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Neurogenin 3 Proteins (NEUROG3)

The protein encoded by NEUROG3 is a basic helix-loop-helix (bHLH) transcription factor involved in neurogenesis. Additionally we are shipping Neurogenin 3 Antibodies (111) and Neurogenin 3 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NEUROG3 50674 Q9Y4Z2
NEUROG3 11925 P70661
Rat NEUROG3 NEUROG3 60329  
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Top Neurogenin 3 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$809.60
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 3 to 4 Days
$388.93
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HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$983.48
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

NEUROG3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

More Proteins for Neurogenin 3 (NEUROG3) Interaction Partners

Xenopus laevis Neurogenin 3 (NEUROG3) interaction partners

  1. These results provide new detail regarding the Ngn3 transcriptional network operating in endocrine progenitor cells to specify a beta (show SUCLA2 Proteins) cell phenotype

Human Neurogenin 3 (NEUROG3) interaction partners

  1. ChIP experiments confirmed that Pdx1 (show PDX1 Proteins) activates the expression of the downstream transcription factors, Ngn3 and Pax6 (show PAX6 Proteins), by combined with the promoter regions of insulin (Insulin (show INS Proteins)-P), Ngn3 (Ngn3-P), and Pax6 (Pax6 (show PAX6 Proteins)-P).

  2. NGN3 expression in the adult human exocrine pancreas marks a dedifferentiating cell population.

  3. conclude that NEUROG3 is essential for endocrine pancreas development in humans and that as little as 10% NEUROG3 is sufficient for formation of pancreatic endocrine cells

  4. NEUROG3 deficiency produces a rare clinical syndrome characterised by severe malabsorptive diarrhoea from early life and mild diabetes with a variable age of onset.

  5. Activation of the developmental pathway neurogenin-3/microRNA-7a regulates cholangiocyte proliferation in response to injury.

  6. The expression of transcription factor Ngn3 and pancreatic mesenchymal microenvironment are important and necessary to promote pancreatic progenitors differentiated to islet cells regardless of pancreatic development or islets regeneration.

  7. Recessively inherited NEUROG-3 mutations were originally identified in three patients with unexplained congenital malabsorptive diarrhea and an absence of EC.

  8. Prospectively isolated NGN3-expressing progenitors from human embryonic stem cells give rise to pancreatic endocrine cells.

  9. Data indicate associations of SNPs in eight loci CXCR4, HHEX, FOXA2, NGN3, TCF7L2, FLJ39370 (C4orf32), LOC646279 (RPL21P7) and THADA with body mass index (BMI) and weight.

  10. Ngn3-mediated pancreatic duct-to-endocrine cell reprogramming was measured employing genome wide mRNA profiling.

Mouse (Murine) Neurogenin 3 (NEUROG3) interaction partners

  1. Duplication of pre-existing beta-cells is not the sole source of new beta-cells during pregnancy; Ngn3 may be involved in this process.

  2. data demonstrate that HIF1-alpha (show HIF1A Proteins) negatively controls beta cell differentiation in vivo by regulating NGN3 expression, and that this effect is mediated by signals from blood vessels.

  3. Data indicate that all neurogenin 3 (Neurog3)-tuberous sclerosis complex 1 (Tsc1 (show TSC1 Proteins))-/- mice developed notable adenocarcinoma-like lesions in pancreas starting from the age of 100 days old.

  4. Activation of the developmental pathway neurogenin-3/microRNA-7a regulates cholangiocyte proliferation in response to injury.

  5. Hnf1b plays a crucial role in the regulatory networks that control pancreatic MPC expansion, acinar cell identity, duct morphogenesis and generation of endocrine precursors.

  6. The role of neurogenin 3 and PD-L1 (show CD274 Proteins) in the genesis of neo-islets in NOD mice is reported.

  7. Neurog3 establishes the posterior boundary of the serotonergic system by actively suppressing serotonergic specification in the spinal cord.

  8. Insm1 (show INSM1 Proteins) works to promote endocrine cell differentiation in a pathway that involves Neurog3 and Ripply3 (show DSCR6 Proteins)

  9. three transcription factors, PDX1 (show PDX1 Proteins), NGN3 and MAFA (show MAFA Proteins), are very important in pancreatic development. Overexpression of these three factors can reprogram both pancreatic exocrine and SOX9 (show SOX9 Proteins)-positive cells of the liver into cells resembling pancreatic beta cells

  10. The role of Ngn3 in the specification of hypothalamic neurons controlling energy balance, is reported.

Zebrafish Neurogenin 3 (NEUROG3) interaction partners

  1. The control of endocrine cell fate is instead fulfilled by two basic helix-loop-helix factors, Ascl1b and Neurod1 (show NEUROD1 Proteins) and NEUROG3 is not the unique pancreatic endocrine cell fate determinant in vertebrates.

  2. Nkx2.2 coordinately activates NeuroD1 with Ngn3 in the endocrine progenitor cell and plays a role in the maintenance of NeuroD1 expression to regulate beta cell function in the mature islet.

Neurogenin 3 (NEUROG3) Protein Profile

Protein Summary

The protein encoded by this gene is a basic helix-loop-helix (bHLH) transcription factor involved in neurogenesis. The encoded protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of congenital malabsorptive diarrhea 4 (DIAR4).

Gene names and symbols associated with Neurogenin 3 Proteins (NEUROG3)

  • neurogenin 3 (NEUROG3)
  • neurogenin 3 (neurog3)
  • neurogenin-3 (Tsp_02556)
  • neurogenin 3 (Neurog3)
  • neurogenin 3 (NGN3)
  • atoh4 protein
  • Atoh5 protein
  • bHLHa7 protein
  • Math4B protein
  • neurog3 protein
  • NGN-3 protein
  • ngn2 protein
  • Ngn3 protein
  • ngn3a protein
  • Relax protein

Protein level used designations for Neurogenin 3 Proteins (NEUROG3)

neurogenin 3 , neurogenin-3 , class A basic helix-loop-helix protein 7 , protein atonal homolog 5 , NGN-3 , Neurogenin 3 (Atonal protein homolog 5) (Helix-loop-helix protein mATH-4B) (MATH4B) , atonal homolog 5 , helix-loop-helix protein mATH-4B , transcriptional regulator, Relax , Zath4b , atonal homolog 4

GENE ID SPECIES
711583 Macaca mulatta
748874 Pan troglodytes
100038294 Xenopus (Silurana) tropicalis
100188927 Xenopus laevis
100461771 Pongo abelii
10898849 Trichinella spiralis
50674 Homo sapiens
11925 Mus musculus
60329 Rattus norvegicus
489022 Canis lupus familiaris
540130 Bos taurus
780450 Ovis aries
114411 Danio rerio
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