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Netrin is included in a family of laminin-related secreted proteins. Additionally we are shipping Netrin 1 Antibodies (104) and Netrin 1 Kits (43) and many more products for this protein.
Showing 10 out of 13 products:
Human Netrin 1 Protein expressed in Human - ABIN1344382
Ozmadenci, Féraud, Markossian, Kress, Ducarouge, Gibert, Ge, Durand, Gadot, Plateroti, Bennaceur-Griscelli, Scoazec, Gil, Deng, Bernet, Mehlen, Lavial: Netrin-1 regulates somatic cell reprogramming and pluripotency maintenance. in Nature communications 2015
our data suggest that netrin-1 contributes to the migration of the neural folds towards the midline
Partial knock down of netrin-1 confirms that this chemoattractive ligand of neogenin (show NEO1 Proteins) acts in the same early forming dorsoventral brain pathway.
Studies identify netrin-1 as an active participant in retinal ganglion cell axon presynaptic differentiation, not only as they navigate along their pathway but also at their target.
Netrin-1 reduced the Abeta1- 40-induced Abeta1-42 increase, increased sAbetaPPalpha, and reversed the Abeta (show APP Proteins)-induced sAbetaPPalpha decrease in vitro
Akt (show AKT1 Proteins)-FoxO1 (show FOXO1 Proteins) signaling pathway plays an essential role during liver regeneration
MUC4 (show MUC4 Proteins) has a role in promoting neural invasion mediated by the axon guidance factor Netrin-1 in pancreatic ductal adenocarcinoma
Netrin-1 enhanced infectivity of hepatitis C virus particles and promoted viral entry by increasing the activation and decreasing the recycling of the epidermal growth factor receptor (EGFR (show EGFR Proteins)), a protein that is dysregulated in hepatocellular carcinoma.
identify the V-2 domain of netrin-1 to be important for its interaction with the Ig1/Ig2 domains of UNC5H2 (show UNC5B Proteins)
NTN1-DCC (show DCC Proteins) pathway contains targets of FDA-approved drugs and may offer promise for guiding applied clinical research on preventive and therapeutic interventions for AMD (show AMD1 Proteins)
These results identify Netrin-1 as a key regulator of osteoclast differentiation that may be a new target for bone therapies.
Investigation of the mechanisms that trigger local translation revealed a role for calcium-dependent retrograde netrin-1/DCC (show DCC Proteins) receptor signaling.
Netrin-1 stimulates phosphatase 1A to dephosphorylate YAP (show YAP1 Proteins), which leads to decreased ubiquitination and degradation, enhancing YAP (show YAP1 Proteins) accumulation and signaling
results demonstrate that netrin 1 is an important regulator of blood-brain barrier maintenance that protects the central nervous system against inflammatory conditions such as multiple sclerosis.
Netrin-1 reduced the Abeta1- 40-induced Abeta1-42 increase, increased sAbetaPPalpha, and reversed the Abeta (show APP Proteins)-induced sAbetaPPalpha decrease in vitro; in vivo, induction of netrin-1 expression in PDAbetaPPSwe/Ind transgenic mice resulted in reductions in both Abeta1-42 and Abeta1- 40, and ICV delivery of netrin-1 to PDAbetaPPSwe/Ind mice increased sAbetaPPalpha, decreased Abeta (show APP Proteins), and improved working memory.
The Netrin-1 and ephrin-B2 (show EFNB2 Proteins) synergistic growth cone responses involve the potentiation of Src (show SRC Proteins) family kinase signaling, a common effector of both pathways.
netrin1 prevented cardiac hypertrophy and heart failure through the negative regulation of the MEKK1 (show MAP2K1 Proteins)-dependent MEKERK1/2 and JNK1 (show MAPK8 Proteins)/2 signaling pathways.
The results of this study showed that NTN1 contributes to the formation of the Corpus callosum by promoting the preceding removal of the midline leptomeningeal cells and interhemispheric fusion.
netrin-1 loss-of-function causes embryonic lethality.
Results show that the Netrin-1-induced axon slowdown is mediated by complex Ca2 (show CA2 Proteins)+ dynamics and involves Ca2 (show CA2 Proteins)+ efflux from the ER via the Ryanodine channels
Netrin-1 haploinsufficiency leads to increased dopamine content in the medial prefrontal cortex.
FLRT3 (show FLRT3 Proteins) is a modulator of Netrin-1 response in developing axons.
Treatment with endogenous anti-inflammatory protein netrin-1 reduces pulmonary inflammation during the initial stages of acute lung injury.
Netrin-1 could be important for follicular function in the swine.
findings show that the netrin-1 and p53RDL1 (show UNC5B Proteins) system may regulate the induction of apoptosis in porcine granulosa cells
Netrin is included in a family of laminin-related secreted proteins. The function of this gene has not yet been defined\; however, netrin is thought to be involved in axon guidance and cell migration during development. Mutations and loss of expression of netrin suggest that variation in netrin may be involved in cancer development.
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, netrin 1, mouse, homolog of