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Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 Proteins (NEDD8)

displays differential expression after induction by nerve growth factor [RGD, Feb 2006].. Additionally we are shipping NEDD8 Antibodies (102) and NEDD8 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NEDD8 4738 Q15843
NEDD8 25490 Q71UE8
NEDD8 18002 P29595
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Top NEDD8 Proteins at antibodies-online.com

Showing 10 out of 28 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,101.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,101.00
Details
Yeast Rabbit His tag   1 mg Log in to see 56 to 66 Days
$2,101.00
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 5 Days
$88.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$364.64
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   25 μg Log in to see 2 to 3 Days
$273.00
Details

NEDD8 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
, , , , , ,
Rat (Rattus)

Mouse (Murine)

Top referenced NEDD8 Proteins

  1. Human NEDD8 Protein expressed in Escherichia coli (E. coli) - ABIN666733 : Hori, Osaka, Chiba, Miyamoto, Okabayashi, Shimbara, Kato, Tanaka: Covalent modification of all members of human cullin family proteins by NEDD8. in Oncogene 2000 (PubMed)
    Show all 2 references for ABIN666733

More Proteins for Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) Interaction Partners

Fruit Fly (Drosophila melanogaster) Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) interaction partners

  1. the Cul1 (show CUL1 Proteins)-based SCF (show KITLG Proteins) complex requires Nedd8 modification for the degradation processes of Ci, Arm, and CycE (show CCNE1 Proteins) in vivo

  2. Genetic analyses indicate that a balance between neddylation and deneddylation maintained by DEN1 (show SENP8 Proteins) is crucial for animal viability.

Human Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) interaction partners

  1. Nedd8(Q40E) cannot induce the same structural effect on Cul1 (show CUL1 Proteins)-Rbx1 as wild-type Nedd8.

  2. findings add novel evidence showing, for what we believe the first time, that NEDD8-mediated neddylation is required for normal human endometrial functions

  3. In endothelial dysfunction, HDAC2 (show HDAC2 Proteins) levels were reciprocally regulated by ectopic expression of NEDD8 and the de-NEDDylating enzyme SENP8 (show SENP8 Proteins).

  4. we report that MLN4924 (NEDD8 enzyme inhibitor ) specifically inhibited protein neddylation, inactivated cullin-RING E3 ligase (CRL), the best-known neddylation substrate, and induced the accumulation CRL substrates in lymphoma cells.

  5. E1 (NAE1 (show NAE1 Proteins) and UBA3 (show UBA3 Proteins)) and E2 (UBC12 (show ube2m Proteins)) enzymes, as well as global NEDD8 conjugation, were upregulated in over 2/3 of human intrahepatic cholangiocarcinoma

  6. This work sheds new light on the roles of NEDD8 lysines on neddylation cascades and provides a dominant negative mutant for the study of neddylation and its biological functions.

  7. a role of Nedd8 in regulating caspase-1 (show CASP1 Proteins) activation following inflammasome activation

  8. NEDD8 negatively regulates the DNA damage repair process through suppression of the ubiquitylation of H2A and gammaH2AX, which further blocks the recruitment of the damage response protein BRCA1.

  9. SCCRO3 functions as a tumor suppressor by antagonizing the neddylation activity of SCCRO (show DCUN1D1 Proteins)

  10. Study reports the structure of a trapped RING E3-E2 approximately UBL-target intermediate representing RBX1-UBC12 approximately NEDD8-CUL1-DCN1, which reveals the mechanism of NEDD8 ligation and how a particular UBL and acceptor lysine are matched by a multifunctional RING E3.

Mouse (Murine) Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) interaction partners

  1. a role of Nedd8 in regulating caspase-1 (show CASP1 Proteins) activation following inflammasome activation

  2. Nedd8 and its associated E2 carrier protein (Ubc12 (show ube2m Proteins)) and E3-SCF (show KITLG Proteins) ligase play a key role in regulating the expression and activity of ENaC (show SCNN1A Proteins) in alveolar pneumocytes.

  3. a new regulatory mechanism of RCAN1 (show RCAN1 Proteins) function

  4. c-Cbl conjugates neural precursor cell-expressed, developmentally downregulated 8 (NEDD8), a ubiquitin-like protein, to TbetaRII at Lys556 and Lys567.

  5. The NEDD8 pathway appears to play an important role in CD4 (show CD4 Proteins)+ T-cell-mediated inflammatory responses

  6. Nedd8 and AhR (show AHR Proteins) localize to overlapping areas in the heart and spinal ganglia, raising the possibility that this interaction may play a role in organogenesis

  7. NEDD8 and ubiquitin function in a redundant manner in controlling receptor endocytic pathways.

  8. SCCRO recruits Ubc12 approximately NEDD8 to the CAND1-Cul1-ROC1 complex but that this is not sufficient to dissociate or overcome the inhibitory effects of CAND1 on cullin neddylation

NEDD8 Protein Profile

Protein Summary

displays differential expression after induction by nerve growth factor

Gene names and symbols associated with NEDD8

  • CG10679 gene product from transcript CG10679-RA (Nedd8)
  • neural precursor cell expressed, developmentally down-regulated 8 (nedd8)
  • neural precursor cell expressed, developmentally down-regulated 8 (NEDD8)
  • Nedd8 (Nedd8)
  • ubiquitin-like protein Nedd8 (nedd8)
  • NEDD8 protein (nedd8)
  • NEDD8-like (LOC100520086)
  • neural precursor cell expressed, developmentally down-regulated 8 (Nedd8)
  • neural precursor cell expressed, developmentally down-regulated gene 8 (Nedd8)
  • CG10679 protein
  • DDBDRAFT_0218116 protein
  • DDBDRAFT_0238041 protein
  • DDB_0218116 protein
  • DDB_0238041 protein
  • Dmel\\CG10679 protein
  • dNEDD8 protein
  • GB17785 protein
  • NEDD-8 protein
  • nedd8 protein
  • Rub1 protein
  • si:zc14a17.5 protein
  • ubiquitin protein

Protein level used designations for NEDD8

CG10679-PA , Nedd8-PA , neural precursor cell-expressed developmentally downregulated , neural precursor cell expressed, developmentally down-regulated 8 , Nedd8 , NEDD8 protein , neddylin , ubiquitin-like protein Nedd8 , NEDD8 , neural precursor cell expressed, developmentally down-regulated gene 8 , NEDD-8 , neural precursor cell expressed developmentally down-regulated protein 8

GENE ID SPECIES
35151 Drosophila melanogaster
368667 Danio rerio
480265 Canis lupus familiaris
549727 Xenopus (Silurana) tropicalis
552822 Apis mellifera
704026 Macaca mulatta
715763 Macaca mulatta
8621655 Dictyostelium discoideum AX4
100301786 Oncorhynchus mykiss
100528101 Ictalurus punctatus
100520086 Sus scrofa
4738 Homo sapiens
25490 Rattus norvegicus
286796 Bos taurus
100009008 Oryctolagus cuniculus
18002 Mus musculus
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