Nphp3 function results in situs inversus, congenital heart defects, and embryonic lethality in mice.

NPHP3 Antigen Profile

Protein Summary

This gene encodes a protein containing a coiled-coil (CC) domain, a tubulin-tyrosine ligase (TTL) domain, and a tetratrico peptide repeat (TPR) domain. The encoded protein interacts with nephrocystin, it is required for normal ciliary development, and it functions in renal tubular development. Mutations in this gene are associated with nephronophthisis type 3, and also with renal-hepatic-pancreatic dysplasia, and Meckel syndrome type 7. Naturally occurring read-through transcripts exist between this gene and the downstream ACAD11 (acyl-CoA dehydrogenase family, member 11) gene.

Gene names and symbols associated with NPHP3

  • nephronophthisis 3 (nphp3) antibody
  • nephronophthisis 3 (adolescent) (NPHP3) antibody
  • nephronophthisis 3 (adolescent) (Nphp3) antibody
  • 3632410F03Rik antibody
  • AI550417 antibody
  • C230078J01 antibody
  • D330020E01Rik antibody
  • MKS7 antibody
  • NPH3 antibody
  • pcy antibody
  • RGD1563856 antibody
  • RHPD antibody
  • si:dkey-56l10.1 antibody

Protein level used designations for NPHP3

nephrocystin-3 , nephronophthisis 3 (adolescent) , Meckel syndrome, type 7

GENE ID SPECIES
562601 Danio rerio
27031 Homo sapiens
74025 Mus musculus
363126 Rattus norvegicus
Selected quality suppliers for anti-NPHP3 (NPHP3) Antibodies
Did you look for something else?