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Nescient Helix Loop Helix 2 Proteins (NHLH2)

May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system.. Additionally we are shipping NHLH2 Antibodies (44) and NHLH2 Kits (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NHLH2 4808 Q02577
NHLH2 18072 Q64221
Rat NHLH2 NHLH2 295327  
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Top NHLH2 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag   10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$498.21
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

NHLH2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Nescient Helix Loop Helix 2 (NHLH2) Interaction Partners

Human Nescient Helix Loop Helix 2 (NHLH2) interaction partners

  1. These data support part of our hypothesis that NHLH2 or MAO-A (show MAOA Proteins) polymorphism is associated with sedentary behavior.

  2. Leptin (show LEP Proteins) signaling regulates hypothalamic expression of Nhlh2 through Stat3 (show STAT3 Proteins).

  3. Two single nucleotide polymorphisms in the human nescient helix-loop-helix 2 (NHLH2) gene reduce mRNA stability or reduce helical structure in the DNA binding domain of the protein.

  4. The present results suggest that a transcriptional complex of LMO3 (show LMO3 Proteins) and HEN2 may contribute to the genesis and malignant phenotype of neuroblastoma (show ARHGEF16 Proteins) by inhibiting HES1 which suppresses the transactivation of Mash1 (show ASCL1 Proteins).

  5. The deregulated expression of neuronal-specific LMO3 (show LMO3 Proteins) and HEN2 contributes to the genesis and progression of human neuroblastoma (show ARHGEF16 Proteins) in a lineage-specific manner.

  6. proposes the novel hypothesis that transcriptional activity by Nhlh2 (NHLH2 in humans) controls either the ability or the motivation for exercise [review]

Mouse (Murine) Nescient Helix Loop Helix 2 (NHLH2) interaction partners

  1. suggested that the expression levels of Lmo3 and/or Hen2 could determine the fate of stem cells by inhibiting Hes1 function during nervous system development and might be a trigger of aberrant neurogenesis in vivo

  2. We found that loss of Nscl-2 results in aberrant migration of gonadotropin releasing hormone neurons in Nscl-2 mutant mice causing a lineage switch of ectopically located gonadotropin releasing hormone neurons

  3. Melanocortin 4 receptor (show MC4R Proteins) is a transcriptional target of nescient helix-loop-helix-2

  4. Nhlh2 in the central control of adipocyte function

  5. Nhlh2 transcription factor has a role in controlling genes important to energy expenditure, and more specifically voluntary physical activity of animals

  6. Regulation of body weight is linked to action of neuronal Nhlh2 on prohormone convertase mRNA levels. Direct role for transcriptional control of neuropeptide processing enzymes in etiology of adult-onset obesity.

  7. N2KO mice (with targeted deletion of Nhlh2)have fewer pregnancies, abnormal estrus cycles, and release fewer oocytes as they age. N2KO females show at least a 50% reduction in hormone-stimulated sexual behavior as measured by their lordosis quotient.

  8. Data show that NSCL-1 (show NHLH1 Proteins) and -2, together with additional cofactors, directly control transcription of the necdin (show NDN Proteins) gene.

  9. We conclude that NSCL-1 (show NHLH1 Proteins)/2 maintain migration and survival of cells in the migratory stream to the cerebellum.

  10. Nhlh2 plays a role in the development and functional maintenance of the hypothalamic-pituitary-gonadal axis

Cow (Bovine) Nescient Helix Loop Helix 2 (NHLH2) interaction partners

  1. The bovine Nhlh2 gene (bNHLH2) is cloned and shown to be highly conserved among bovine breeds.

NHLH2 Protein Profile

Protein Summary

May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system.

Gene names and symbols associated with NHLH2

  • nescient helix loop helix 2 (NHLH2)
  • nescient helix loop helix 2 (nhlh2)
  • nescient helix loop helix 2 (Nhlh2)
  • 6230401I09Rik protein
  • bHLHa34 protein
  • Hen2 protein
  • NHLH2 protein
  • Nscl-2 protein
  • NSCL2 protein
  • zgc:77245 protein

Protein level used designations for NHLH2

helix-loop-helix protein 2 , NSCL1 , nescient helix loop helix 2 , HEN-2 , NSCL-2 , class A basic helix-loop-helix protein 34

GENE ID SPECIES
395578 Gallus gallus
402968 Danio rerio
469424 Pan troglodytes
4808 Homo sapiens
18072 Mus musculus
483135 Canis lupus familiaris
525699 Bos taurus
295327 Rattus norvegicus
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