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Neuronal Growth Regulator 1 Proteins (NEGR1)

glycosylphosphatidylinositol-anchored cell adhesion protein [RGD, Feb 2006].. Additionally we are shipping NEGR1 Antibodies (41) and NEGR1 Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NEGR1 257194 Q7Z3B1
NEGR1 320840 Q80Z24
Rat NEGR1 NEGR1 59318 Q9Z0J8
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Top NEGR1 Proteins at

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Human Cells Mouse His tag 100 μg Log in to see 16 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days

NEGR1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
Mouse (Murine) ,

More Proteins for Neuronal Growth Regulator 1 (NEGR1) Interaction Partners

Human Neuronal Growth Regulator 1 (NEGR1) interaction partners

  1. We observed novel selection signals in CDKAL1 (show CDKAL1 Proteins) and NEGR1, well-known diabetes and obesity susceptibility genes

  2. NEGR1 could be an important locus influencing certain personality dimensions in BN patients.

  3. First study to find an association between an obesity risk gene and differences in white matter integrity. As our subjects were young and healthy, our results suggest that NEGR1 has effects on brain structure independent of its effect on obesity.

  4. Data indicate strong associations with severe obesity for single nucleotide polymorphism (SNP) rs9939609 within the FTO (show FTO Proteins) gene and SNP rs2815752 near the NEGR1 gene.

  5. Results imply a regulatory role for TMEM18 (show TMM18 Proteins), BDNF (show BDNF Proteins), MTCH2 (show MTCH2 Proteins) and NEGR1 in adipocyte differentiation and biology. In addition, we show a variation of MAF (show MAF Proteins) expression during adipogenesis, while NPC1 (show NPC1 Proteins), PTER (show PTER Proteins) and SH2B1 (show SH2B1 Proteins) were not regulated.

  6. Our study supports earlier reports of SH2B1 (show SH2B1 Proteins) to be of importance in insulin (show INS Proteins) sensitivity and, in addition, suggests potential roles of NEGR1 and MTCH2 (show MTCH2 Proteins).

  7. Meta-analysis of 4992 subjects revealed seven SNPs near four loci, including NEGR1, TMEM18 (show TMM18 Proteins), SH2B1 (show SH2B1 Proteins) /ATP2A1 (show ATP2A1 Proteins) and MC4R (show MC4R Proteins), showing significant association at 0.005

  8. Gene-treatment interactions were observed for long-term (NEGR1 rs2815752, Pmetformin*SNP = 0.028; FTO (show FTO Proteins) rs9939609, Plifestyle*SNP = 0.044) weight loss.

  9. Data suggest that in addition to its reported role in the brain, NEGR1 is also expressed in subcutaneous adipose tissue and acts as a central 'hub' in an obesity-related transcript network.

  10. The results of these studies provide supporting evidence for MYEOV and NEGR1 as gene targets of 11q13 gains and 1p31 deletions in a neuroblastoma (show ARHGEF16 Proteins) subset.

Mouse (Murine) Neuronal Growth Regulator 1 (NEGR1) interaction partners

  1. The long non-coding RNA, BC048612, and microRNA-203 were determined to be positive and negative regulators of Negr1 gene expression respectively.

  2. Negr1 controls the development of neurite arborization in vitro and in vivo.

  3. a role of NEGR1 in the control of body weight and food intake

  4. These results suggest a function for neurotractin/kilon as a trans-neural growth-promoting factor for outgrowing axons following hippocampal denervation.

NEGR1 Protein Profile

Protein Summary

glycosylphosphatidylinositol-anchored cell adhesion protein

Gene names and symbols associated with NEGR1

  • neuronal growth regulator 1 (negr1)
  • neuronal growth regulator 1 (NEGR1)
  • neuronal growth regulator 1 (Negr1)
  • 5330422G01Rik protein
  • DMML2433 protein
  • IGLON4 protein
  • KILON protein
  • mKIAA3001 protein
  • NEGR1 protein
  • Ntra protein
  • NTRA-L protein
  • NTRA-S protein
  • zgc:100871 protein

Protein level used designations for NEGR1

neuronal growth regulator 1 , neuronal growth regulator 1-like , IgLON family member 4 , a kindred of IgLON , neurotractin , kindred of IgLON , kilon protein , neurotractin-L , neurotractin-S

445374 Danio rerio
456941 Pan troglodytes
100016404 Monodelphis domestica
100053464 Equus caballus
100127726 Xenopus (Silurana) tropicalis
100380985 Xenopus laevis
100402487 Callithrix jacchus
100595701 Nomascus leucogenys
257194 Homo sapiens
320840 Mus musculus
59318 Rattus norvegicus
395662 Gallus gallus
612706 Canis lupus familiaris
100271880 Sus scrofa
781106 Bos taurus
100174077 Pongo abelii
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