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Neurochondrin Proteins (NCDN)

NCDN encodes a leucine-rich cytoplasmic protein, which is highly similar to a mouse protein that negatively regulates Ca/calmodulin-dependent protein kinase II phosphorylation and may be essential for spatial learning processes. Additionally we are shipping Neurochondrin Antibodies (57) and Neurochondrin Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NCDN 23154 Q9UBB6
NCDN 26562 Q9Z0E0
NCDN 89791 O35095
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Top Neurochondrin Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$4,126.83
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details

NCDN Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus) ,

More Proteins for Neurochondrin (NCDN) Interaction Partners

Human Neurochondrin (NCDN) interaction partners

  1. Schizophrenia subjects compared to controls showed a marked increase in CA1 (show CA1 Proteins) hippocampal Norbin, and Tamalin (show GRASP Proteins) proteins (47% and 34% respectively), which are endogenous regulators of mGluR5 (show GRM5 Proteins) signalling and trafficking

  2. we demonstrate that neurochondrin has strong isoform selectivity towards the RIIa subunit of PKA with nanomolar affinity

  3. In silico screening for palmitoyl substrates reveals a role for DHHC1/3/10 (zDHHC1/3/11)-mediated neurochondrin palmitoylation in its targeting to Rab5 (show RAB5A Proteins)-positive endosomes.

  4. In mouse, the encoded protein is a negative regulator of Ca/calmodulin-dependent protein kinase II phosphorylation and is essential for the spatial learning process.

Mouse (Murine) Neurochondrin (NCDN) interaction partners

  1. A novel mechanism of P-Rex1 regulation through the GPCR (show GPBAR1 Proteins)-adaptor protein Norbin.

  2. Norbin is a regulator of adult hippocampal neurogenesis and that its deletion causes depressive-like behaviors.

  3. In silico screening for palmitoyl substrates reveals a role for DHHC1/3/10 (zDHHC1/3/11)-mediated neurochondrin palmitoylation in its targeting to Rab5 (show RAB5A Proteins)-positive endosomes.

  4. study reports that Norbin, a neuron-specific protein, physically interacts with mGluR5 (show GRM5 Proteins) in vivo, increases the cell surface localization of the receptor, and positively regulates mGluR5 (show GRM5 Proteins) signaling

  5. neurochondrin/norbin gene function is essential for the early embryogenesis

  6. Neurochondrin expression pattern in the developing and adult brain.

  7. results showed that neurochondrin is a negative regulator of Ca(2+)/calmodulin-dependent protein kinase II phosphorylation and specific homozygous gene disruption resulted in epileptic seizure

Neurochondrin (NCDN) Protein Profile

Protein Summary

This gene encodes a leucine-rich cytoplasmic protein, which is highly similar to a mouse protein that negatively regulates Ca/calmodulin-dependent protein kinase II phosphorylation and may be essential for spatial learning processes. Several alternatively spliced transcript variants of this gene have been described.

Gene names and symbols associated with Neurochondrin Proteins (NCDN)

  • CG2330 gene product from transcript CG2330-RA (Neurochondrin)
  • neurochondrin (NCDN)
  • neurochondrin homolog (Neurochondrin)
  • neurochondrin (ncdn)
  • neurochondrin (Ncdn)
  • AU042419 protein
  • CG2330 protein
  • Dmel\\CG2330 protein
  • GB14786 protein
  • mKIAA0607 protein
  • MMS10-AE protein
  • Ms10ae protein
  • NCDN protein
  • Norbin protein

Protein level used designations for Neurochondrin Proteins (NCDN)

neurochondrin , CG2330-PA , Neurochondrin-PA , dNeurochondrin , neurochondrin homolog , neurochondrin-like , M-Sema F-associating protein of 75 kDa , minisatellite 10ae detected by probe MMS10 , neurochondrin-1 , neurochondrin-2 , neurite outgrowth-related protein from the rat brain

GENE ID SPECIES
40796 Drosophila melanogaster
456743 Pan troglodytes
552430 Apis mellifera
571005 Danio rerio
100415247 Callithrix jacchus
100443801 Pongo abelii
23154 Homo sapiens
475339 Canis lupus familiaris
505994 Bos taurus
26562 Mus musculus
89791 Rattus norvegicus
419633 Gallus gallus
100734636 Cavia porcellus
494655 Xenopus laevis
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