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anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9) Antibodies

The protein encoded by NEDD9 is a member of the CRK-associated substrates family. Additionally we are shipping NEDD9 Proteins (6) and NEDD9 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NEDD9 4739 Q14511
NEDD9 291044  
NEDD9 18003 O35177
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Top anti-NEDD9 Antibodies at antibodies-online.com

Showing 10 out of 65 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-NEDD9 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: 293T cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, WB WB Suggested Anti-NEDD9 Antibody Titration: 5.0ug/mlPositive Control: 721_B cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IHC (p), WB NEDD9 Antibody (Center) (ABIN658513) western blot analysis in MCF-7 cell line lysates (35 µg/lane). This demonstrates the NEDD9 antibody detected the NEDD9 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Dog Goat Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Mouse Mouse Un-conjugated ICC, FACS, IHC (fro), IF, IP, WB Immunofluorescence staining of 4% PFA fixed MCF-7 cells showing focal adhesion localization of HEF-1 protein 50 μL Log in to see 5 to 6 Days
$402.29
Details
Human Goat Un-conjugated ELISA, WB ABIN334443 (0.1µg/ml) staining of Human Kidney lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Mouse Un-conjugated ICC, IF, IP   50 μL Log in to see 5 to 6 Days
$402.29
Details
Human Mouse Un-conjugated IF, ELISA, WB Immunofluorescence of monoclonal antibody to NEDD9 on HeLa cell. [antibody concentration 10 ug/ml] Western Blot analysis of NEDD9 expression in transfected 293T cell line by NEDD9 monoclonal antibody (M01), clone 1B4.Lane 1: NEDD9 transfected lysate(92.9 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: BCL-1 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details

NEDD9 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Rat (Rattus)
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Mouse (Murine)
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Top referenced anti-NEDD9 Antibodies

  1. Mouse (Murine) Monoclonal NEDD9 Primary Antibody for ICC, FACS - ABIN108572 : ONeill, Golemis: Proteolysis of the docking protein HEF1 and implications for focal adhesion dynamics. in Molecular and cellular biology 2001 (PubMed)
    Show all 3 references for ABIN108572

  2. Human Polyclonal NEDD9 Primary Antibody for IHC (p), WB - ABIN658513 : Corneveaux, Myers, Allen, Pruzin, Ramirez, Engel, Nalls, Chen, Lee, Chewning, Villa, Meechoovet, Gerber, Frost, Benson, OReilly, Chibnik, Shulman, Singleton, Craig, Van Keuren-Jensen, Dunckley, Bennett, De Jager, Heward, Hardy, Reiman, Huentelman: Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals. in Human molecular genetics 2010 (PubMed)
    Show all 2 references for ABIN658513

  3. Human Monoclonal NEDD9 Primary Antibody for IF, ELISA - ABIN561951 : Li, Grupe, Rowland, Holmans, Segurado, Abraham, Jones, Catanese, Ross, Mayo, Martinez, Hollingworth, Goate, Cairns, Racette, Perlmutter, ODonovan, Morris, Brayne, Rubinsztein, Lovestone, Thal, Owen et al.: Evidence that common variation in NEDD9 is associated with susceptibility to late-onset Alzheimer's and Parkinson's disease. ... in Human molecular genetics 2008 (PubMed)

  4. Human Polyclonal NEDD9 Primary Antibody for ELISA, WB - ABIN334443 : Kim, Gans, Nogueira, Wang, Paik, Feng, Brennan, Hahn, Cordon-Cardo, Wagner, Flotte, Duncan, Granter, Chin: Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene. in Cell 2006 (PubMed)

More Antibodies against NEDD9 Interaction Partners

Human Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9) interaction partners

  1. NEDD9 has an essential role in development as well as in neoplastic cell proliferation, apoptosis, adhesion, migration and invasion. (Review)

  2. The presence of the dna fragment in the NSCLC-N6-L16 (show MRPL16 Antibodies) cell ChIP assays demonstrated a physical link between NEDD9 and p53 (show TP53 Antibodies).

  3. siRNA suppression of NEDD9 inhibits proliferation and enhances apoptosis in renal cell carcinoma (show MOK Antibodies).

  4. Serum NEDD9 was elevated in gastric cancer patients and had an unfavorable prognostic effect.

  5. BCAR3 (show BCAR3 Antibodies) is an essential interactor and mediator of HEF1-induced migration.

  6. Study uncovers a new role of NEDD9 as a regulator of integrin trafficking through CAV1 (show CAV1 Antibodies)-dependent endocytosis, and provide new insight into the regulation of migration of breast cancer cells.

  7. miR145 is inversely correlated with NEDD9 expression in pancreatic cancer tissues and restoration of miR145 in Panc1 cells reduced NEDD9 mRNA and protein expression accompanied by inhibition of cell proliferation, invasion and migration.

  8. Results establish a novel role for NEDD9 as a key regulator of Arf6 (show ARF6 Antibodies)-dependent trafficking of MMP14 (show MMP14 Antibodies) and its invasive properties, highlighting the basic mechanism utilized by NEDD9 to support breast cancer cell invasion and metastasis.

  9. discuss emerging evidence supporting involvement of NEDD9 in additional pathological conditions, including stroke and polycystic kidney disease

  10. our findings suggest that NEDD9 acts as an oncogene (show RAB1A Antibodies) and promotes GC metastasis via EMT (show ITK Antibodies).

Mouse (Murine) Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9) interaction partners

  1. NEDD9 is required for the maintenance of dendritic spines in the hippocampus.

  2. NEDD9 has an essential role in development as well as in neoplastic cell proliferation, apoptosis, adhesion, migration and invasion. (Review)

  3. Thus the RARE upstream of the Nedd9 2B promoter is necessary for much of the endogenous gene expression during early development as well as ectopic expression in response to atRA.

  4. suggest that Cas-L/NEDD9 plays a pivotal role in the pathophysiology of CIA (show NCOA5 Antibodies), and that Cas-L/NEDD9 may be a potential molecular target for the treatment of RA

  5. Data indicate that Src kinase (show CSK Antibodies) modulates the transit time of NEDD9 (neural precursor cell expressed developmentally down-regulated gene 9) at focal adhesion sites.

  6. These results indicated an important modifier action of Nedd9 on autosomal dominant polycystic kidney disease pathogenesis involving failure to activate Aurora-A (show AURKA Antibodies).

  7. these results indicate a functional requirement for NEDD9 in the growth of mammary cancer progenitor cells

  8. Tyrosine Y189 in the substrate domain of the adhesion docking protein NEDD9 is conserved with p130Cas (show BCAR1 Antibodies) Y253 and regulates NEDD9-mediated migration and focal adhesion dynamics.

  9. Collectively our data suggest that NEDD9 may promote 3D cell migration by slowing focal adhesion disassembly, promoting integrin receptor activation and increasing adhesion force

  10. Myosin IIA inhibition also significantly reduces phosphorylation of the mechanosensing protein CasL (Crk-associated substrate (show BCAR1 Antibodies) the lymphocyte type), raising the possibility of a direct mechanical mechanism of signal modulation involving CasL.

NEDD9 Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with NEDD9

  • neural precursor cell expressed, developmentally down-regulated 9 (NEDD9) antibody
  • neural precursor cell expressed, developmentally down-regulated 9 (LOC100229910) antibody
  • neural precursor cell expressed, developmentally down-regulated 9 (Nedd9) antibody
  • neural precursor cell expressed, developmentally down-regulated gene 9 (Nedd9) antibody
  • Cas-L antibody
  • CAS2 antibody
  • CasL antibody
  • CASS2 antibody
  • E230025G09Rik antibody
  • HEF1 antibody
  • NEDD9 antibody

Protein level used designations for NEDD9

neural precursor cell expressed, developmentally down-regulated 9 , enhancer of filamentation 1 homolog , Cas scaffolding protein family member 2 , Crk-associated substrate related protein Cas-L , Enhancer of filamentation 1 p55 , cas-like docking , enhancer of filamentation 1 , neural precursor cell expressed developmentally down-regulated protein 9 , p130Cas-related protein , renal carcinoma antigen NY-REN-12 , neural precursor cell expressed, developmentally down-regulated gene 9 , CRK-associated substrate-related protein , Crk-associated substrate lymphocyte-specific protein , NEDD-9 , mEF1 , p105

GENE ID SPECIES
395736 Gallus gallus
462433 Pan troglodytes
100063890 Equus caballus
100154178 Sus scrofa
100229910 Taeniopygia guttata
100606649 Nomascus leucogenys
4739 Homo sapiens
291044 Rattus norvegicus
18003 Mus musculus
488220 Canis lupus familiaris
Selected quality suppliers for anti-NEDD9 (NEDD9) Antibodies
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