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anti-Neutrophil Cytosolic Factor 1 (NCF1) Antibodies

The protein encoded by NCF1 is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase.

list all antibodies Gene Name GeneID UniProt
Anti-Mouse NCF1 NCF1 17969 Q09014
Anti-Human NCF1 NCF1 653361 P14598
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More Antibodies against Neutrophil Cytosolic Factor 1 Interaction Partners

Mouse (Murine) Neutrophil Cytosolic Factor 1 (NCF1) interaction partners

  1. data partly explains the discrepancy of the phenotypes reported earlier utilizing the Ncf1m1J mice or Ncf1 knockout mice.

  2. Data (including data from studies in transgenic mice) suggest that ability to generate Ncf1-derived superoxide, specifically in CD4 (show CD4 Antibodies)-positive T-lymphocytes, is key for development of autoimmune responses in type 1 diabetes.

  3. The Park7 (show PARK7 Antibodies) binds to p47(phox), a subunit of the NADPH oxidase (show NOX1 Antibodies), to promote NADPH oxidase (show NOX1 Antibodies)-dependent production of ROS (show ROS1 Antibodies).

  4. p47(phox)-dependent NADPH (show FDXR Antibodies) oxidases are a major glomerular source of reactive oxygen species, contributing to kidney injury

  5. p47phox mRNA expression was increased in diet-induced obese (DIO) mice. p47phox suppresses collateral vessel growth after femoral artery ligation in DIO mice.

  6. These findings suggest that a p47(phox)-dependent NAD(P)H (show NQO1 Antibodies) oxidase mediates the increase in diaphragm oxidants and contractile dysfunction in chronic heart failure.

  7. The present study provides evidence that augmented EGFRtk impairs vascular function by NADPH oxidase (show NOX1 Antibodies)-dependent mechanism. Therefore, EGFRtk and oxidative stress should be potential targets to treat vascular dysfunction in TD2.

  8. NOX2 (show CYBB Antibodies)/ROS (show ROS1 Antibodies) activity in macrophages signals the development of antigen-specific CD8 (show CD8A Antibodies)(+)T cell response.

  9. p47phox plays a critical role in the regulation of adventitial fibroblast proliferation and migration and may be a new therapeutic target for neointimal hyperplasia

  10. p47phox-Nox2 (show CYBB Antibodies)-dependent physiological reactive oxygen species signaling suppresses inflammation in aging.

Human Neutrophil Cytosolic Factor 1 (NCF1) interaction partners

  1. A rare mutation in NCF1 encoding p47phox of the leukocyte NADPH oxidase (show NOX1 Antibodies) causes lack of superoxide generation, leads to chronic granulomatous disease and was recently (1200-2300 years ago) introduced into the Kavkazi Jewish population

  2. Data show that diphenylene iodonium (DPI (show DSP Antibodies)) and apocynin can reduce hyperoxia-induced reactive oxygen species (ROS (show ROS1 Antibodies)) production by decreasing the translocation and level of NADPH Oxidase (show NOX1 Antibodies) p47phox.

  3. increased levels of gp91phox (show CYBB Antibodies), p47phox and p22phox (show CYBA Antibodies) likely account for the interferon-gamma (show IFNG Antibodies) mediated enhancement of dimethyl sulfoxide-induced Nox2 (show CYBB Antibodies) activity.

  4. Results identifies p47phox-dependent NADPH oxidase (show NOX1 Antibodies) activity as a critical component of Angpt-1 (show ANGPT1 Antibodies)-mediated endothelial barrier defense against classic inflammatory permeability factors.

  5. DCLRE1C (show DCLRE1C Antibodies) and NCF1 mutations have been found by whole-genome sequencing to cause primary immunodeficiency in unrelated patients.

  6. TLR8 (show TLR8 Antibodies), but not TLR7 (show TLR7 Antibodies), is involved in priming of human neutrophil reactive oxygen species production by inducing the phosphorylation of p47phox and p38 MAPK (show MAPK14 Antibodies).

  7. Reduced carotid but not coronary artery atherosclerosis in patients with chronic granulomatous disease despite the high prevalence of traditional risk factors raises questions about the role of NADPH oxidase (show NOX1 Antibodies) in the pathogenesis of atherosclerosis.

  8. Four novel mutations in the NCF1, NCF2 (show NCF2 Antibodies), and CYBB (show CYBB Antibodies) genees have been identified in chronic granulomatous disease patients in Morocco.

  9. Suggest eupafolin attenuated COX-2 (show COX2 Antibodies) expression leading to reduced production of prostaglandin E2 by blocking Nox2 (show CYBB Antibodies)/p47(phox) pathway.

  10. p47(phox) and Rac2 (show RAC2 Antibodies) accumulate only transiently at the phagosome at the onset of NADPH (show NQO1 Antibodies) activity and detach from the phagosome before the end of reactive oxygen species production.

Cow (Bovine) Neutrophil Cytosolic Factor 1 (NCF1) interaction partners

  1. Differential Roles of Protein Complexes NOX1 (show NOX1 Antibodies)-NOXO1 (show NOXO1 Antibodies) and NOX2 (show CYBB Antibodies)-p47phox in Mediating Endothelial Redox Responses to Oscillatory and Unidirectional Laminar Shear Stress.

  2. two novel splice variants designed as NCF1-TV1 (retained intron 6) and NCF1-TV2 (retained part of intron 8)encoding two putative truncated proteins (239AA and 283AA). Two splice variants were up-regulated in the mastitis-infected cows' mammary tissues, blood and neutrophils compared with these of healthy cows.

  3. A p47(phox) and Src kinase (show CSK Antibodies) activation of peroxide production by Nox2 (show CYBB Antibodies) appears to be an important contributor to vascular contractile mechanisms mediated through activation of protein kinase C (show PKC Antibodies).

Neutrophil Cytosolic Factor 1 (NCF1) Antigen Profile

Protein Summary

The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease.

Gene names and symbols associated with NCF1

  • neutrophil cytosolic factor 1 (p47phox) antibody
  • general transcription factor IIi (GTF2I) antibody
  • neutrophil cytosolic factor 1 (Ncf1) antibody
  • neutrophil cytosolic factor 1 (NCF1) antibody
  • neutrophil cytosolic factor 1 (ncf1) antibody
  • cb893 antibody
  • Ncf-1 antibody
  • NCF1A antibody
  • NOXO2 antibody
  • p47 antibody
  • p47phox antibody
  • SH3PXD1A antibody

Protein level used designations for NCF1

neutrophil cytosolic factor 1 , 47 kDa neutrophil oxidase factor , NADPH oxidase subunit (47 kD) , NADPH oxidase subunit (47kDa) , NCF-47K , neutrophil NADPH oxidase factor 1 , neutrophil cytosol factor 1 , p47-phox , 47 kDa autosomal chronic granulomatous disease protein , NADPH oxidase organizer 2 , NCF-1 , SH3 and PX domain-containing protein 1A , neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1) , nox organizer 2 , nox-organizing protein 2 , neutrophil cytosolic factor 1 (47kDa, chronic granulomatous disease, autosomal 1) , p47phox

GENE ID SPECIES
619225 Ciona intestinalis
100227162 Taeniopygia guttata
17969 Mus musculus
653361 Homo sapiens
281345 Bos taurus
378966 Danio rerio
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