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a single transmembrane protein highly expressed in embryonic tissues and involved in inducing apoptosis. Additionally we are shipping and many more products for this protein.
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The NRADD conditional and complete knockout mouse lines generated are new and useful tools to study the physiological roles of NRADD.
These results suggest a mechanism involving both the transmembrane domain and the death domain of p45 (show CASP1 Antibodies) to regulate p75 (show NGFR Antibodies)-mediated signaling.
p45 forms a complex with FADD and diminishes Fas-FADD mediated death signaling.
The authors show that the mammalian p75NTR (show NGFR Antibodies) homologue NRH2 critically regulates the expression of sortilin (show SORT1 Antibodies) on the neuronal cell surface and promotes p75NTR (show NGFR Antibodies) and sortilin (show SORT1 Antibodies) receptor complex formation, rendering cells responsive to proneurotrophins.
a single transmembrane protein highly expressed in embryonic tissues and involved in inducing apoptosis
death domain-containing membrane protein NRADD
, death domain containing membrane protein NRADD
, neurotrophin receptor homolog-2
, neurotrophin receptor-alike death domain protein
, neurotrophin receptor alike death domain protein
, p75-like apoptosis-inducing death domain protein PLAIDD