Nestin Proteins (NES)

NES encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells. Additionally we are shipping Nestin Antibodies (332) and Nestin Kits (27) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NES 10763 P48681
NES 18008 Q6P5H2
NES 25491 P21263
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Top Nestin Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$11,073.30
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$560.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag,GST tag 100 μg Log in to see 15 to 18 Days
$720.00
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
HOST_Escherichia coli (E. coli) Rat S tag,His tag   100 μg Log in to see 15 to 18 Days
$733.00
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 11 to 18 Days
$928.13
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 11 to 18 Days
$763.13
Details

NES Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

More Proteins for Nestin (NES) Interaction Partners

Human Nestin (NES) interaction partners

  1. Nestin may have an important role in GIST malignancy by regulating mitochondrial dynamics and altering intracellular ROS (show ROS1 Proteins) levels. The findings provide new clues to reveal mechanisms by which nestin mediates the proliferation and invasion of GISTs.

  2. he present study reveals that nestin expression is a prognostic indicator of a poorer survival probability in NSCLC patients receiving adjuvant platinum-based chemotherapy , although its prognostic significance still requires confirmation with larger patient populations

  3. Data suggest that negative feedback mediated by GLI3 (show GLI3 Proteins) (GLI (show GLI1 Proteins)-Kruppel family member) acts to finely tune SHH (sonic hedgehog (show SHH Proteins)) signaling. During medulloblastoma (MB) formation, nerve tissue cells appear to express nestin which hyperactivates SHH (show SHH Proteins) signaling by abolishing negative feedback by GLI3 (show GLI3 Proteins). Restoration of intrinsic negative feedback by repressing nestin expression represents a promising approach to treat MB. [REVIEW]

  4. the induction of P-gp (show ABCB4 Proteins) expression is causally associated with the expression of nestin in leukemia cells

  5. SRY (sex determining region Y)-box 10 (show SOX10 Proteins) protein (SOX10 (show SOX10 Proteins)) enhances nestin protein (NES) expression via directly binding to the promoter of NES.

  6. Immunohistochemical assessment of nestin and INPP4b (show INPP4B Proteins) provides an accurate, accessible and inexpensive tool to identify basal-like breast cancer subtype in the clinically problematic setting of weak oestrogen receptor positivity

  7. Tumor expression of nestin might be a valuable prognostic factor for survival in patients with advanced ovarian cancer. With regard to its endothelial expression, nestin might be as reliable as CD34 (show CD34 Proteins) for quantifying tumor angiogenesis.

  8. Our findings provide evidence suggesting that nestin regulation is negatively controlled epigenetically by TET2 in melanoma

  9. phosphorylation of nestin at Thr315 and/or Thr1299 affects cell proliferation, and inhibition of both phosphorylation sites suppresses invasion and metastasis of human pancreatic cancer. Inhibiting nestin phosphorylation at these two sites may represent a novel therapeutic strategy for pancreatic cancer.

  10. Nestin and CD146 (show MCAM Proteins) are expressed in breast cancer cells with highly aggressive potency. They might contribute to disease relapse in breast cancer by activating the epithelial-mesenchymal transition pathway and assist tumor neovascularization.

Mouse (Murine) Nestin (NES) interaction partners

  1. demonstrate that following postnatal ablation of granule cell progenitors, Nestin-expressing progenitors, specified during mid-embryogenesis to produce astroglia and interneurons, switch their fate and generate granule neurons in mice.

  2. The nestin(+) cells contribute to all subsets of the complex stromal populations that can be found in lymph nodes.

  3. nestin may label progenitor cells during inner ear development and may not be a stem cell marker in the mature organ of Corti

  4. Nestin(+) cells are one important type of progenitor cell in bone marrow and are associated with bone remodeling. These data indicate that DMP1 (show DMP1 Proteins) plays negative roles in differentiation of Nestin(+) cells and bone formation.

  5. Our findings show how Nestin drives hedgehog (show SHH Proteins) pathway-driven cancers and the tumor-promoting effects of Nestin were mediated by binding to Gli3 (show GLI3 Proteins), a zinc finger transcription factor (show OSR1 Proteins) that negatively regulates hedgehog (show SHH Proteins) signaling.

  6. Based on a nestin-green fluorescent protein (NGFP) transgenic model, a histological inventory has been performed to deliver an overview of neuronal and glial markers for the various parts of the gastrointestinal tract in newborn (postnatal day 7) and adult mice under homeostatic conditions.

  7. EGFR (show EGFR Proteins) and Nestin showed to have vital role during mice development, and considered to be suitable markers for the study of skin stem cells.

  8. Nestin was shown to affect cell number and was significantly enhanced in lungs early during development of pulmonary hypertension.

  9. Chromatin Remodeling Factor (show ASH1L Proteins) Brg1 (show SMARCA4 Proteins) Supports the Early Maintenance and Late Responsiveness of Nestin-Lineage Adult Neural Stem and Progenitor Cells.

  10. Our results proposed nestin+ bone marrow derived cells as mobilized candidates in skin injury repair

Zebrafish Nestin (NES) interaction partners

  1. Nestin gene may serve as a marker for stem cells and proliferating precursors in the developing embryonic nervous system as well as in the postembryonic brain[Nestin]

  2. Results suggest that nestin is essential for brain and eye development probably through control of progenitor cell apoptosis.

  3. Cells expressing the two reporters display radial glial morphology, colocalize with the NSC marker Sox2 (show SOX2 Proteins), undergo proliferation, and are capable of self-renewal within the matrix of distinct thickness in the telencephalon.

Nestin (NES) Protein Profile

Protein Summary

This gene encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells.

Gene names and symbols associated with Nestin Proteins (NES)

  • nestin (NES)
  • nestin (nes)
  • nestin (Nes)
  • AA166324 protein
  • C78523 protein
  • ESTM46 protein
  • NES protein
  • paranemin protein

Protein level used designations for Nestin Proteins (NES)

transitin , tanabin , nestin , nestin-like , intermediate filament protein

GENE ID SPECIES
742303 Pan troglodytes
395890 Gallus gallus
397776 Xenopus laevis
100064419 Equus caballus
100409695 Callithrix jacchus
100456772 Pongo abelii
100472137 Ailuropoda melanoleuca
100584337 Nomascus leucogenys
10763 Homo sapiens
18008 Mus musculus
25491 Rattus norvegicus
490410 Canis lupus familiaris
522383 Bos taurus
100008641 Oryctolagus cuniculus
100150939 Danio rerio
101843961 Mesocricetus auratus
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