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Netrin G1 (NTNG1) belongs to a conserved family of proteins that act as axon guidance cues during vertebrate nervous system development (Nakashiba et al., 2000 [PubMed 10964959]).[supplied by OMIM, Mar 2008].. Additionally we are shipping Netrin G1 Antibodies (38) and Netrin G1 Proteins (6) and many more products for this protein.
examined the hypothesis that NTNG1 allelic variation contributes to the risk for schizophrenia
Interaction between the tripartite NGL-1 (show LRRC4C ELISA Kits), netrin-G1 and LAR (show PTPRF ELISA Kits) adhesion complex promotes development of excitatory synapses.
Our finding nominates the minor G allele of the NTNG1 rs628117 single nucleotide polymorphism as a risk factor for ischemic stroke at least in Armenian population.
Genotype and allele frequencies of single nucleotide polymorphisms on NTNG1 are significantly associated with schizophrenia.
Netrin-G1 is an important part of the NGL-1 (show LRRC4C ELISA Kits) receptor and functions to promote the outgrowth of dorsal thalamic axons.
findings suggest that netrin G1 or a nearby gene may contribute to overall genetic risk for schizophrenia
Specific haplotypes encompassing alternatively spliced exons of NTNG1 were associated with schizophrenia, and concordantly, messenger ribonucleic acid isoform expression was significantly different between schizophrenic and control brains.
Sequence analysis of the cloned junction fragment indicated that on chromosome 1 the predominantly brain-expressed Netrin G1 (NTNG1) gene is disrupted, whereas on chromosome 7 there was no indication for a truncated gene
NTNG1 may use alternative splicing to diversify its function in a developmentally and tissue-specific manner.
Mutations in the NTNG1 gene appear to be a rare cause of Rett syndrome but NTNG1 function demands further investigation in relation to the central nervous system pathophysiology of the disorder.
Pre-synaptic netrin-G1 and netrin-G2 diversify the complexity of vertebrate behaviors and differentially regulate post-synaptic properties.
netrin-G/NGL (show ERBB2 ELISA Kits) interactions differentially control synaptic plasticity in distinct circuits via retrograde signaling mechanisms
The complementary expression patterns of Ntng1 and Ntng2 are determined by transcriptional cis (show CISH ELISA Kits)-regulatory elements widely scattered in these loci.
Netrin G1 (NTNG1) belongs to a conserved family of proteins that act as axon guidance cues during vertebrate nervous system development (Nakashiba et al., 2000
, netrin G2
, axon guidance molecule
, laminet 1
, netrin G1f