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Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. Additionally we are shipping and many more products for this protein.
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These data indicate that Net1A acetylation regulates its subcellular localization to impact on RhoA activity and actin cytoskeletal organization.
Data identify for the first time a role for NET1 in vivo and indicate that NET1 expression is essential for the proliferation and differentiation of mammary epithelial cells in the developing mammary gland.
NET1 has roles in stimulating cytoskeletal reorganization and in transforming cells
PAK1 (show PAK1 Antibodies) negatively regulates the activity of NET1
Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway. Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death.
neuroepithelial cell transforming gene 1
, neuroepithelial cell-transforming gene 1 protein
, Net1 homolog
, guanine nucleotide regulatory protein (oncogene)
, rho guanine nucleotide exchange factor 8