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anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) Antibodies

displays differential expression after induction by nerve growth factor [RGD, Feb 2006].. Additionally we are shipping NEDD8 Proteins (28) and NEDD8 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NEDD8 4738 Q15843
NEDD8 25490 Q71UE8
NEDD8 18002 P29595
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Top anti-NEDD8 Antibodies at antibodies-online.com

Showing 10 out of 106 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of NEDD8 polyclonal antibody (ABIN388037) in HeLa cell lysate. NEDD8 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated EIA, FACS, IF, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$423.50
Details
Human Mouse Un-conjugated ICC, FACS, IHC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Flow cytometric analysis of Hela cells using NEDD8 mouse mAb (green) and negative control (red) . 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Anti-NEDD8 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959353 dilution 1:100. 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from Jurkat cells, using NEDD8 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using NEDD8 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Western blot analysis of extracts from Jurkat cells, using NEDD8 Antibody. The lane on the right is treated with the synthesized peptide. 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Mouse Un-conjugated ICC, FACS, IF, IHC, ELISA, WB 100 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$676.50
Details

NEDD8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-NEDD8 Antibodies

  1. Human Polyclonal NEDD8 Primary Antibody for IHC (p), WB - ABIN388037 : Wu, Yamoah, Dolios, Gan-Erdene, Tan, Chen, Lee, Wei, Wilkinson, Wang, Pan: DEN1 is a dual function protease capable of processing the C terminus of Nedd8 and deconjugating hyper-neddylated CUL1. in The Journal of biological chemistry 2003 (PubMed)
    Show all 5 references for ABIN388037

  2. Human Polyclonal NEDD8 Primary Antibody for EIA, IHC (p) - ABIN356744 : Bohnsack, Haas: Conservation in the mechanism of Nedd8 activation by the human AppBp1-Uba3 heterodimer. in The Journal of biological chemistry 2003 (PubMed)
    Show all 3 references for ABIN356744

  3. Human Monoclonal NEDD8 Primary Antibody for EIA, FACS - ABIN1108403 : Sowa, Bennett, Gygi, Harper: Defining the human deubiquitinating enzyme interaction landscape. in Cell 2009 (PubMed)
    Show all 2 references for ABIN1108403

  4. Human Monoclonal NEDD8 Primary Antibody for ICC, FACS - ABIN969546 : Ohki, Funatsu, Konishi, Chiba: The mechanism of poly-NEDD8 chain formation in vitro. in Biochemical and biophysical research communications 2009 (PubMed)

More Antibodies against NEDD8 Interaction Partners

Fruit Fly (Drosophila melanogaster) Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) interaction partners

  1. the Cul1 (show CUL1 Antibodies)-based SCF (show KITLG Antibodies) complex requires Nedd8 modification for the degradation processes of Ci, Arm, and CycE (show CCNE1 Antibodies) in vivo

  2. Genetic analyses indicate that a balance between neddylation and deneddylation maintained by DEN1 (show SENP8 Antibodies) is crucial for animal viability.

Human Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) interaction partners

  1. Nedd8(Q40E) cannot induce the same structural effect on Cul1 (show CUL1 Antibodies)-Rbx1 as wild-type Nedd8.

  2. findings add novel evidence showing, for what we believe the first time, that NEDD8-mediated neddylation is required for normal human endometrial functions

  3. In endothelial dysfunction, HDAC2 (show HDAC2 Antibodies) levels were reciprocally regulated by ectopic expression of NEDD8 and the de-NEDDylating enzyme SENP8 (show SENP8 Antibodies).

  4. we report that MLN4924 (NEDD8 enzyme inhibitor ) specifically inhibited protein neddylation, inactivated cullin-RING E3 ligase (CRL (show IL31RA Antibodies)), the best-known neddylation substrate, and induced the accumulation CRL (show IL31RA Antibodies) substrates in lymphoma cells.

  5. E1 (NAE1 (show NAE1 Antibodies) and UBA3 (show UBA3 Antibodies)) and E2 (UBC12 (show ube2m Antibodies)) enzymes, as well as global NEDD8 conjugation, were upregulated in over 2/3 of human intrahepatic cholangiocarcinoma

  6. This work sheds new light on the roles of NEDD8 lysines on neddylation cascades and provides a dominant negative mutant for the study of neddylation and its biological functions.

  7. a role of Nedd8 in regulating caspase-1 (show CASP1 Antibodies) activation following inflammasome activation

  8. NEDD8 negatively regulates the DNA damage repair process through suppression of the ubiquitylation of H2A and gammaH2AX, which further blocks the recruitment of the damage response protein BRCA1.

  9. SCCRO3 functions as a tumor suppressor by antagonizing the neddylation activity of SCCRO (show DCUN1D1 Antibodies)

  10. Study reports the structure of a trapped RING E3-E2 approximately UBL-target intermediate representing RBX1-UBC12 approximately NEDD8-CUL1-DCN1, which reveals the mechanism of NEDD8 ligation and how a particular UBL and acceptor lysine are matched by a multifunctional RING E3.

Mouse (Murine) Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) interaction partners

  1. a role of Nedd8 in regulating caspase-1 (show CASP1 Antibodies) activation following inflammasome activation

  2. Nedd8 and its associated E2 carrier protein (Ubc12 (show ube2m Antibodies)) and E3-SCF (show KITLG Antibodies) ligase play a key role in regulating the expression and activity of ENaC (show SCNN1A Antibodies) in alveolar pneumocytes.

  3. a new regulatory mechanism of RCAN1 (show RCAN1 Antibodies) function

  4. c-Cbl conjugates neural precursor cell-expressed, developmentally downregulated 8 (NEDD8), a ubiquitin-like protein, to TbetaRII at Lys556 and Lys567.

  5. The NEDD8 pathway appears to play an important role in CD4 (show CD4 Antibodies)+ T-cell-mediated inflammatory responses

  6. Nedd8 and AhR (show AHR Antibodies) localize to overlapping areas in the heart and spinal ganglia, raising the possibility that this interaction may play a role in organogenesis

  7. NEDD8 and ubiquitin function in a redundant manner in controlling receptor endocytic pathways.

  8. SCCRO recruits Ubc12 approximately NEDD8 to the CAND1-Cul1-ROC1 complex but that this is not sufficient to dissociate or overcome the inhibitory effects of CAND1 on cullin neddylation

NEDD8 Antigen Profile

Protein Summary

displays differential expression after induction by nerve growth factor

Gene names and symbols associated with NEDD8

  • CG10679 gene product from transcript CG10679-RA (Nedd8) antibody
  • neural precursor cell expressed, developmentally down-regulated 8 (nedd8) antibody
  • neural precursor cell expressed, developmentally down-regulated 8 (NEDD8) antibody
  • Nedd8 (Nedd8) antibody
  • ubiquitin-like protein Nedd8 (nedd8) antibody
  • NEDD8 protein (nedd8) antibody
  • NEDD8-like (LOC100520086) antibody
  • neural precursor cell expressed, developmentally down-regulated 8 (Nedd8) antibody
  • neural precursor cell expressed, developmentally down-regulated gene 8 (Nedd8) antibody
  • CG10679 antibody
  • DDBDRAFT_0218116 antibody
  • DDBDRAFT_0238041 antibody
  • DDB_0218116 antibody
  • DDB_0238041 antibody
  • Dmel\\CG10679 antibody
  • dNEDD8 antibody
  • GB17785 antibody
  • NEDD-8 antibody
  • nedd8 antibody
  • Rub1 antibody
  • si:zc14a17.5 antibody
  • ubiquitin antibody

Protein level used designations for NEDD8

CG10679-PA , Nedd8-PA , neural precursor cell-expressed developmentally downregulated , neural precursor cell expressed, developmentally down-regulated 8 , Nedd8 , NEDD8 protein , neddylin , ubiquitin-like protein Nedd8 , NEDD8 , neural precursor cell expressed, developmentally down-regulated gene 8 , NEDD-8 , neural precursor cell expressed developmentally down-regulated protein 8

GENE ID SPECIES
35151 Drosophila melanogaster
368667 Danio rerio
480265 Canis lupus familiaris
549727 Xenopus (Silurana) tropicalis
552822 Apis mellifera
704026 Macaca mulatta
715763 Macaca mulatta
8621655 Dictyostelium discoideum AX4
100301786 Oncorhynchus mykiss
100528101 Ictalurus punctatus
100520086 Sus scrofa
4738 Homo sapiens
25490 Rattus norvegicus
286796 Bos taurus
100009008 Oryctolagus cuniculus
18002 Mus musculus
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