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NPY encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. Additionally we are shipping NPY Antibodies (164) and NPY Proteins (13) and many more products for this protein.
Showing 10 out of 59 products:
Human NPY ELISA Kit for Competition ELISA - ABIN1979116
Allen, Adrian, Allen, Tatemoto, Crow, Bloom, Polak: Neuropeptide Y distribution in the rat brain. in Science (New York, N.Y.) 1983
Show all 9 references for ABIN1979116
Human NPY ELISA Kit for Competition ELISA - ABIN415029
Kaynar, Ozkorumak, Kural, Ulusoy, Cansiz, Akcan, M?s?r, Keles, Koc: The role of adipocytokines on depressive symptoms of patients with chronic kidney disease. in Renal failure 2013
Show all 5 references for ABIN415029
Rat (Rattus) NPY ELISA Kit for Competition ELISA - ABIN431547
López-Doval, Salgado, Fernández-Pérez, Lafuente: Possible role of serotonin and neuropeptide Y on the disruption of the reproductive axis activity by perfluorooctane sulfonate. in Toxicology letters 2015
Show all 2 references for ABIN431547
Neuropeptide Y mRNA content decreased 6 h after a meal, but increased to prefeeding levels by 24 h.
study implicates NPY as a potential target in antihypertensive therapies for preeclampsia patients
NPY is efficiently cleaved by FAP indicating a potential function for FAP in neuropeptide regulation within liver and cancer biology.
NPY plays important roles in the pathogenesis and pathophysiology of pituitary adenomas, as shown in this clinical study.
NPY levels were higher in both obese and non-obese PCOS patients compared to healthy controls.
Authors observed that NPY levels were decreased in two (show ATXN3 ELISA Kits)Machado-Joseph disease patients' cerebella.
Suggest IL-4 (show IL4 ELISA Kits) as marker of allergic airway inflammation in asthma, and roles for adiponectin (show ADIPOQ ELISA Kits) and neuropeptide Y in neurohormonal signaling.
This study suggests that NPY rs16147 T and rs16139 C minor alleles are associated with increased risk, whereas the minor allele T of the rs5574 is associated with a reduced risk of obesity.
NPY expression is increased during atherogenesis and in particular in unstable plaques
The C-terminal alpha-helix of Neuropeptide Y, which is formed in a membrane environment in the absence of the receptor, is unwound starting at T(32) to provide optimal contacts in a binding pocket within the transmembrane bundle of the NPY-Y2 receptor (show NPY2R ELISA Kits).
Data suggest that nutritional status and up-regulation of NPY in cerebrospinal fluid are related to disease progression in adults with chronic kidney disease (CKD); up-regulation of serum NPY levels may predict risk of cardiovascular events in CKD.
that preconditioning of mice with intermittent mild hypobaric hypoxia induces anxiolytic- and antidepressant-like effects which are accompanied by up-regulation of NPY which may suggest its mechanistic role
confirms the critical role of Y2 signalling to control neuropeptide Y and associated pro-opiomelanocortin (show POMC ELISA Kits) expression in the arcuate nuclei
Neuropeptide Y (NPY) has been shown to be important in the modulation of anxiety.
Diet composition, not calorie intake, rapidly alters intrinsic excitability of hypothalamic AgRP (show AGRP ELISA Kits)/NPY neurons in mice.
NPY might be involved in the pathogenesis of METH (show MTRR ELISA Kits)-induced atherogenic effects through NPY Y1 receptor pathway in ApoE (show APOE ELISA Kits) knockout mice
NPY deficiency leads to reduced orexigenic stimulation and water diffusion parameters
NPY suppresses cAMP activation of brown-like adipocytes via down-regulation o brown fat-relevant gene expression and mitochondrial function.
Data show that chronic caloric restriction (CR) alters hypothalamic agouti-related protein (Agrp (show AGRP ELISA Kits)) and neuropeptide Y (Npy) gene expression similarly in Ghrelin (show GHRL ELISA Kits)+/+, Ghrelin (show GHRL ELISA Kits)-/-, ghrelin receptor Ghsr (show GHSR ELISA Kits)+/+, and Ghsr (show GHSR ELISA Kits)-/- mice.
These data demonstrate a clear role for neuropeptide Y as a negative regulator of monocyte recruitment into the central nervous system and provide a new mechanism for suppression of retrovirus-induced neurological disease.
NPY levels are decreased in Machado-Joseph disease (MJD (show ATXN3 ELISA Kits)) and that NPY overexpression is able to alleviate neuropathology and motor deficits in different MJD (show ATXN3 ELISA Kits) mouse models.
Results show that the PP-fold is not important for recognition of peptide YY or neuropeptide Y at Y receptors.
NPY has a positive inotropic effect in isolated rat cardiac myocytes, which involves increase in Ca2 (show CA2 ELISA Kits)+ release after activation of Y1 NPY receptor
High dietary copper appears to increase feed intake and promote weight gain by enhancing NPY concentration and NPY mRNA expression level in the hypothalamus of pigs.
Neuropeptide Y was released from the lung tissue of brain-dead pigs, and its concentration was related to the extent of neurogenic pulmonary edema
Hormonal gene expression involved in residual feed intake in dairy cows may be related to the molecular regulation of the leptin (show LEP ELISA Kits)-NPY and insulin (show INS ELISA Kits) signaling pathways.
Data indicate that increased body weight gain during juvenile development accelerates sexual maturation in heifers, coincident with reciprocal changes in circulating concentrations of leptin (show LEP ELISA Kits) and hypothalamic neuropeptide Y (NPY) release.
There is a strong association between putative favorable allelic variants (SNP) of neuropeptide Y, leptin (show LEP ELISA Kits), and IGF-1 (show IGF1 ELISA Kits) genes, and residual feed intake, when animals were grazing on a high-quality, high-availability pasture.
The NPY SNP (NPY1) was associated with the prevalence of the animal being in calf 100 d after calving and 305-d milk yield in the first lactation.
NPY tended to increase serum growth hormone (show GH1 ELISA Kits), which appeared to be a consequence of increased pulse amplitude. Infusion of NPY also increased CSF (show CSF2 ELISA Kits) growth hormone-releasing hormone (show GHRH ELISA Kits).
Data show that PKA and PKC (show PKC ELISA Kits) pathways are involved in the differential regulation of production of the neuropeptides (Met)enkephalin, galanin (show GAL ELISA Kits), somatostatin (show SST ELISA Kits), NPY, and VIP (show Vip ELISA Kits).
The present investigation provides results of increased vasocontractile effect of NOR and decreased enhancing effect of NPY on NOR vasoconstriction in the rabbit facial artery after carotid occlusion that is related to altered endothelium function
NPY acts as an orexigenic factor in the zebrafish.
Neuropeptide Y/peptide YY receptor Y2 duplicate in zebrafish with unique introns displays distinct peptide binding properties.(
Developmental expression of zYb and zYc receptors suggests a role for neuropeptide Y (NPY) in organogenesis.
In this study described the the lateral line presence of NPY-like immunoreactivity (IR) in of the Antarctic nototheniod fish. Differences in size and cellular composition between the two neuromasts were presen NPY immunoreactivity.
A 2-day fast increased NPY gene expression in the supraoptic nucleus and paraventricular nucleus.
This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases.
, neuropeptide Ya
, prepro-neuropeptide Y
, pro-neuropeptide Y
, pro-neuropeptide Y preproprotein
, neuropeptide Yb
, pre-pro hormone
, preproneuropeptide Y, preproNPY