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anti-Nephronophthisis 4 (NPHP4) Antibodies

NPHP4 encodes a protein involved in renal tubular development and function. Additionally we are shipping NPHP4 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NPHP4 261734 O75161
NPHP4 313749  
NPHP4 260305 P59240
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Top anti-NPHP4 Antibodies at antibodies-online.com

Showing 10 out of 18 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain, using NPHP4 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated EIA, IHC (p) Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Mouse Un-conjugated ELISA   200 μL Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC (p), ELISA 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC, ELISA 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated ELISA, IHC   100 μL Log in to see 14 Days
$201.19
Details
Human Rabbit Un-conjugated IF, ELISA   50 μL Log in to see 9 to 11 Days
$313.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA   50 μg Log in to see 11 to 13 Days
$541.80
Details
Human Mouse Un-conjugated ELISA   200 μL Log in to see 11 to 16 Days
$553.14
Details
Human Rabbit Un-conjugated ELISA, IHC (p)   50 μg Log in to see 8 to 11 Days
$465.94
Details

NPHP4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , ,
,
,
Rat (Rattus)


Mouse (Murine) ,


Top referenced anti-NPHP4 Antibodies

  1. Human Monoclonal NPHP4 Primary Antibody for ELISA - ABIN531504 : Murga-Zamalloa, Desai, Hildebrandt, Khanna: Interaction of ciliary disease protein retinitis pigmentosa GTPase regulator with nephronophthisis-associated proteins in mammalian retinas. in Molecular vision 2010 (PubMed)

More Antibodies against NPHP4 Interaction Partners

Cow (Bovine) Nephronophthisis 4 (NPHP4) interaction partners

  1. retinitis pigmentosa GTPase regulator interacting protein 1 (show RPGRIP1 Antibodies) and nephrocystin-4 interact strongly in vitro and in vivo, and that they colocalize in the retina

Human Nephronophthisis 4 (NPHP4) interaction partners

  1. homozygous NPHP4 truncating mutation that expands the phenotypic spectrum of NPHP4-related nephronophthisis to also include cerebello-oculo-renal syndrome and abnormal spermatogenesis causing male infertility

  2. The ciliary protein nephrocystin-4 translocates the canonical Wnt (show WNT2 Antibodies) regulator Jade-1 (show PHF17 Antibodies) to the nucleus to negatively regulate beta-catenin (show CTNNB1 Antibodies) signaling.

  3. NPHP4 mutations are associated with cardiac laterality defects and heterotaxy.

  4. Identify NPHP4 as a negative regulator of the Hippo pathway and suggest that NPHP4 regulates cell proliferation through its effects on Hippo signaling.

  5. These results indicate the novel and independent association between single-point SNP rs1287637 in NPHP4 gene and renal function in non-diabetic Japanese population.

  6. Recessive mutations in the NPHP4 gene, encoding the protein nephroretinin, in humans cause nephronophthisis type 4 and Senior-Loken syndrome.There is evolutionary conservation of the NPHP4 gene, with an ortholog in C. elegans.

  7. Interacts with NPHP1 (show NPHP1 Antibodies) protein, suggesting that these two proteins participate in a common signaling pathway; identification of five different mutations in unrelated individuals with nephronophthisis

  8. part of multifunctional complex localized in actin- and microtubule-based structures

  9. two recessive mutations in NPHP4 are a rare cause of nephronophthisis, and single heterozygous NPHP4 sequence variants are three times more prevalent than two recessive mutations

  10. retinitis pigmentosa GTPase regulator interacting protein 1 (show RPGRIP1 Antibodies) and nephrocystin-4 interact strongly in vitro and in vivo, and that they colocalize in the retina

Mouse (Murine) Nephronophthisis 4 (NPHP4) interaction partners

  1. A mutation in NPHP4 in mice does not result in renal defects which are observed in human patients with mutations in NPHP4, but they do develop severe photoreceptor degeneration and extinguished rod and cone ERG (show ERG Antibodies) responses.

  2. retinitis pigmentosa GTPase regulator interacting protein 1 (show RPGRIP1 Antibodies) and nephrocystin-4 interact strongly in vitro and in vivo, and that they colocalize in the retina

  3. Recessive mutations in the NPHP4 gene, encoding the protein nephroretinin, in humans cause nephronophthisis type 4 and Senior-Loken. There is evolutionary conservation of the NPHP4 gene, with an orhtolog in C. elegans.

NPHP4 Antigen Profile

Protein Summary

This gene encodes a protein involved in renal tubular development and function. This protein interacts with nephrocystin, and belongs to a multifunctional complex that is localized to actin- and microtubule-based structures. Mutations in this gene are associated with nephronophthisis type 4, a renal disease, and with Senior-Loken syndrome type 4, a combination of nephronophthisis and retinitis pigmentosa.

Gene names and symbols associated with NPHP4

  • nephronophthisis 4 (NPHP4) antibody
  • nephronophthisis 4 (nphp4) antibody
  • nephronophthisis 4 (Nphp4) antibody
  • nephronophthisis 4 (juvenile) homolog (human) (Nphp4) antibody
  • 4930564O18Rik antibody
  • nmf192 antibody
  • NPHP4 antibody
  • POC10 antibody
  • SLSN4 antibody

Protein level used designations for NPHP4

nephronophthisis 4 , nephrocystin-4 , nephrocystin-4-like , POC10 centriolar protein homolog , nephroretinin , nephronophthisis 4 (juvenile) homolog

GENE ID SPECIES
419377 Gallus gallus
457887 Pan troglodytes
489625 Canis lupus familiaris
519551 Bos taurus
720707 Macaca mulatta
100059842 Equus caballus
100184720 Ciona intestinalis
100406722 Callithrix jacchus
100459715 Pongo abelii
100483045 Ailuropoda melanoleuca
261734 Homo sapiens
313749 Rattus norvegicus
260305 Mus musculus
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