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Neuromedin B receptor binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissue. Additionally we are shipping NMBR Antibodies (49) and and many more products for this protein.
In sow estrous cycle, the hypothalamic levels of both NMB and NMBR mRAN were similar, but the expression levels of the pituitary were negatively correlated.
The rs2717 and rs6926279 within the NMBR gene were associated with schizophrenia liability.
Hypoxia regulates the expression of the neuromedin B receptor through a mechanism dependent on hypoxia-inducible factor-1alpha.
NMB and its receptor are coexpressed by proliferating cells in which they act in an autocrine fashion with similar and modest potency in both normal and malignant colonic epithelial cells.
mice with deletion of NB receptor have lower insulinemia, especially in response to oral glucose, and females also exhibited a better glucose tolerance, suggesting the involvement of neuromedin b and its receptor in regulation of insulin (show INS ELISA Kits) secretion induced by incretins, and also, in insulin (show INS ELISA Kits) sensitivity.
ablating NMB receptor-expressing neurons eliminated basal and hypoxia-induced sighing, but left breathing otherwise intact initially
The neuromedin B pathways are importantly involved in secretory pathways of TSH and revealed its participation in the in vivo regulation of gene expression of TSH beta (show TSHB ELISA Kits)-subunit (show POLG ELISA Kits) and pituitary MCT8 (show MCT8 ELISA Kits) and Thrb (show THRB ELISA Kits) and hypothalamic TRH (show TRH ELISA Kits) and type 2 deiodinase (show DIO2 ELISA Kits).
Together, we define the respective function of NMBR and GRPR (show GRPR ELISA Kits) in itch transmission, and reveal an unexpected relationship not only between the two receptors but also between the two populations of interneurons in itch signaling.
spinal GRPr (show GRPR ELISA Kits) and NMBr independently drive itch neurotransmission in mice.
Results implicate that NMB is involved in cartilage development, either in an autocrine or paracrine manner.
The data demonstrated that the neuromedin B-neuromedian B receptor interaction in pregnant myometrial primary cells in vitro predominantly influenced uterine activity through regulation of Il6 (show IL6 ELISA Kits) expression via the Rela/p65 (show NFkBP65 ELISA Kits) pathway.
These data demonstrate that neuromedin B and its receptor can induce the onset of labor via a RELA (show NFkBP65 ELISA Kits)/IL6 (show IL6 ELISA Kits)-mediated pathway.
The mRNA and protein expressions of NMBR reach a peak at the onset of labor.
disruption of the neuromedin B receptor pathway did not change body weight homeostasis in female mice fed a normolipid diet
Neuromedin B receptor binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissue.
neuromedin B receptor
, neuromedin-B receptor
, epididymis tissue protein Li 185a
, neuromedin-B-preferring bombesin receptor