Neutrophil Cytosolic Factor 1 (NCF1) ELISA Kits

The protein encoded by NCF1 is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse NCF1 NCF1 17969 Q09014
Anti-Human NCF1 NCF1 653361 P14598
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More ELISA Kits for Neutrophil Cytosolic Factor 1 Interaction Partners

Mouse (Murine) Neutrophil Cytosolic Factor 1 (NCF1) interaction partners

  1. The authors demonstrated a significant role of the host NADPH oxidase (show NOX1 ELISA Kits) in promoting chronic inflammatory pathology in the oviduct following chlamydial infection.

  2. data partly explains the discrepancy of the phenotypes reported earlier utilizing the Ncf1m1J mice or Ncf1 knockout mice.

  3. Data (including data from studies in transgenic mice) suggest that ability to generate Ncf1-derived superoxide, specifically in CD4 (show CD4 ELISA Kits)-positive T-lymphocytes, is key for development of autoimmune responses in type 1 diabetes.

  4. The Park7 (show PARK7 ELISA Kits) binds to p47(phox), a subunit of the NADPH oxidase (show NOX1 ELISA Kits), to promote NADPH oxidase (show NOX1 ELISA Kits)-dependent production of ROS (show ROS1 ELISA Kits).

  5. p47(phox)-dependent NADPH (show FDXR ELISA Kits) oxidases are a major glomerular source of reactive oxygen species, contributing to kidney injury

  6. p47phox mRNA expression was increased in diet-induced obese (DIO) mice. p47phox suppresses collateral vessel growth after femoral artery ligation in DIO mice.

  7. These findings suggest that a p47(phox)-dependent NAD(P)H (show NQO1 ELISA Kits) oxidase mediates the increase in diaphragm oxidants and contractile dysfunction in chronic heart failure.

  8. The present study provides evidence that augmented EGFRtk impairs vascular function by NADPH oxidase (show NOX1 ELISA Kits)-dependent mechanism. Therefore, EGFRtk and oxidative stress should be potential targets to treat vascular dysfunction in TD2.

  9. NOX2 (show CYBB ELISA Kits)/ROS (show ROS1 ELISA Kits) activity in macrophages signals the development of antigen-specific CD8 (show CD8A ELISA Kits)(+)T cell response.

  10. p47phox plays a critical role in the regulation of adventitial fibroblast proliferation and migration and may be a new therapeutic target for neointimal hyperplasia

Human Neutrophil Cytosolic Factor 1 (NCF1) interaction partners

  1. Decreased and increased copy numbers of NCF1 predispose to and protect against SLE.

  2. Lysophosphatidylcholines prime polymorphonuclear neutrophil through Hck (show HCK ELISA Kits)-dependent activation of PKCdelta (show PKCd ELISA Kits), which stimulates PKCgamma (show PRKCG ELISA Kits), resulting in translocation of phosphorylated p47(phox).

  3. There was an increased frequency of the NCF1-339 T allele in patients with systemic lupus erythematosus. The NCF1-339 T allele reduced extracellular ROS (show ROS1 ELISA Kits) production in neutrophils and led to an increase expression of type 1 interferon (show IFNA ELISA Kits)-regulated genes.

  4. Skeletal muscle protein expression of the NADPH oxidase (show NOX1 ELISA Kits) subunits p22(phox (show CYBA ELISA Kits)), p47(phox), and p67(phox (show NCF2 ELISA Kits)) was increased in obese relative to lean subjects, where p22(phox (show CYBA ELISA Kits)) and p67(phox (show NCF2 ELISA Kits)) expression was attenuated by exercise training in obese subjects.

  5. A novel role for Spns2 and S1P1 (show S1PR1 ELISA Kits)&2 in the activation of p47(phox) and production of reactive oxygen species involved in hyperoxia-mediated lung injury.

  6. Study provides evidence for a novel PKC-zeta (show PRKCZ ELISA Kits) to p47phox interaction that is required for cell transformation from blebbishields and ROS (show ROS1 ELISA Kits) production in cancer cells.

  7. Overexpression of p47phox is associated with increased migration/metastasis rate in melanoma.

  8. A rare mutation in NCF1 encoding p47phox of the leukocyte NADPH oxidase (show NOX1 ELISA Kits) causes lack of superoxide generation, leads to chronic granulomatous disease and was recently (1200-2300 years ago) introduced into the Kavkazi Jewish population

  9. Data show that diphenylene iodonium (DPI (show DSP ELISA Kits)) and apocynin can reduce hyperoxia-induced reactive oxygen species (ROS (show ROS1 ELISA Kits)) production by decreasing the translocation and level of NADPH Oxidase (show NOX1 ELISA Kits) p47phox.

  10. increased levels of gp91phox (show CYBB ELISA Kits), p47phox and p22phox (show CYBA ELISA Kits) likely account for the interferon-gamma (show IFNG ELISA Kits) mediated enhancement of dimethyl sulfoxide-induced Nox2 (show CYBB ELISA Kits) activity.

Cow (Bovine) Neutrophil Cytosolic Factor 1 (NCF1) interaction partners

  1. Differential Roles of Protein Complexes NOX1 (show NOX1 ELISA Kits)-NOXO1 (show NOXO1 ELISA Kits) and NOX2 (show CYBB ELISA Kits)-p47phox in Mediating Endothelial Redox Responses to Oscillatory and Unidirectional Laminar Shear Stress.

  2. two novel splice variants designed as NCF1-TV1 (retained intron 6) and NCF1-TV2 (retained part of intron 8)encoding two putative truncated proteins (239AA and 283AA). Two splice variants were up-regulated in the mastitis-infected cows' mammary tissues, blood and neutrophils compared with these of healthy cows.

  3. A p47(phox) and Src kinase (show CSK ELISA Kits) activation of peroxide production by Nox2 (show CYBB ELISA Kits) appears to be an important contributor to vascular contractile mechanisms mediated through activation of protein kinase C (show PKC ELISA Kits).

Neutrophil Cytosolic Factor 1 (NCF1) Antigen Profile

Antigen Summary

The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease.

Gene names and symbols associated with NCF1

  • neutrophil cytosolic factor 1 (p47phox) antibody
  • general transcription factor IIi (GTF2I) antibody
  • neutrophil cytosolic factor 1 (Ncf1) antibody
  • neutrophil cytosolic factor 1 (NCF1) antibody
  • neutrophil cytosolic factor 1 (ncf1) antibody
  • cb893 antibody
  • Ncf-1 antibody
  • NCF1A antibody
  • NOXO2 antibody
  • p47 antibody
  • p47phox antibody
  • SH3PXD1A antibody

Protein level used designations for NCF1

neutrophil cytosolic factor 1 , 47 kDa neutrophil oxidase factor , NADPH oxidase subunit (47 kD) , NADPH oxidase subunit (47kDa) , NCF-47K , neutrophil NADPH oxidase factor 1 , neutrophil cytosol factor 1 , p47-phox , 47 kDa autosomal chronic granulomatous disease protein , NADPH oxidase organizer 2 , NCF-1 , SH3 and PX domain-containing protein 1A , neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1) , nox organizer 2 , nox-organizing protein 2 , neutrophil cytosolic factor 1 (47kDa, chronic granulomatous disease, autosomal 1) , p47phox

GENE ID SPECIES
619225 Ciona intestinalis
100227162 Taeniopygia guttata
17969 Mus musculus
653361 Homo sapiens
281345 Bos taurus
378966 Danio rerio
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