You are viewing an incomplete version of our website. Please click to reload the website as full version.

Neutral Sphingomyelinase (N-SMase) Activation Associated Factor Proteins (NSMAF)

NSMAF encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. Additionally we are shipping Neutral Sphingomyelinase (N-SMase) Activation Associated Factor Antibodies (46) and Neutral Sphingomyelinase (N-SMase) Activation Associated Factor Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NSMAF 8439 Q92636
NSMAF 18201 O35242
Rat NSMAF NSMAF 353233  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Neutral Sphingomyelinase (N-SMase) Activation Associated Factor Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

NSMAF Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF) Interaction Partners

Human Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF) interaction partners

  1. The interaction of FAN with receptor for activated C-kinase 1 (RACK1 (show GNB2L1 Proteins)) appears to be dependent on the folding of the WD repeats into a secondary structure, because no linear binding motifs are identified in the WD-repeat region of FAN.

  2. sphingolipid activator proteins like domain may stabilize the fold of acid sphingomyelinase (show SMPD1 Proteins)

  3. Regulation of NSMAF by TNF-alpha (show TNF Proteins) involves PRKCD (show PKCd Proteins) in lung epithelial cells.

Mouse (Murine) Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF) interaction partners

  1. FAN through promoting melanoma cellular motility and tumour invasiveness is critical for the tumour-promoting action of tumor necrosis factor (show TNF Proteins).

  2. FAN is not implicated in the development of methionine and choline deficient diet-induced non-alcoholic steatohepatitis.

  3. the role of FAN and IL-6 (show IL6 Proteins) in the inflammatory response initiated by endotoxin, implicating TNFalpha (show TNF Proteins)

  4. FAN mediates activation of N-SMase as well as regulation of lysosome size by signaling pathways that operate independent from activation/membrane recruitment of PKC.

  5. The results of this study suggest that PH-mediated plasma membrane targeting of FAN is critically involved in tumor necrosis factor (show TNF Proteins)-induced Cdc42 (show CDC42 Proteins) activation and cytoskeleton reorganization.

  6. This is the first report to demonstrate that TNFalpha (show TNF Proteins)-induced sickness behavior is fully mediated by TNF-R1 (show TNFRSF1A Proteins) and that the adaptor protein FAN is a necessary intracellular intermediate for sickness behavior

  7. these results indicate the involvement of FAN in TNF (show TNF Proteins)-induced gene expression and leukocyte recruitment, contributing to the establishment of the specific immune response.

Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF) Protein Profile

Protein Summary

This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with NSMAF

  • protein FAN (EDI_035100)
  • neutral sphingomyelinase (N-SMase) activation associated factor (NSMAF)
  • neutral sphingomyelinase (N-SMase) activation associated factor (Nsmaf)
  • AA959567 protein
  • C630007J05 protein
  • Fan protein

Protein level used designations for NSMAF

protein FAN , factor associated with N-SMase activation , factor associated with neutral sphingomyelinase activation

GENE ID SPECIES
5884688 Entamoeba dispar SAW760
8439 Homo sapiens
18201 Mus musculus
353233 Rattus norvegicus
Selected quality suppliers for Neutral Sphingomyelinase (N-SMase) Activation Associated Factor Proteins (NSMAF)
Did you look for something else?