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NGB encodes an oxygen-binding protein that is distantly related to members of the globin gene family. Additionally we are shipping Neuroglobin Kits (51) and Neuroglobin Proteins (22) and many more products for this protein.
Showing 10 out of 83 products:
Human Polyclonal Neuroglobin Primary Antibody for EIA, IHC (fro) - ABIN115511
Pesce, Bolognesi, Bocedi, Ascenzi, Dewilde, Moens, Hankeln, Burmester: Neuroglobin and cytoglobin. Fresh blood for the vertebrate globin family. in EMBO reports 2002
Show all 8 references for ABIN115511
Data show that the neuroglobin (Ngb) protein was downregulated in the retinal ganglion cells after optic nerve injury.
Overexpression of neuroglobin reduced sensorimotor deficits following TBI. An endogenous increase in neuroglobin expression occurs during the subacute period. Increasing neuroglobin expression during the acute period after TBI may improve recovery.
reflect lesser perturbations produced by acute inhalation of combustion smoke in the Ngb overexpressing mouse, suggesting that Ngb mitigates mitochondrial dysfunction and neurotoxicity and raises the threshold of smoke inhalation-induced brain injury
A critical role for neuroglobin is demonstrated via its differential interaction with phosphatase and tensin homolog (PTEN (show PTEN Antibodies)) and Akt (show AKT1 Antibodies) during neurite induction.
Neuroglobin overexpression resulted in a significant reduction in infarct volume 24 hours after brain ischemia.
Ngb overexpression can inhibit oxygen-glucose deprivation-induced mitochondria permeability transition opening in primary cultured mouse cortical
CREB (show CREB1 Antibodies) may also mediate transcriptional regulation of neuroglobin gene.
Ngb deficiency neither affected the level of Melanopsin (show OPN4 Antibodies) and Tyrosine Hydroxylase (show TH Antibodies) proteins nor the intactness of PACAP (show ADCYAP1 Antibodies)-positive retinohypothalamic projections in the suprachiasmatic nucleus.
This study demonistrated that Ngb over-expression reduced traumatic lesion volume.
mitochondria distribution of Ngb is clearly associated with and may contribute to Ngb's neuroprotection.
Study characterized the presence of Ngb (show GTPBP4 Antibodies) in the human cochlea
Data show that the mean peak serum neuroglobin and Nogo-A concentrations were both significantly higher in patients with an unfavorable outcome at 6 months after traumatic brain injury (TBI).
Neuroglobin player role in estrogen receptor alpha (show ESR1 Antibodies)-positive cancer cell viability.
a mechanism for redox control of human Ngb (show GTPBP4 Antibodies) (hNgb) activity
17beta-estradiol-induced NGB (show GTPBP4 Antibodies) up-regulation could act as an oxidative stress sensor, which does not oppose to the pro-apoptotic 17beta-estradiol effect in ER beta (show ESR2 Antibodies)-containing colon cancer cells unless a rise of oxidative stress occurs.
first X-ray structure of wild-type human neuroglobin is reported at 1.74 A resolution
Glu60 of human Ngb (show GTPBP4 Antibodies) is a crucial residue for its GDI and neuroprotective activities
Data show that chimeric neuroglobin and myoglobin (show MB Antibodies) were generated by swapping a regulatory segment.
This paper for the first time presents the data on neuroglobin distribution in human cerbellum using immunohistochemistry.
Findings indicate that myoglobin (Mb (show MB Antibodies)) and neuroglobin (Ngb) can be expressed in nonmuscle and non-neural contexts.
Constitutive expression levels of neuroglobin in neonatal brain cells may explain mild neuronal injury after 60 min. of deep hypothermic circulatory arrest.
Ngb overexpression may have potential therapeutic benefits for both reducing secondary damages and improving the outcomes after traumatic spinal cord injury
The zebrafish Neuroglobin can catalyze the reduction of nitrite to nitric oxide with a broad range of reaction rate constants.
Data show that the neuroglobin (Ngb) protein was upregulated in the amacrine cells after optic nerve injury.
Chimeric Myoglobin (show MB Antibodies) has a cell-membrane-penetrating activity similar to zebrafish Ngb.
Neuroglobin appears to be associated with mitochondria-rich cell types and thus oxygen consumption rates, suggesting a myoglobin (show MB Antibodies)-like function of this protein in facilitated oxygen diffusion
both zebrafish and chimeric ZHHH Ngb can penetrate cell membranes in the absence of Chariot
This gene encodes an oxygen-binding protein that is distantly related to members of the globin gene family. It is highly conserved among other vertebrates. It is expressed in the central and peripheral nervous system where it may be involved in increasing oxygen availability and providing protection under hypoxic/ischemic conditions.
, GTP binding protein 3
, GTP-binding protein NGB
, Nucleolar GTP-binding protein 1 (Chronic renal failure gene protein) (GTP-binding protein NGB)
, chronic renal failure gene protein
, chronic renal failure protein
, nucleolar GTP-binding protein 1