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anti-Neurofilament, Heavy Polypeptide (NEFH) Antibodies

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Additionally we are shipping Neurofilament, Heavy Polypeptide Kits (33) and Neurofilament, Heavy Polypeptide Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NEFH 380684 P19246
NEFH 24587  
NEFH 4744 P12036
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Top anti-Neurofilament, Heavy Polypeptide Antibodies at antibodies-online.com

Showing 10 out of 422 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IHC (fro), IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$313.50
Details
Human Mouse Un-conjugated ELISA (Capture), EIA, IHC (fro), WB 0.1 mg Log in to see 6 to 8 Days
$286.00
Details
Chicken Mouse Un-conjugated IHC (fro), IF, IHC (p), WB   0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Cow Mouse Un-conjugated IHC (fro), IHC (p), WB   1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Mouse Un-conjugated WB NEFH monoclonal antibody (M01), clone 2E8 Western Blot analysis of NEFH expression in HeLa. Detection limit for recombinant GST tagged NEFH is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
All Species Mouse Un-conjugated EIA, IHC (fro), IF, IHC (p), WB   0.2 mg Log in to see 6 to 8 Days
$500.50
Details
All Species Mouse Un-conjugated IHC (fro), IF, IHC (p), WB   0.1 mg Log in to see 6 to 8 Days
$286.00
Details
Human Mouse Un-conjugated IHC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Immunohistochemical analysis of paraffin-embedded medulla oblongata tissues using NEFH mouse mAb with DAB staining. 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded rat brain labeled with Anti-NF-H Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat brain labeled with Anti-NF-H Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 14 to 21 Days
$269.50
Details
Chicken Mouse Un-conjugated IHC (fro), IF, WB 0.1 mL Log in to see 6 to 8 Days
$357.50
Details

NEFH Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Neurofilament, Heavy Polypeptide Antibodies

  1. Human Monoclonal NEFH Primary Antibody for ELISA (Capture), EIA - ABIN614809 : Côté, Collard, Julien: Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: a mouse model of amyotrophic lateral sclerosis. in Cell 1993 (PubMed)
    Show all 7 references for ABIN614809

  2. Human Monoclonal NEFH Primary Antibody for WB - ABIN393231 : Shrestha, Irvin, Taylor, Wiener, Pajewski, Haritunians, Delaney, Schambelan, Polak, Arnett, Chen, Grunfeld: A genome-wide association study of carotid atherosclerosis in HIV-infected men. in AIDS 2010 (PubMed)
    Show all 5 references for ABIN393231

  3. Chicken Monoclonal NEFH Primary Antibody for IHC (fro), IF - ABIN371826 : Harris, Ayyub, Shaw: A molecular dissection of the carboxyterminal tails of the major neurofilament subunits NF-M and NF-H. in Journal of neuroscience research 1992 (PubMed)
    Show all 3 references for ABIN371826

  4. Chicken Monoclonal NEFH Primary Antibody for IHC (fro), IF - ABIN112360 : Bauwens, De Groot, Ramaekers, Veldman, Huizing: Expression of intermediate filament proteins in the adult human vestibular labyrinth. in The Annals of otology, rhinology, and laryngology 1992 (PubMed)
    Show all 2 references for ABIN112360

  5. Human Monoclonal NEFH Primary Antibody for IHC (fro), IHC (p) - ABIN1108414 : Lees, Shneidman, Skuntz, Carden, Lazzarini: The structure and organization of the human heavy neurofilament subunit (NF-H) and the gene encoding it. in The EMBO journal 1988 (PubMed)
    Show all 2 references for ABIN1108414

  6. Human Monoclonal NEFH Primary Antibody for IHC, ELISA - ABIN1098127 : Singh, Yan, Hull, Read, OSullivan, Henderson, Rose, Greer, McCombe: Levels of phosphorylated axonal neurofilament subunit H (pNfH) are increased in acute ischemic stroke. in Journal of the neurological sciences 2011 (PubMed)
    Show all 2 references for ABIN1098127

  7. Human Polyclonal NEFH Primary Antibody for IF (p), IHC (p) - ABIN2177936 : Liu, Nie, Zhao, Zhang, Zhang, Wang, Cheng: Conserved dopamine neurotrophic factor-transduced mesenchymal stem cells promote axon regeneration and functional recovery of injured sciatic nerve. in PLoS ONE 2014 (PubMed)

  8. All Species Monoclonal NEFH Primary Antibody for EIA, IHC (fro) - ABIN111967 : Lukás, Dráber, Bucek, Dráberová, Viklický, Dolezel: Expression of phosphorylated high molecular weight neurofilament protein (NF-H) and vimentin in human developing dorsal root ganglia and spinal cord. in Histochemistry 1994 (PubMed)

  9. Cow (Bovine) Monoclonal NEFH Primary Antibody for IHC (fro), IHC (p) - ABIN126023 : Hacker, Polak, Springall, Ballesta, Cadieux, Gu, Trojanowski, Dahl, Marangos: Antibodies to neurofilament protein and other brain proteins reveal the innervation of peripheral organs. in Histochemistry 1985 (PubMed)

More Antibodies against Neurofilament, Heavy Polypeptide Interaction Partners

Mouse (Murine) Neurofilament, Heavy Polypeptide (NEFH) interaction partners

  1. Data conclude that NF-H and NF-M (show CEBPB Antibodies) C-terminal domains do not normally regulate NF transport rates as previously proposed, but instead increase the proteolytic resistance of NF, thereby stabilizing the stationary neurofilament cytoskeleton along axons.

  2. plasma NfH levels closely reflect later stages of disease progression and therapeutic response in the SOD1 (show SOD1 Antibodies)(G93A) mouse model of amyotrophic lateral sclerosis

  3. NFH expression reveals an exquisite level of Cb stripe complexity that respects the transverse zone divisions and delineates an intricately patterned target field for Cb afferents.

  4. results obtained in mouse model for leprous neuropathy indicate biochemical alterations in neurofilaments, i.e., hyperphosphorylation of NF-H and NF-M (show CEBPB Antibodies)

  5. Overexpression of peripherin (show PRPH Antibodies) in mice deficient for neurofilament light (NF-L (show NEFL Antibodies)) subunits induced a progressive ALS-like spinal motor neuron degeneration (show CLN8 Antibodies) prevented by simultaneous overexpression of NF-H

  6. NF-H regulates the association of NFs with kinesin. Phosphorylation of NF-H dissociates NFs from kinesin and provides a mechanism by which NF-H phosphorylation can contribute to the slowing of NF axonal transport.

  7. Alpha-internexin (show INA Antibodies) coassembles with all 3 neurofilament proteins into a single network of filaments in quadruple-transfected cells. Deleting NF-M (show CEBPB Antibodies) alone or together with NF-H in mice reduces alpha-internexin (show INA Antibodies) transport & content in axons throughout the CNS.

  8. We have validated the serum pNF-H assay as an unbiased measurement of axonal injury in EAE, facilitating rapid screening of potential neuroprotective therapies in this model.

  9. RE1 silencing transcription factor (REST) plays a contributory role in the neuron-specific expression of the alpha-internexin (show INA Antibodies), NF-H and NF-M (show CEBPB Antibodies) genes

Human Neurofilament, Heavy Polypeptide (NEFH) interaction partners

  1. Studied diagnostic Value of Serum Levels of GFAP (show GFAP Antibodies), pNF-H, and NSE (show ENO2 Antibodies) Compared With Clinical Findings in Severity Assessment of Human Traumatic Spinal Cord Injury.

  2. This study demonstrated that Higher NF-L (show NEFL Antibodies) concentrations (beta = -0.26) were associated with functional decline in patients with vascular burden.

  3. Phospho-NFH levels were significantly higher in amyotrophic lateral sclerosis patients in comparison with controls, in particular in fast progressors.

  4. Data identified NEFH methylation as a candidate epigenetic marker for prognosis of RCC patients as well as prediction of anti-vascular endothelial growth factor-based therapy response.

  5. Subconcussive repetitive trauma in amateur boxing causes a mild traumatic brain injury that may be diagnosed by CSF (show CSF2 Antibodies) analysis of expressed pNFH, even without unconsciousness or concussion symptoms.

  6. Absence of axonal neurofilaments in NFH-LacZ (show GLB1 Antibodies) transgenic mice compromises axonal regeneration.

  7. CSF (show CSF2 Antibodies) and intrathecal levels and CSF (show CSF2 Antibodies)/serum ratios of anti-NFH antibodies were increased in the CIS (show CISH Antibodies) patients early developing multiple sclerosis.

  8. These data support further study of pNF-H in CSF (show CSF2 Antibodies), serum and plasma as a potential amyotrophic lateral sclerosis biomarker

  9. NF-H levels increase significantly faster in children who have a worse Glasgow Outcome Scale following traumatic brain injury, or died.

  10. significant in vivo information on the pathophysiology of stroke may be obtained by the determination of NfH(SMI35).

Neurofilament, Heavy Polypeptide (NEFH) Antigen Profile

Protein Summary

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.

Gene names and symbols associated with NEFH

  • neurofilament heavy polypeptide (MCYG_06231) antibody
  • neurofilament, heavy polypeptide (Nefh) antibody
  • neurofilament, heavy polypeptide (NEFH) antibody
  • mKIAA0845 antibody
  • NEFH antibody
  • NF-H antibody
  • NF200 antibody
  • NFH antibody

Protein level used designations for NEFH

neurofilament heavy polypeptide , 200 kDa neurofilament protein , neurofilament 200kDa , neurofilament triplet H protein , NF-H , neurofilament, heavy polypeptide 200kDa , neurofilament, heavy polypeptide , neurofilament, heavy polypeptide 200kDa-like , heavy neurofilament protein , intermediate filament protein

GENE ID SPECIES
9222506 Arthroderma otae CBS 113480
380684 Mus musculus
24587 Rattus norvegicus
4744 Homo sapiens
100156492 Sus scrofa
528842 Bos taurus
442940 Canis lupus familiaris
417020 Gallus gallus
100716406 Cavia porcellus
101107472 Ovis aries
101087272 Felis catus
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