anti-Neuronal Calcium Sensor 1 (NCS1) Antibodies

NCS1 is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. Additionally we are shipping NCS1 Proteins (14) and NCS1 Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NCS1 65153 P62168
NCS1 23413 P62166
NCS1 14299 Q8BNY6
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Top anti-NCS1 Antibodies at

Showing 10 out of 82 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB <b>WB Suggested Anti-FREQ Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
Cow Rabbit Un-conjugated IHC, WB Immunohistochemistry with Small intestine, myetneric plexus tissue at an antibody concentration of 5-10µg/ml using anti-FREQ antibody (ARP34711_P050) 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IHC (p), WB FREQ Antibody (N-term) (ABIN658493) western blot analysis in CEM cell line lysates (35 µg/lane). This demonstrates the FREQ antibody detected the FREQ protein (arrow). 400 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of NCS1 Antibody (Center) (ABIN388386) in MCF-7 cell line lysates (35 µg/lane). NCS1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human breast carcinoma reacted with NCS1 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated EIA 0.4 mL Log in to see 6 to 8 Days
Human Mouse Un-conjugated IF, WB Western blot analysis of NCS-1 on a rat cerebrum lysate. Lane 1: 1:500, lane 2: 1:1000, lane 3: 1:2000 dilution of the anti- NCS-1 antibody. 50 μg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image Sample(30 μg of whole cell lysate) A:A431, B:Hep G2, 12% SDS PAGE antibody diluted at 1:200 IHC-P Image NCS1 antibody detects NCS1 protein at on mouse fore brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse fore brain. NCS1 antibody , dilution: 1:500. 100 μL Log in to see 1 to 2 Days
Mouse Rabbit Un-conjugated WB 100 μg Log in to see 1 to 2 Days
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Western Blot: Frequenin Antibody [NBP1-89820] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Negative control (vector only transfected HEK293T lysate).Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cell) Western Blot: Frequenin Antibody [NBP1-89820] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10.Lane 2: Human Cerebral Cortex tissue 0.1 mL Log in to see 10 to 13 Days
Human Chicken Un-conjugated ICC, IF, ELISA, WB 0.2 mg Log in to see 7 to 9 Days

NCS1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-NCS1 Antibodies

  1. Human Monoclonal NCS1 Primary Antibody for IF, WB - ABIN968601 : Braunewell, Gundelfinger: Intracellular neuronal calcium sensor proteins: a family of EF-hand calcium-binding proteins in search of a function. in Cell and tissue research 1999 (PubMed)
    Show all 4 Pubmed References

  2. Cow (Bovine) Polyclonal NCS1 Primary Antibody for IHC, WB - ABIN2775722 : OCallaghan, Burgoyne: Identification of residues that determine the absence of a Ca(2+)/myristoyl switch in neuronal calcium sensor-1. in The Journal of biological chemistry 2004 (PubMed)

  3. Cow (Bovine) Polyclonal NCS1 Primary Antibody for IHC, WB - ABIN2775968 : Szafranski, Schindler, Taudien, Hiller, Huse, Jahn, Schreiber, Backofen, Platzer: Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns. in Genome biology 2008 (PubMed)

More Antibodies against NCS1 Interaction Partners

Human Neuronal Calcium Sensor 1 (NCS1) interaction partners

  1. Results show that although NCS-1 Var2mRNA can be detected, protein expression was not detectable. When overexpressed in cell lines NCS-1 Var2 appears to be folded properly, yet it has a lower calcium affinity. Because most NCS-1 binding to its protein partners requires calcium binding, it is unlikely that NCS-1 Var2 would play a major regulatory role in cells.

  2. structural and dynamical response of NCS-1 protein to elevated temperature may be one of its intrinsic functional properties

  3. Lithium normalizes gamma band oscillations mediated by P/Q-type calcium channels modulated by NCS-1.

  4. Study determined the salient features of the folding free-energy landscapes of the Mg2 (show MUC7 Antibodies)+-bound and apo (show C9orf3 Antibodies) states of NCS-1

  5. results reveal the important role of salt bridges on the structural properties of NCS-1 protein and that R102Q mutation disables the dynamic relocation of C-terminus, which may block the binding of NCS-1 protein to its receptors

  6. single-molecule optical tweezers were used to monitor misfolding reactions of the human neuronal calcium sensor-1.

  7. A strong liason was characterized between myristoylation and cryptic EF-1 (show EEF1D Antibodies) in NCS-1.

  8. The functional link in substantia nigra dopamine neurons between Cav1.3 (show CACNA1D Antibodies)- L-type-Ca2 (show CA2 Antibodies)+ channels and D2-autoreceptor activity is an adaptive signalling network controlled by NCS-1.

  9. NCS1 has evolved a remarkable complex interdomain cooperativity and a fundamentally different folding mechanism compared to structurally related proteins.

  10. data suggest that genetic variants in the NCS-1 gene contribute to susceptibility of Cocaine Abuse in individuals of African descent.

Mouse (Murine) Neuronal Calcium Sensor 1 (NCS1) interaction partners

  1. Phosphorylation of CaMKII-alpha, known to trigger long-term potentiation and increase BDNF levels, was significantly reduced in the Ncs1-/- mouse brain. Further, electric potential stimulation, which increases the levels of BDNF and promotes spatial learning, significantly increased the levels of NCS-1 concomitant with phosphorylated CaMKII-alpha in the hippocampus; suggesting a close relationship between NCS-1 and CaM...

  2. these data demonstrate that NCS-1 contributes to stress tolerance in cardiomyocytes at least in part by activating certain Ca(2 (show CA2 Antibodies)+)-dependent survival pathways that promote mitochondrial biosynthesis/function and detoxification pathways.

  3. These studies identify novel roles for NCS-1 in regulating activity-dependent striatal dopamine release and aspects of motivated behavior

  4. elevated expression of neuronal calcium sensor 1 (Ncs1) and dopamine type-2 receptors upon self-directed exploration, is reported.

  5. IGF-1 (show IGF1 Antibodies) strengthens the interaction between NCS-1 and IP3R (show ITPR1 Antibodies) in the process of regulation of nuclear Ca2 (show CA2 Antibodies)+ signaling in cardiomyocytes.

  6. data implicate NCS-1 in exploratory activity, memory and mood-related behaviors, suggesting that NCS-1 gene ablation may result in phenotypic abnormalities associated with neuropsychiatric disorders

  7. NCS-1 transgene is upregulated in hypertrophic hearts, while hormone-induced hypertrophy is largely prevented in Ncs1-deficient hearts.

  8. NCS-1 is an accessory subunit of Kv4 (show KCNC1 Antibodies)-encoded I(to,f) channels that functions to regulate I(to,f) density in the mammalian myocardium.

  9. PI 4-kinase functions to negatively regulate GLUT4 (show SLC2A4 Antibodies) translocation through its interaction with NCS-1.

  10. NCS-1 should be considered an important potential Kv4 (show KCNC1 Antibodies) regulatory subunit, particularly in the immature heart.

Cow (Bovine) Neuronal Calcium Sensor 1 (NCS1) interaction partners

  1. C-terminal segment of NCS1 regulates reuptake of myristoyl group under Ca(2 (show CA2 Antibodies)+)-free conditions and participates in organization of the target-binding pocket of the protein. We show putative role of NCS1 in photoreceptors as a modulator of GRK (show GRK4 Antibodies) activity

  2. NCS-1-ARF1 (show ARF1 Antibodies) interaction provides evidence for functional cross-talk between Ca(2 (show CA2 Antibodies)+)-dependent and ARF (show CDKN2A Antibodies)-dependent pathways in TGN (show TG Antibodies) to plasma membrane traffic

  3. Frequenin (BovFrq) native to the bovine hippocampus has been purified, sequenced for its 9 internal fragments, cloned, and studied.

Zebrafish Neuronal Calcium Sensor 1 (NCS1) interaction partners

  1. findings reveal a novel signalling pathway involved in development of the semicircular canal system, and suggest a previously unrecognized role for NCS-1 in mitochondrial function via its association with several mitochondrial proteins.

NCS1 Antigen Profile

Protein Summary

This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with NCS1

  • neuronal calcium sensor 1 (NCS1) antibody
  • frequenin homolog (freq) antibody
  • neuronal calcium sensor 1 (ncs1) antibody
  • calcium sensor-1 (cse-1) antibody
  • neuronal calcium sensor 1 (MGYG_03475) antibody
  • calcium-binding protein NCS-1 (PGTG_09250) antibody
  • neuronal calcium sensor 1 (Tsp_06748) antibody
  • Neuronal calcium sensor 1 (ncs1) antibody
  • neuronal calcium sensor 1 (Ncs1) antibody
  • neuronal calcium sensor 1 L homeolog (ncs1.L) antibody
  • neuronal calcium sensor 1a (ncs1a) antibody
  • Neuronal calcium sensor 1 (ncs-1) antibody
  • 9430075O15Rik antibody
  • A730032G13Rik antibody
  • AI836659 antibody
  • FLUP antibody
  • Freq antibody
  • freqa antibody
  • LOC100189965 antibody
  • Mfreq antibody
  • MGC75953 antibody
  • NCS-1 antibody
  • xfreq antibody
  • zgc:63620 antibody

Protein level used designations for NCS1

putative frequenin , frequenin homolog , frequenin-like protein , neuronal calcium sensor 1 , NCS-1 , Neuronal calcium sensor 1 , frequenin-like ubiquitous protein , neuronal calcium sensor-1 , frequenin , neuronal calcium sensor homologue , frequenin homolog a , ncs-1a , neuronal calcium sensor-1a

100189965 Taeniopygia guttata
100303592 Saccoglossus kowalevskii
100340886 Oryctolagus cuniculus
394570 Xenopus (Silurana) tropicalis
3873635 Neurospora crassa OR74A
10028582 Arthroderma gypseum CBS 118893
10545012 Puccinia graminis f. sp. tritici CRL 75-36-700-3
10911856 Trichinella spiralis
100172236 Pongo abelii
100380555 Salmo salar
65153 Rattus norvegicus
23413 Homo sapiens
14299 Mus musculus
399297 Xenopus laevis
396336 Gallus gallus
526544 Bos taurus
393437 Danio rerio
180448 Caenorhabditis elegans
Selected quality suppliers for anti-NCS1 (NCS1) Antibodies
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