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Netrin is included in a family of laminin-related secreted proteins. Additionally we are shipping Netrin 1 Antibodies (81) and Netrin 1 Kits (51) and many more products for this protein.
Showing 10 out of 13 products:
Human Netrin 1 Protein expressed in Human - ABIN1344382
Ozmadenci, Féraud, Markossian, Kress, Ducarouge, Gibert, Ge, Durand, Gadot, Plateroti, Bennaceur-Griscelli, Scoazec, Gil, Deng, Bernet, Mehlen, Lavial: Netrin-1 regulates somatic cell reprogramming and pluripotency maintenance. in Nature communications 2015
our data suggest that netrin-1 contributes to the migration of the neural folds towards the midline
Partial knock down of netrin-1 confirms that this chemoattractive ligand of neogenin (show NEO1 Proteins) acts in the same early forming dorsoventral brain pathway.
Studies identify netrin-1 as an active participant in retinal ganglion cell axon presynaptic differentiation, not only as they navigate along their pathway but also at their target.
Akt (show AKT1 Proteins)-FoxO1 (show FOXO1 Proteins) signaling pathway plays an essential role during liver regeneration
MUC4 (show MUC4 Proteins) has a role in promoting neural invasion mediated by the axon guidance factor Netrin-1 in pancreatic ductal adenocarcinoma
Netrin-1 enhanced infectivity of hepatitis C virus particles and promoted viral entry by increasing the activation and decreasing the recycling of the epidermal growth factor receptor (EGFR (show EGFR Proteins)), a protein that is dysregulated in hepatocellular carcinoma.
identify the V-2 domain of netrin-1 to be important for its interaction with the Ig1/Ig2 domains of UNC5H2 (show UNC5B Proteins)
NTN1-DCC (show DCC Proteins) pathway contains targets of FDA-approved drugs and may offer promise for guiding applied clinical research on preventive and therapeutic interventions for AMD (show AMD1 Proteins)
These results identify Netrin-1 as a key regulator of osteoclast differentiation that may be a new target for bone therapies.
Investigation of the mechanisms that trigger local translation revealed a role for calcium-dependent retrograde netrin-1/DCC (show DCC Proteins) receptor signaling.
Netrin-1 stimulates phosphatase 1A to dephosphorylate YAP (show YAP1 Proteins), which leads to decreased ubiquitination and degradation, enhancing YAP (show YAP1 Proteins) accumulation and signaling
results demonstrate that netrin 1 is an important regulator of blood-brain barrier maintenance that protects the central nervous system against inflammatory conditions such as multiple sclerosis.
Increased maternal netrin-4 (show NTN4 Proteins) levels in IUGR neonates may reflect in utero hypoxia, while the negative correlations between fetal netrin-1 and -4 levels may exert the dynamic balance between their angio- and anti-angiogenic properties.
The results of this study showed that NTN1 contributes to the formation of the Corpus callosum by promoting the preceding removal of the midline leptomeningeal cells and interhemispheric fusion.
netrin-1 loss-of-function causes embryonic lethality.
Results show that the Netrin-1-induced axon slowdown is mediated by complex Ca2 (show CA2 Proteins)+ dynamics and involves Ca2 (show CA2 Proteins)+ efflux from the ER via the Ryanodine channels
Netrin-1 haploinsufficiency leads to increased dopamine content in the medial prefrontal cortex.
FLRT3 (show FLRT3 Proteins) is a modulator of Netrin-1 response in developing axons.
Low levels of Ntn1 can account for persistent attraction to the midline in hypomorphs. By contrast, Ntn1 null mice do not show all of the phenotypes reported for Unc5 receptor (show UNC5B Proteins) mutants, indicating that Ntn1 is not necessarily the dominant ligand for Unc5 family members in vivo and ruling out primary roles in survival or angiogenesis.
Integration of shallow gradients of Shh (show SHH Proteins) and Netrin-1 synergistically guides commissural axons in the growing spinal cord.
Results suggest that down syndrome cell adhesion molecule (show DSCAM Proteins) collaborates with deleted in colorectal cancer (show DCC Proteins) to regulate microtubule dynamics via direct binding to dynamic TUBB3 (show TUBB3 Proteins) in Netrin-1-induced axon branching.
Treatment with endogenous anti-inflammatory protein netrin-1 reduces pulmonary inflammation during the initial stages of acute lung injury.
Netrin-1 could be important for follicular function in the swine.
findings show that the netrin-1 and p53RDL1 (show UNC5B Proteins) system may regulate the induction of apoptosis in porcine granulosa cells
Netrin is included in a family of laminin-related secreted proteins. The function of this gene has not yet been defined\; however, netrin is thought to be involved in axon guidance and cell migration during development. Mutations and loss of expression of netrin suggest that variation in netrin may be involved in cancer development.
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, netrin 1, mouse, homolog of