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Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. Additionally we are shipping NTSR1 Kits (7) and NTSR1 Proteins (3) and many more products for this protein.
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Human Polyclonal NTSR1 Primary Antibody for WB - ABIN2777123
Carraway, Hassan: Neurotensin receptor binding and neurotensin-induced growth signaling in prostate cancer PC3 cells are sensitive to metabolic stress. in Regulatory peptides 2007
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The roles of neurotensin and its receptor NTR-1 on sperm capacitation and acrosome reaction in mice are reported.
sleep traits and a relationship between Ntsr1 and anxiety and despair behaviors in knockout mice
Data show that NTS1 (show NTS Antibodies)(-/-) mouse is an animal model of schizophrenia, particularly for the dysfunction of the prefrontal cortex.
Ntsr1 knockout mice showed a higher freezing rate than wild type mice at both first and second exposures under the condition where a relatively weak unconditioned stimulus (footshock)
Ntsr1 receptor subtype is necessary for normal dopaminergic function.
These findings support the role for Ntsr1 in the mediation of the metabolic effect of xenin (show COPA Antibodies) as well as neurotensin (show NTS Antibodies).
Neurotensin (show NTS Antibodies) type 1 receptor does not play a role in NT-induced analgesia, but that it is clearly implicated in thermal and feeding regulation, weight control, and NT-induced hypolocomotion.
constant activation of NT1 receptor generates an oncogenic regulation
NT and NTR1 are part of network activated after mucosal injuries, and NT stimulates epithelial restitution, at least in part, through a COX-2 (show COX2 Antibodies) dependent pathway.
[(99m)Tc]Demotensin 6 shows a favourable preclinical profile and further testing in patients is warranted to monitor its eventual applicability as a radiotracer in the diagnostic imaging of NTS1 (show NTS Antibodies)-R-positive tumours.
Neurotensin (show NTS Antibodies) receptor-targeted oncolytic adenovirus co-expressing decorin (show DCN Antibodies) and Wnt (show WNT2 Antibodies) antagonist useful for systemic treatment of NTR-overexpressing pancreatic cancer.
high expression of NTSR1 is found in clinical NETs and promoter methylation is an important mechanism controlling the differential expression of NTSR1 and silencing of NTSR2 (show NTSR2 Antibodies) in NET cells
The presence of F358(7.42) causes the conserved W321(6.48) to adopt side chain orientation parallel to the lipid bilayer sealing the collapsed Na(+) ion pocket and linking the agonist with residues in the lower receptor part implicated in GPCR activation.
This study indicated that NTR1 may play an important role in tumor progression of gastric cancer
High expression levels of NTS (show NTS Antibodies) and NTSR1 predict a poor prognosis in glioma patients.
the NTR1 (show TFIP11 Antibodies)-HIF-1alpha (show HIF1A Antibodies)-VEGFalpha axis has a role in intestinal angiogenic responses and in the pathophysiology of colitis and inflammatory bowel disease
NTS (show NTS Antibodies)/NTSR1 complex enhances breast tumor aggressiveness via EGFR (show EGFR Antibodies)/HER2 (show ERBB2 Antibodies)/HER3 (show ERBB3 Antibodies) pathway.
Neurotensin (show NTS Antibodies) and its receptor NTSR1 causes EGFR (show EGFR Antibodies), HER2 (show ERBB2 Antibodies) and HER3 (show ERBB3 Antibodies) over-expression and their autocrine/paracrine activation in lung adenocarcinomas, confirming responsiveness to erlotinib.
This review provides a summary of current knowledge, mainly emerging from microdialysis studies, supporting the presence of a neurotensin receptor 1/D2 receptor (show DRD2 Antibodies) heteromer in the brain. [review]
Taken together, our results provided a novel regulatory mechanism for GPR39 (show GPR39 Antibodies)-1b in NTRS1 signaling.
Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion.
neurotensin receptor type 1
, neurotensin receptor 1 (high affinity)
, neurotensin receptor type 1-like
, high-affinity levocabastine-insensitive neurotensin receptor