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anti-Neuronal PAS Domain Protein 4 (NPAS4) Antibodies

NXF is a member of the basic helix-loop-helix-PER (MIM 602260)-ARNT (MIM 126110)-SIM (see SIM2\; MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events (Ooe et al., 2004 [PubMed 14701734]).[supplied by OMIM, Mar 2008].. Additionally we are shipping NPAS4 Proteins (4) and NPAS4 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NPAS4 266743 Q8IUM7
NPAS4 266734 Q8CJH6
NPAS4 225872 Q8BGD7
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Top anti-NPAS4 Antibodies at antibodies-online.com

Showing 10 out of 55 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB Host: Rabbit  Target Name: NPAS4  Sample Tissue: Fetal LungLane A:  Primary Antibody Lane B: Primary Antibody + Blocking Peptide Primary Antibody Concentration: 1 µg/mL Peptide Concentration: 5 µg/mL Lysate Quantity: 41 µg/lane/LaneGel Concentration:.12 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Goat Un-conjugated EIA, WB AP23231PU-N NPAS4 antibody staining of Human Frontal Cortex lysate at 0.3 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. AP23231PU-N NPAS4 antibody staining of Mouse (A) and Rat (B) Brain lysates at 1 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Mouse Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using NPAS4 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of NPAS4 staining in HEK293T cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a hidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of NPAS4 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, ELISA 100 μg Log in to see 11 to 16 Days
$412.86
Details
Mouse Mouse HRP ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$422.40
Details
Mouse Mouse FITC ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$426.80
Details
Mouse Mouse Alkaline Phosphatase (AP) ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$429.00
Details

NPAS4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-NPAS4 Antibodies

  1. Cow (Bovine) Polyclonal NPAS4 Primary Antibody for WB - ABIN2779719 : Ooe, Saito, Mikami, Nakatuka, Kaneko: Identification of a novel basic helix-loop-helix-PAS factor, NXF, reveals a Sim2 competitive, positive regulatory role in dendritic-cytoskeleton modulator drebrin gene expression. in Molecular and cellular biology 2003 (PubMed)
    Show all 2 references for ABIN2779719

More Antibodies against NPAS4 Interaction Partners

Human Neuronal PAS Domain Protein 4 (NPAS4) interaction partners

  1. This review summarizes the current knowledge of the roles that Npas4 may play in neuroinflammation and ischemia. [review]

  2. we provide the first evidence that Npas4 is expressed during embryonic development and that it may have a developmental role that is unrelated to its function in the adult brain

  3. These results provide insight into the mechanisms of NPAS4/ARNT (show ARNT Antibodies) dimerisation and transcriptional activation.

  4. a novel NXF signaling system on neural gene promoter may be a molecular target of the adverse effects of Sim2 (show SIM2 Antibodies) in the mental retardation of Down's syndrome

Mouse (Murine) Neuronal PAS Domain Protein 4 (NPAS4) interaction partners

  1. beta cell cytotoxicity of the calcineurin inhibitor (show RCAN1 Antibodies) and immunosuppressant tacrolimus (FK-506) was prevented by Npas4 overexpression.

  2. Results suggest that transcription of the Npas4 gene is downregulated by stress through DNA methylation (show HELLS Antibodies) of its promoter

  3. induction of Npas4 identifies the area influenced by cortical spreading depression propagation.

  4. Cortex activation by sensory conditioning was found to upregulate the expression of both Npas4 and c-Fos.

  5. Data showed that differential levels of Npas4 expression in the brain may regulate anxiety, depression and cognition related disorders.

  6. Npas4 regulates Mdm2 (show MDM2 Antibodies) expression during dendritic spine development in newborn olfactory bulb after sensory experience.

  7. we provide the first evidence that Npas4 is expressed during embryonic development and that it may have a developmental role that is unrelated to its function in the adult brain

  8. Study describes a transcriptional program that is induced by neuronal activity in inhibitory neurons; while neuronal activity induces expression of early-response transcription factors such as Npas4 in both excitatory and inhibitory neurons, Npas4 activates distinct programs of late-response genes in inhibitory and excitatory neurons.

  9. Our results reveal REST and microRNA dependent mechanisms that restrict NPAS4 expression to the brain

  10. sensory stimuli, by inducing NPAS4 and its target genes, differentially control spatial features of neuronal inhibition in a way that restricts the output of the neuron while creating a dendritic environment that is permissive for plasticity

NPAS4 Antigen Profile

Protein Summary

NXF is a member of the basic helix-loop-helix-PER (MIM 602260)-ARNT (MIM 126110)-SIM (see SIM2\; MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events (Ooe et al., 2004

Gene names and symbols associated with NPAS4

  • neuronal PAS domain protein 4 (NPAS4) antibody
  • neuronal PAS domain protein 4 (npas4) antibody
  • neuronal PAS domain-containing protein 4 (Tsp_02837) antibody
  • neuronal PAS domain protein 4 (Npas4) antibody
  • neuronal PAS domain protein 4a (npas4a) antibody
  • bHLHe79 antibody
  • LE-PAS antibody
  • MGC146621 antibody
  • npas4 antibody
  • Nxf antibody
  • PASD10 antibody
  • wu:fj52d04 antibody
  • zgc:136764 antibody

Protein level used designations for NPAS4

neuronal PAS domain protein 4 , HLH-PAS transcription factor NXF , neuronal PAS domain-containing protein 4 , neuronal PAS domain-containing protein 4-like , PAS domain-containing protein 10 , class E basic helix-loop-helix protein 79 , neuronal PAS4 , bHLH PAS type transcription factor NXF , bHLH-PAS type transcription factor NXF , limbic-enhanced PAS protein

GENE ID SPECIES
466676 Pan troglodytes
714161 Macaca mulatta
780368 Xenopus (Silurana) tropicalis
10899621 Trichinella spiralis
100029618 Monodelphis domestica
100052469 Equus caballus
100359105 Oryctolagus cuniculus
100397060 Callithrix jacchus
100442686 Pongo abelii
100481488 Ailuropoda melanoleuca
100505459 Ovis aries
100520174 Sus scrofa
100593820 Nomascus leucogenys
266743 Homo sapiens
266734 Rattus norvegicus
225872 Mus musculus
483711 Canis lupus familiaris
781497 Bos taurus
724016 Danio rerio
Selected quality suppliers for anti-NPAS4 (NPAS4) Antibodies
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