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Neuronal Pentraxin 1 Proteins (NPX1)

NPX1 encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Additionally we are shipping Neuronal Pentraxin 1 Antibodies (134) and Neuronal Pentraxin 1 Kits (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NPX1 18164 Q62443
NPX1 4884 Q15818
NPX1 266777 P47971
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Top Neuronal Pentraxin 1 Proteins at antibodies-online.com

Showing 9 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$827.20
Details
HOST_Escherichia coli (E. coli) Mouse His tag,GST tag 100 μg Log in to see 11 to 13 Days
$844.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 7 to 9 Days
$328.21
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,138.67
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$999.22
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

NPX1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)
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Human , ,
,
Rat (Rattus)

More Proteins for Neuronal Pentraxin 1 (NPX1) Interaction Partners

Mouse (Murine) Neuronal Pentraxin 1 (NPX1) interaction partners

  1. Results demonstrate a novel mechanism of neuronal death and predict that inhibition of NP1 expression is a promising strategy to prevent hypoxic-ischemic injury in immature brain

  2. results demonstrate that extracellular release of NP1 promote hypoxic-ischemic neuronal death possibly via surface clustering with GluR1 (show GRIA1 Proteins) at synaptic sites and that NP1, not its family member NP2 (show NRP2 Proteins), is involved in the neuronal death mechanisms

  3. Genetic deletion of NP1 prevents hypoxic-ischemic neuronal death by reducing synaptic clustering of GluR1 (show GRIA1 Proteins).

  4. These findings suggest that Narp (show NPTX2 Proteins) in the mPFC mediates the extinction of morphine conditioned place preference.

  5. our findings demonstrate a novel mechanism by which NP1 regulates mitochondria-driven hippocampal cell death

  6. NP1 facilitates the accumulation of BCL2-associated X protein (BAX (show BAX Proteins)) in mitochondria and regulates mitochondrial dynamics during apoptosis in mouse cerebellar granule neurons in culture.

  7. Neuronal pentraxin 1 induction in hypoxic-ischemic neuronal death is regulated via a glycogen synthase kinase-3alpha/beta dependent mechanism

  8. data indicate that the loss of NP1/2 disrupts several aspects of retinogeniculate development including the initial establishment of AMPAR transmission and the subsequent elimination of inappropriate circuit connections

  9. The Id3 (show ID3 Proteins) and NP1 genes become transcriptionally active after MyoD (show MYOD1 Proteins) induction in undifferentiated myoblasts. This is a stable, heritable event that does not need continued MyoD (show MYOD1 Proteins) activity & is not subject to negative regulation by activated H-Ras (show HRAS Proteins) G12V.

  10. Neuronal pentraxin 1 and 2 are necessary for early synaptic refinements in mammalian retina and dorsal lateral geniculate nucleus. May exert their effects through mechanisms paralleling known role of short pentraxins outside the CNS. (Pentraxin 1 (show CRP Proteins) and 2)

Human Neuronal Pentraxin 1 (NPX1) interaction partners

  1. NRP-1 (show NELL1 Proteins) was found to be overexpressed in gastric cancer (GC) tissues, and its expression correlates with the clinical staging, tumor differentiation and pathological types of gastric cancer.

  2. Both placental NRP1 and VEGF were expressed at lower levels in women with pre-eclampsia and homocysteine-treated mice, which may contribute to endothelial damage.

  3. NRP1 (show NELL1 Proteins) was targeted by miR130a and miR130b at the binding site of chromosome 10: 334668643466870, which was involved in the axon guidance signaling pathway.

  4. Semaphorin-3a (show SEMA3A Proteins), neuropilin-1 (show NRP1 Proteins) and plexin-A1 (show PLXNA1 Proteins) are axonal guidance molecules that have been recently implicated in regulating bone metabolism.

  5. neuropilin-1 (show NRP1 Proteins) is regulated in the oral epithelium and is selectively up-regulated during epithelial dysplasia

  6. NRP1 (show NELL1 Proteins) over-expression in miR (show MLXIP Proteins)-365 expressing cells could rescue invasion and growth defects of miR (show MLXIP Proteins)-365. In addition, miR (show MLXIP Proteins)-365 expression inversely correlated with NRP1 (show NELL1 Proteins) protein levels in malignant melanoma

  7. VEGF (show VEGFA Proteins)/NRP (show NAP1L1 Proteins)-1axis promotes progression of breast cancer via enhancement of epithelial-mesenchymal transition and activation of NF-kappaB (show NFKB1 Proteins) and beta-catenin (show CTNNB1 Proteins).

  8. Data show that binding of pleiotrophin (PTN (show PTN Proteins)) to neuropilin-1 (NRP-1 (show NRP1 Proteins)) stimulated the internalization and recycling of NRP-1 (show NELL1 Proteins) at the cell surface.

  9. Study found significant down-regulation of placental NRP-1 (show NELL1 Proteins) expression in fetal growth restriction pregnancies complicated with absent end-diastolic flow in the umbilical artery.

  10. PDE4D (show PDE4D Proteins) interacts directly with Neuropilins, positive regulators of Hedgehog (show SHH Proteins) signal transduction pathway.

Neuronal Pentraxin 1 (NPX1) Protein Profile

Protein Summary

This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors\; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

Gene names and symbols associated with Neuronal Pentraxin 1 Proteins (NPX1)

  • neuronal pentraxin 1 (nptx1)
  • neuronal pentraxin 1 (Nptx1)
  • neuronal pentraxin I (NPTX1)
  • neuronal pentraxin I (Nptx1)
  • neuropilin 1 (NRP1)
  • BDCA4 protein
  • CD304 protein
  • D11Bwg1004e protein
  • NP1 protein
  • NRP protein
  • VEGF165R protein

Protein level used designations for Neuronal Pentraxin 1 Proteins (NPX1)

neuronal pentraxin 1 , NP-I , neuronal pentraxin I , neuronal pentraxin-1 , 47 kDa taipoxin-binding protein , NP1 , neuropilin-1 , transmembrane receptor , vascular endothelial cell growth factor 165 receptor

GENE ID SPECIES
100158577 Xenopus (Silurana) tropicalis
18164 Mus musculus
4884 Homo sapiens
483356 Canis lupus familiaris
513538 Bos taurus
266777 Rattus norvegicus
422078 Gallus gallus
8829 Homo sapiens
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